Recent experimental and clinical research performed by outstanding
authorities has enabled us to characterize fundamental processes
that govern the regulation of salt and water content of the body.
Their results have provided not only an important gain of insight
into mechanisms at the cellular level but also the possibility to
integrate single cell activities into a complex organ function.
Moreover, this knowledge enables scientists to develop broader
concepts concerning the regulation of organ function and thus
contributes to a better understanding of the overall status in
health and disease. In the present volume some of these
physiologists and clinicians discuss principal questions of humoral
and non-humoral influences involved in the control of electro lyte
and fluid content of the organism. It contains three essential
topics: Data concerning basic principles of cell behaviour and
transport processes are followed by the description of natriuretic
substances and their influence on volume regulation. Finally,
attempts are undertaken to elucidate the meaning of these basic
principles for the explanation of the development of patholocigal
states. This symposion was held in honor to Professor H. P. Wolff,
one of the internatio nally wellknown pioneers in this field of
clinical research. The editors. wish to express their graditude to
the Melusin-Schwarz-Monheim GmbH for the generous support of the
symposion."
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