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Dynamic Brain Imaging - Multi-Modal Methods and In Vivo Applications (Hardcover, 2009 ed.)
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Dynamic Brain Imaging - Multi-Modal Methods and In Vivo Applications (Hardcover, 2009 ed.)
Series: Methods in Molecular Biology, 489
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The developing of in vivo neuroscience techniques is rapidly
improving the specificity and sensitivity of measurements of brain
function. However, despite improvements in individual methods, it
is becoming increasingly clear that the most effective research
approaches will be multi-modal. Thus, it is the researchers who are
familiar with many in vivo techniques who will be able to make the
most substantial contributions to our understanding of dynamic
brain function. In Dynamic Brain Imaging: Multi-Modal Methods and
In Vivo Applications, leading experts specializing in magnetic
resonance, electrophysiology, and optical imaging methods explain
basic principles of their respective techniques and demonstrate
their power in depicting functional activation patterns en route to
a basic understanding of the dynamic processes underlying various
neuroimaging signals. The novel results, from various species,
provide a new understanding of dynamics of neural activity that
span a wide spatiotemporal range. Numerous cutting-edge
applications are used as examples to illustrate enticing
possibilities of combining techniques toward studies of normal
function and disease. Exclusive examples of dynamic functional
imaging of the cerebral cortex, olfactory bulb, and retina are used
to demonstrate the effectiveness of each method for applications to
the neurosciences. State-of-the-art techniques described include
multi-photon optical imaging, multi-array electrical recordings,
heteronuclear magnetic resonance spectroscopy and functional
magnetic resonance imaging. Up-to-date and user-friendly, Dynamic
Brain Imaging: Multi-Modal Methods and In Vivo Applications is
designed to be accessible to both specialist neurophysiologists and
general neuroscientists. It reviews the fundamental, theoretical,
and practical principles of magnetic resonance, electrophysiology,
and optical methods as applied in the neurosciences and shows how
these tools can be used
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