Orthopedics and rheumatology, while separate specialties, have
become close conceptually because advances in bone and joint
biology enable practitioners to approach clinical problems
comprehensively. This is especially true for the bench and
translational scientists. Recently, there has been renewed interest
in the role played by bone in the development of osteoarthritis,
including targeting bone as a potential therapeutic approach.
The molecular and cellular approaches toward the relationship of
joint and bone problems distinguish this from other books on
osteoarthritis or skeletal medicine. Emphasis on genetics and on
newer viewpoints and approaches, exemplified by the possible effect
of subchondral bone on osteoarthritis, gives a wider viewpoint to
the reader and may make possible novel approaches to solving a
clinical problem. The book will therefore also interest experienced
specialists, thereby broadening readership. Authors are
internationally recognized experts in their field.
Topics discussed include the role of bone in osteoarthritis,
ranging from basic cell and molecular biology to genetics and
biomechanics. How this information may be used for new treatment
approaches will also be covered.
This book, intended for students, researchers and clinicians,
provides information that enables the novice to become oriented and
the practitioner to update knowledge. No other book combines
information on the relationship of bone to the development of
osteoarthritis, or treats the pathophysiology of joints in the same
way. This volume, like the others in Topics in Bone Biology series,
encompasses aspects of many specialties, including rheumatology,
orthopedics, endocrinology, oncology, dentistry, geriatrics,
nursing and chiropractic medicine.
General
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