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High Performance Liquid Chromatography (Paperback, Softcover reprint of the original 1st ed. 1979)
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High Performance Liquid Chromatography (Paperback, Softcover reprint of the original 1st ed. 1979)
Series: Chemical Laboratory Practice
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Modern liquid column chromatography (LC) has developed rapidly
since 1969 to become a standard method of separation. If the
statisticians are to be believed, the recent growth of LC has been
the most specta cular development in analytical chemistry and has
not yet abated be cause its vast potential for application remains
to be fully exploit ed. Significant factors contributing to this
continued rise are the simplicity and low cost of the required
basic equipment and the rela tive ease of acquiring and
interpreting the data. Unfortunately, in LC, as so often in the
field of analytical chemistry, the available commercial instruments
are frequently far more complicated - and consequently far more
expensive - than is nec essary for routine application. Therein
also lies the risk of propa gating a "black box" philosophy that
would be particularly detrimen tal to chromatography. Moreover, it
appears to have been forgotten, as was done previously with gas
chromatography, that inadequate sep aration by a column can be
remedied only with great difficulty, if at all, by electronic
means. Also, whether the capillary columns recent ly advocated with
great enthusiasm for LC will fulfill the expecta tions of their
proponents is highly questionable unless someone comes up with some
new and revolutionary ideas."
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