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Cell Culture Methods for In Vitro Toxicology (Paperback, Softcover reprint of the original 1st ed. 2001)
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Cell Culture Methods for In Vitro Toxicology (Paperback, Softcover reprint of the original 1st ed. 2001)
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Cell Culture Methods for in vitro Toxicology introduces the reader
to a range of techniques involved in the use of in vitro cell
culture in toxicological studies. It deals with major cell types
studied in the field of toxicology and will be useful for anyone
wishing to start work with animal cell cultures or to refresh their
knowledge relating to in vitro cell models. Fundamental chapters
deal with the general biology of cytotoxicity and cell
immortalisation these are key issues for in vitro systems
addressing the 3Rs' principle. Up-to-date overviews deal with the
use of cells from liver, brain and intestine. In addition,
biochemical analysis of cell responses, biotransformation pathways
in cells and recombinant approaches to the early detection of cell
stress are also covered in detail. Prominent features of in vitro
technologies also include regulation, biosafety and
standardisation. Dedicated chapters deal with these issues in a
practical way in order to lead the reader to the right source of
information. This book provides an up-to-date, informative and
practical review of cell culture methods for in vitro toxicology.
It will be of equal benefit to students and experienced
toxicologists with little experience of in vitro cell culture.
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