This volume provides a timely and thorough review of the current
state of understanding of a fascinating type of cell that is
capable of forming many or all cells in the body. In humans and
other mammals embryonic stem cells, the immediate offspring of the
fertilized egg, are capable of forming any type of cell in the
body. Moreover stem cells are present in many different tissues in
adults that are capable of dividing and differentiating into the
specific cell types that comprise the organ in which they reside.
A major focus of the book is to provide the reader with up-to-date
information on the molecular mechanisms that regulate the
proliferation, differentiation and survival of stem cells, and how
aging and age-related disease impacts on stem cells. Leading
authorities detail the properties and therapeutic potential of
embryonic stem cells and stem cells of the nervous and immune
systems, muscle and bone. Particularly exciting are emerging
technologies for using stem cells to treat human age-related
diseases including cardiovascular disease, diabetes,
neurodegenerative disorders such as Parkinson's and Alzheimer's
diseases.
This book will be a valuable reference for developmental
biologists and for scientists and clinicians who study and treat a
variety of diseases.
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