Award-winning journalist Charlotte Bauer's warm, witty and wise quest for the meaning of life after youth and how to navigate the menopausal years.

A deliciously funny and sage guide to midlife - an unscientific, flaws-and-all account of one woman's adventures and misadventures through the dark comedy of the wilderness years.

Through her own experiences as a fifty-something woman, and those of her three sisters, her indomitable mum and rebellious auntie, Charlotte tackles the big questions every woman seeks answers to at this time of our lives - chiefly: How the hell am I going to get over being young in a world obsessed with youth?

Written with warmth, wisdom and irreverence this guide to midlife is perfect for readers of Nora Ephron, Caitlin Moran and India Knight.

John Rebus stands accused: on trial for a crime that could put him behind bars for the rest of his life. Although it's not the first time the legendary detective has taken the law into his own hands, it might be the last. What drove a good man to cross the line? Or have times changed, and the rules with them? Detective Inspector Siobhan Clarke faces Edinburgh's most explosive case in years, as a corrupt cop goes missing after claiming to harbour secrets that could sink the city's police force. But in this investigation, it seems all roads lead to Rebus - and Clarke's twin loyalties to the public and the police will be tested to their limit. A reckoning is coming - and John Rebus may be hearing the call for last orders...

Maintaining physical and mental performance with a revolutionary diet that helps prevent age-related diseases. Sears explains that it is possible to reverse our 'biological' age (which is different to our 'chronological' age) if we look at our hormones and our diet. It is crucial to maintain the right balance of hormones in our bodies - ageing is not necessarily about the decreasing of certain hormones but rather how they effectively communicate with each other to maintain equilibrium. The Zone is a revolutionary diet plan which advocates a lower intake of carbohydrates which convert to sugar creating a diabetic-like condition. If we eat more protein and monosaturate fats we enter the Zone of optimum metabolic function. This diet has been proven in preventing age-related diseases: heart disease and diabetes (non-insulin dependent diabetes largely occurs in older age). Sears explores the activity of hormones as we age and gives a dietary plan (and supplement advice) to maintain peak performance: * calorie restriction without hunger or deprivation * insulin, cortisol, seratonin and eicosanoids * oestrogen and the menopause * testosterone as men and women age * DHEA, melatonin - are these hormonal supplements merely hype? * your thyroid gland and how it affects metabolism * exercise and the anti-ageing Zone lifestyle 'pyramid'

In this paradigm-shifting book from acclaimed Harvard Medical School doctor and one of TIME magazine's 100 most influential people on earth, Dr. David Sinclair reveals that everything we think we know about ageing is wrong, and shares the surprising, scientifically-proven methods that can help readers live younger, longer. For decades, the medical community has looked to a variety of reasons for why we age, and the consensus is that no one dies of old age; they die of age-related diseases. That's because ageing is not a disease - it is inevitable. But what if everything you think you know about ageing is wrong? What if ageing is a disease? And that disease is curable. In LIFESPAN, Dr. David Sinclair, one of the world's foremost authorities on genetics and ageing, argues just that. He has dedicated his life's work to chasing more than a longer lifespan - he wants to enable people to live longer, healthier, and disease-free well into our hundreds. In this book, he reveals a bold new theory of ageing, one that pinpoints a root cause of ageing that lies in an ancient genetic survival circuit. This genetic trick - a circuit designed to halt reproduction in order to repair damage to the genome -has enabled earth's early microcosms to survive and evolve into more advanced organisms. But this same survival circuit is the reason we age: as genetic damage accumulates over our lifespans from UV rays, environmental toxins, and unhealthy diets, our genome is overwhelmed, causing gray hair, wrinkles, achy joints, heart issues, dementia, and, ultimately, death. But genes aren't our destiny; we have more control over them than we've been taught to believe. We can't change our DNA, but we can harness the power of the epigenome to realise the true potential of our genes. Drawing on his cutting-edge findings at the forefront of medical research, Dr. Sinclair will provide a scientifically-proven roadmap to reverse the genetic clock by activating our vitality genes, so we can live younger longer. Readers will discover how a few simple lifestyle changes - like intermittent fasting, avoiding too much animal protein, limiting sugar, avoiding x-rays, exercising with the right intensity, and even trying cold therapy - can activate our vitality genes. Dr. Sinclair ends the book with a look to the near future, exploring what the world might look like - and what will need to change - when we are all living well to 120 or more. Dr. Sinclair takes what we have long accepted as the limits of human potential and mortality and turns them into choices. THE EVOLUTION OF AGEING is destined to be the biggest book on genes, biology, and longevity of this decade.

A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people.

It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan?

In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.”

This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger.

Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.

'I am blown away by the level of detail Phil Cavell brings to his work.' - Elinor Barker MBE, multiple world champion and Olympic gold medallist 'The Midlife Cyclist is a triumph' - Cycling Plus 'An amazing accomplishment... a simple-to-understand precis of your midlife as a cyclist - you won't want to put it down.' - Phil Liggett, TV cycling commentator 'Phil is eminently qualified to write The Midlife Cyclist. Well, he is certainly old enough.' - Fabian Cancellara, Tour de France rider and two-time Olympic champion Renowned cycling biomechanics pioneer, Phil Cavell, explores the growing trend of middle-aged and older cyclists seeking to achieve high-level performance. Using contributions from leading coaches, ex-professionals and pro-team doctors, he produces the ultimate manifesto for mature riders who want to stay healthy, avoid injury - and maximise their achievement levels. Time's arrow traditionally plots an incremental path into declining strength and speed for all of us. But we are different to every other generation of cyclists in human history. An ever-growing number of us are determined to scale the highest peaks of elite physical fitness into middle-age and beyond. Can the emerging medical and scientific research help us achieve the holy triumvirate of speed and health with age? The Midlife Cyclist offers a gold standard road-map for the mature cyclist who aims to train, perform and even race at the highest possible level.

'Maisie's knowledge of hormones changed my life... you need this book' Anna Jones 'Hill's advice is straightforward and no-nonsense' The Guardian 'An informative must-read for any woman - whatever their age' Vogue online During perimenopause three quarters of women will experience symptoms such as mood changes, insomnia, hot flushes, and night sweats, but there is little in the way of evidence-based information out there to help and guide us. Perimenopause Power is the essential handbook to understanding what the hell's going on and to empower us to improve our experience of the dreaded 'change'. Maisie Hill, the highly qualified women's health expert, best-selling author of Period Power and founder of The Flow Collective, takes us through the physiological changes of perimenopause and menopause, step by step, with calm positivity. In this invaluable guide she shares tips and advice to support women through the challenge of wildly fluctuating hormones. A must-read for anyone looking for a well-researched, evidenced-based book on perimenopause and menopause that gives women the information they need to address their hormonal needs. Perimenopause Power will help women to understand what's going on with their bodies and how to deal with troublesome symptoms, and share valuable insights into making it a positive and powerful experience. 'Maisie Hill helps you understand the changes in your body and psyche during the lead-up to menopause and how to handle symptoms.' Top Sante 'Maisie Hill gets rid of myths, sheds light and allows for an open, honest and much-needed conversation' Mind

'A stunner ... If you haven't got this book in your house, I don't know why' Chris Evans 'A startling wake-up call . . . Writing with the vim of a Bill Bryson and the technical knowledge of a scientist, Steele gives us a chance to grasp what's at stake' Independent 'An exhilarating journey . . . Steele is a superb guide' Telegraph 'A fascinating read with almost every page bursting with extraordinary facts . . . Read it now' Mail on Sunday Ageless is a guide to the biggest issue we all face. Ageing - not cancer, not heart disease - is the world's leading cause of death and suffering. What would the world be like if we could cure it? Living disease-free until the age of 100 is achievable within our lifetimes. In prose that is lucid and full of fascinating facts, Ageless introduces us to the cutting-edge research that is paving the way for this revolution. Computational biologist Andrew Steele explains what occurs biologically as we age, as well as practical ways we can slow down the process. He reveals how understanding the scientific implications of ageing could lead to the greatest discovery in the history of civilisation - one that has the potential to improve billions of lives, save trillions of dollars, and transform the human condition.

The United Nations Madrid International Plan of Action on Ageing (MIPAA) offers a bold new agenda for handling the issue of ageing in the 21st-century. It focuses on three priority areas: older persons and development; advancing health and well-being into old age; and ensuring enabling and supportive environments. This book brings together global perspectives on the MIPAA and focusses on and assesses the success and failures of governments to implement its recommendations. Despite its pivotal importance in international ageing policy, the MIPAA has been relatively neglected by academics in their writings and studies. This book mitigates this analytical and empirical cavity. Each chapter focuses on one specific geographical region and addresses five key themes: National ageing situation; Twenty years of MIPAA; Ensuring ageing with dignity; Healthy and active ageing in a sustainable world; and Priorities for the future. It presents an overall summary of the findings, future challenges and opportunities related to ageing, recommendations for future actions to be taken, and policy adjustments needed. The authors also present lessons that were learnt from managing the impact of COVID-19 on older people, together with an outlook on the most immediate priorities for the future so that the recommendations in the MIPAA are achieved in post-COVID-19 and sustainable ethical scenarios. An important contribution towards the advancement of ageing policy, the book will be indispensable to students and researchers of gerontology, ageing, and health. It will also be of interest to policy makers, geriatricians, dementia care specialists, social policy makers responsible for ensuring active and healthy ageing, and all public sector departments which have specific responsibilities towards improving the quality of life of older adults.

According to the United Nations, the number of people aged 60 years or over in the world is projected to be 1.4 billion in 2030 and 2.1 billion in 2050. Endocrinologists and other clinicians face the challenge of caring for the elderly. To do so, they need to incorporate geriatric principles into their clinical practice. Endocrinology of Aging: Clinical Aspects in Diagrams and Images presents chapters in a way that allows the reader to incorporate concepts and main facts of complex subjects in a visual way. As the global population becomes older, the need for a deeper understanding of geriatric pathology increases, and with it, the access to educational resources for the endocrinology and metabolism of aging.

Understanding phytochemical-gene interactions provides the basis for individualized therapies to promote health as well as prevent and treat disease. The authors of Phytochemicals: Nutrient-Gene Interactions examine the interactions between phytochemicals and the human genome and discuss the impact these interactions have on health, aging, and chronic conditions such as inflammation, heart disease, obesity, type II diabetes mellitus, and cancer.

Keeping pace with the most important trends in phytochemical research, the authors accentuate the latest understanding on the use of controlled clinical trials, new screening technologies, and the completed human genome project for researching the pharmacokinetics, safety, and efficacy of phytochemicals. The book covers a balanced range of topics beginning with experimental strategies and methodologies for identifying significant interactions between diet, genetic variants, and different markers of cardiovascular disease, inflammation, and obesity. Different authors explain the mechanisms of protective action that link diets rich in omega-3 fatty acids, unsaturated fats, fruits, vegetables, and whole grains with a decreased risk of chronic and degenerative diseases. They also review and summarize epidemiological research on plant-based foods and dietary patterns supporting the beneficial role of phytochemicals in health promotion and disease prevention.

Phytochemicals: Nutrient-Gene Interactions illustrates the growing role of nutrigenomics and nutrigenetics in disease prevention and in the responsible development of safe and effective phytochemical products within the food, pharmaceutical, and supplement industries.

The Last Years of Long Lives is a unique account of that period of old age which precedes death. Based on 400 complete individual histories and covering a twenty-year period, it looks at the experiences of people over eighty years old in three important areas: disability, family life and health care. Using the life-course approach to research, it reveals rich data about the contributions of formal and informal care and how life expectancy and experiences of disability interact with experiences of care.

The reader is invited to conceptualise these phenomena as processes in continuous time - processes that are sometimes long and complex, sometimes short and simple - and learns about the four types of disability career before death. At the same time, the author presents a three-stage model of informal care and examines the main patterns of formal service use.

The Last Years of Long Lives presents a new way of looking at old age for students, researchers, practitioners and policy makers and gives a comprehensive picture of what has been called 'the fourth age'.

The world's foremost expert shares advice on later-in-life ADHD, tackling everything from finances, parenting, planning for retirement, social life and work, in this practical and helpful guide for those with and without a diagnosis. Do you... · Forget to pay bills? · Live in a disorganised environment? · Struggle with mental health? · Procrastinate on projects, even ones that initially excite you? · Have high levels of conflict with those close to you? · Have a child diagnosed with ADHD and/or a family history of learning disorders? If some of these patterns sound familiar, you might understandably fear the onset of dementia, but you may have undiagnosed attention deficit hyperactivity disorder (ADHD). ADHD in adults is one of the most common disorders. Living with ADHD in our later years is hugely influenced by co-occurring issues, such as anxiety, depression or low self-esteem. In addition, the presence of learning disorders, heightened levels of stress, the presence or lack of support from others, and the number of people we are responsible for, can all complicate and intensify the effects of ADHD. The good news is that you've come to the right place to learn more about how to lead a calmer, happier, more productive life. Dedicated to the health and wellbeing of today's older adults with ADHD, Still Distracted After All These Years offers strategies to build a support system, gain better control over your daily life and create a more ADHD-friendly retirement.

Wisdom Mind is a scientifically tested mindfulness program for older adults - those who are cognitively healthy, as well as those who may be experiencing what is referred to as subjective cognitive decline. While mindfulness is already known to benefit a wide variety of individuals, the unique strengths of this program are the ways in which it is tailored specifically to older adults. Session content is keyed to common concerns of older adults (such as cognitive slip-ups, loss, and grief), and incorporates strategies for building upon mindfulness practices in a sequence of increasing difficulty as well as strategies to promote learning and integration. Designed to be used alongside the companion Facilitator Guide, this session-by-session Participant Workbook provides detailed information on how to take part in the program, as well as the reasoning behind why certain practices and strategies are provided at different times and in different ways. As such, it will be of interest to those familiar with mindfulness as well as those new to the practice. A companion website provides downloadable meditation audio recordings that participants can access throughout the program.

A practical guide to how we can positively adapt to a changing world, from the internationally bestselling authors of The 100-Year Life 'The London Business School professors Andrew J. Scott and Lynda Gratton have been predicting how society must adapt for years. Now they have a post-pandemic road map for us all' Sunday Times Smart new technologies. Longer, healthier lives. Human progress has risen to great heights, but at the same time it has prompted anxiety about where we're heading. Are our jobs under threat? If we live to 100, will we ever really stop working? And how will this change the way we love, manage and learn from others? One thing is clear: advances in technology have not been matched by the necessary innovation to our social structures. In our era of unprecedented change, we haven't yet discovered new ways of living. Drawing from the fields of economics and psychology, Andrew J. Scott and Lynda Gratton offer a simple framework based on three fundamental principles (Narrate, Explore and Relate) to give you the tools to navigate the challenges ahead. The New Long Life is the essential guide to a longer, smarter, happier life.

About preventing, preparing, coping How do I know if I have dementia, and how will I live with it if I do? Can people with dementia consent to sex? Can they choose euthanasia for their future selves? And can we prevent or push back its onset? Chances are you know someone with dementia, but how well do you really understand the condition? Dementia is a complex interplay of biological, social and psychological factors, and understanding it means understanding more about society and ourselves. Approaching the topic through 20 insightful questions, Dr Kate Gregorevic explains the physical state of dementia, how to relate the diagnosis to real life, what questions to ask your doctor, what might be done to prevent the condition, and how we can make our homes and society better for people with dementia. While this book tackles some uncomfortable questions, its purpose is to help - to prevent, to prepare, to cope and to understand - and provide you with strategies for moving forward.

The honest, compassionate and vital guide to getting older, from dementia to finances, medication to care homes 'The most important book about the second half of your life you'll ever read. I wish everyone in the UK could be under Dr Lucy's care' SANDI TOKSVIG 'This warm and compassionate book gets to the heart of older age' THE BRITISH GERIATRICS SOCIETY ________ Now more than ever, we need to talk about getting older. Many of us are living to a very great age. But how do we give those we love, and eventually ourselves, long lives that are as happy and healthy as possible? Dr Lucy's book gives us answers to the questions we can voice - and those that we can't. This essential guide will guide you through those important conversations around growing older, answering every question you might have, including: * How do we start the conversation? * How do we ask whether it's worth taking seven different medicines? * Is it normal to find you're falling out of love with someone, as they disappear into dementia? * Should Dad be driving, and if not, who can stop him? * What are the secrets of the best care homes? * When does fierce independence become bad behaviour? * How do you navigate near-impossible discussions around resuscitation and intensity of treatments? * And who decides what happens when we become ill? Serious, funny, kind and knowledgeable, this readable book helps guide us through essential conversations about getting older that go straight to the heart of what matters most.

Just what is the andropause? Although acceptance of the andropause concept by the medical community is growing, it is still a hotly debated issue. But as a busy clinician you have patients to treat and you need information. So where can you find the information you need to understand, diagnose, and treat this condition? Androgen Deficiency in the Adult Male: Causes, Diagnosis and Treatment distills the knowledge acquired by author Dr. Malcolm Carruthers in his 25 years of research and clinical experience in diagnosing and treating the andropause into a comprehensive, detailed clinical resource. Dr. Carruthers documents the history of the search for testosterone treatment from antiquity to the awarding of the Nobel Prize to Adolf Butenandt and Leopold Ruzicka for synthesizing testosterone and patenting its production some 4,000 years later. He discusses the causes of androgen deficiency, the male menopause or andropause, and recent advances in its diagnosis. The text includes reviews of the literature in each section and a fund of bibliographic references gleaned from the author's years of research in this field. This combination of features makes Androgen Deficiency in the Adult Male: Causes, Diagnosis and Treatment an invaluable and practical clinical guide, a complete and detailed reference volume, and a cohesive and readable textbook.

A deliciously funny and sage guide to midlife - an unscientific, flaws-and-all account of one woman's adventures and misadventures through the dark comedy of the wilderness years. Through her own experiences as a fifty-something woman, and those of her three sisters, her indomitable mum and rebellious auntie, Charlotte tackles the big questions every woman seeks answers to at this time of our lives - chiefly: How the hell am I going to get over being young in a world obsessed with youth? Written with warmth, wisdom and irreverence this guide to midlife is perfect for readers of Nora Ephron, Caitlin Moran and India Knight.

Sleeping patterns change with age, whether we are growing up, or growing old. While most people are prepared for the rapidly altering sleep patterns of growing children, the evidence suggests that many are unprepared for additional sleep changes in later life, either in themselves or in others. In this book, originally published in 1987, two research disciplines - social gerontology and sleep research - are brought together with the aim of providing a straightforward account of how sleep is changed and disrupted by the biological and social impact of ageing. Attention then focuses on the personal and clinical response to these changes. The use of sleeping drugs among elderly people is critically examined, and effective alternatives, including self-help practices and psychological therapies, are described. The influence of ageing on the recall and content of dreams is also considered. In the final chapter, the author comments on current styles of responding to sleep problems in old age and discusses the need and the scope for change. This book deals with topics of universal interest and provides valuable information for those professionally as well as personally concerned with sleep quality in later life, including health professionals (nurses, doctors, psychologists etc.) working with elderly people, gerontologists, and sleep researchers.

This title includes a number of Open Access chapters. Sarcopenia-the loss of muscle mass and strength that occurs with advancing age-is a major health challenge, particularly in North America, Europe, and Japan, which have large aging populations. This compendium volume is a valuable addition to the existing literature, providing state-of-the-art information on the most effective prevention and treatment options. Included are research articles on nutrition management and the prevention of sarcopenia; protein therapy for sarcopenia; effect of exercise on sarcopenia; and other therapeutic strategies, including antioxidants and steroids.

The Last Years of Long Lives is a unique account of that period of old age which precedes death. Based on 400 complete individual histories and covering a twenty-year period, it looks at the experiences of people over eighty years old in three important areas: disability, family life and health care. Using the life-course approach to research, it reveals rich data about the contributions of formal and informal care and how life expectancy and experiences of disability interact with experiences of care. The reader is invited to conceptualise these phenomena as processes in continuous time - processes that are sometimes long and complex, sometimes short and simple - and learns about the four types of disability career before death. At the same time, the author presents a three-stage model of informal care and examines the main patterns of formal service use. The Last Years of Long Lives presents a new way of looking at old age for students, researchers, practitioners and policy makers and gives a comprehensive picture of what has been called 'the fourth age'.

Look 15 years younger in 2020 with Eva Fraser's easy facial workout ___________ Facial Yoga is THE non-surgical way to achieve a facelift - and help you look 15 years younger! 'Facial exercises may significantly reduce signs of ageing' New York Times In the ORIGINAL facial fitness classic, Eva Fraser shows you how straightforward exercises can help eliminate dark circles, firm your jaw line, tone your neck, plump cheeks and so much more . . . leaving your skin with a natural, youthful glow. For nearly 40 years, Eva Fraser has been practicing her facial workout techniques - and the results are remarkable. The premise is simple: the muscles in your face, if left inactive, will become as saggy as those in any other part of your body. In order to tone them up, they need to be exercised. This book includes information on why the face ages, how skin works and what can be done about it, as well as the easy exercise plan that Eva swears by. ___________ What do readers think? 'They really do work!' 5* Reader Review 'I have only been doing them for 4 weeks and they have made a difference' 5* Reader Review 'Eva Fraser gives a fool proof method to a younger face' 5* Reader Review 'A chemical free way to firm up those looks!' 5* Reader Review