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Books > Medicine > Pre-clinical medicine: basic sciences > Human reproduction, growth & development > Human growth & development > Maturation & ageing
In Slavic studies, aging and old age have thus far been only marginal concerns. This volume brings together the scattered research that has been done up to now on aging as represented and narrated in Slavic literatures. The essays investigate Bosnian/Croatian/Serbian, Polish, Russian, Slovak, Slovene and Ukrainian representations of age/aging in various literary genres and epochs and analyze age as a powerful marker of difference and as constitutive of social relations and personal identity.
The U.S. population is getting older, and Americans are living longer, on average, than they ever have before. As they age, people are healthier and more active than the generations before them and have fewer functional limitations such as difficulty walking or blindness. Studies show that people are happier on average as they advance into their later decades and enjoy high levels of accumulated knowledge and experience. Getting older is a time of social, emotional, mental, and physical change. Retirement might change how a person interacts socially every day, affecting a persons mood and well-being. Cognitive aging--the normal process of cognitive change as a person gets older--can begin, or a permanent change in physical function may arise. Technology offers a path for people who are navigating these changes potentially to prevent or minimise the risks associated with them and to enhance peoples ability to live their lives fully. The Presidents Council of Advisors on Science and Technology (PCAST), seeks to identify technologies and policies that will maximise the independence, productivity, and engagement of Americans in their later years. This book focuses on four key changes older Americans often experience: hearing loss; loss of social engagement and connectivity; cognitive change; and physical change.
This book reviews research on presently known theories and mechanisms responsible for the rate of ageing and maximum longevity of different animals including birds, mammals and humans (to explain how" do we age and the velocity of the ageing process). In addition, this book deals with the historical evolutionary explanations of ageing and longevity ("why" do we age). The mechanisms discussed include mitochondria and oxygen free radicals, the presence of macromolecules constitutively highly resistant to deleterious modification in the tissues of long-lived animals, insulin/IGF-1 like signalling, telomere shortening, dietary restrictions, and other proposed molecular mechanisms.
Ageing is an inevitable biological process that affects most living organisms. The link between metabolic rate and reactive oxygen species production is an important and long-standing question, and a source of much controversy. A by-product of cell respiration in mitochondria is the formation of reactive oxygen species due to electron leakage from the electron transport chain during oxidative phosphorylation. In simple terms, humans are ageing due to oxygen consumption. Damage induced by oxygen appears to be the major contributor to ageing and the degenerative diseases of ageing such as cancer, cardiovascular disease, immune system decline, and brain dysfunction. This book presents the reasons for oxidative stress formation and the answer to why during the course of evolution the process of free radical damage and defense did not become more perfect so as to produce less free radicals.
Hypertension and osteoporosis are two major age-related diseases. They are clinically silent disorders with high morbidity and mortality and the link between them has been reported recently with inconclusive evidence. This book presents and discusses research in this field which will improve our understanding of the relationship between high blood pressure and bone loss. It will begin by examining the clinical and experimental evidence of the involvement of the Renin-Angiotensin System (RAS), playing a central role in blood pressure control, in bone metabolism. This book concludes by summarising the association between hypertension and osteoporosis in a comprehensive literature review.
Ageing is the accumulation of changes in an organism or object over time. Ageing in humans refers to a multidimensional process of physical, psychological, and social change. Some dimensions of ageing grow and expand over time, while others decline. Reaction time, for example, may slow with age, while knowledge of world events and wisdom may expand. Research shows that even late in life potential exists for physical, mental, and social growth and development. Ageing is an important part of all human societies reflecting the biological changes that occur, but also reflecting cultural and societal conventions. More people are reaching older age today than ever before and the incidence of dementia is thus expected to rise. It is important to investigate the possible prevention of dementia and cognitive decline. This new book gathers the latest research from around the globe in this field of study and related topics such as cardiovascular disease and cognitive function, physical exercise and cognitive function in the elderly, the dementia diagnosis, the role of MRI in Alzheimer's disease, oestrogen decline effects on the mental health of ageing women and the relationship between dementia and depression.
Ageing or aging is the accumulation of changes in an organism or object over time. Ageing in humans refers to a multidimensional process of physical, psychological, and social change. Some dimensions of ageing grow and expand over time, while others decline. Reaction time, for example, may slow with age, while knowledge of world events and wisdom may expand. Research shows that even late in life potential exists for physical, mental, and social growth and development. Ageing is an important part of all human societies reflecting the biological changes that occur, but also reflecting cultural and societal conventions. This book examines several important issues in the field.
The word longevity is sometimes used as a synonym for "life expectancy" in demography. Aging is the accumulation of changes in an organism or object over time. Aging in humans refers to a multidimensional process of physical, psychological, and social change. Some dimensions of aging grow and expand over time, while others decline. Reaction time, for example, may slow with age, while knowledge of world events and wisdom may expand. Research shows that even late in life potential exists for physical, mental, and social growth and development. Aging is an important part of all human societies reflecting the biological changes that occur, but also reflecting cultural and societal conventions. Age is usually measured in full years -- and months for young children. At present, the biological basis of aging is unknown. This book presents the latest research in this dynamic field.
Ageing is any change in an organism over time. Ageing refers to a multidimensional process of physical, psychological, and social change. Some dimensions of ageing grow and expand over time, while others decline. Reaction time, for example, may slow with age, while knowledge of world events and wisdom may expand. Research shows that even late in life potential exists for physical, mental, and social growth and development. Ageing is an important part of all human societies reflecting the biological changes that occur, but also reflecting cultural and societal conventions.
The ageing process changes body composition and thus nutritional status changes as one gets older. At the same time the body becomes more susceptible to diseases and diet becomes an even more significant or at least visibly significant than in earlier years. Moreover, there is frequently socio-economic downward drifting in this age group making nutritious foods more difficult to afford. This book presents the latest research in this vital field.
Book & CD. One of the most striking demographic changes over the last century in Western countries has been the rapid growth, both absolute and relative, of the oldest-old population, to such an extent that living beyond the age of 80 years constitutes a new stage of life. But what is life like after 80? Rather than scrutinizing the pathologies of very old age, this book enquires into the normal aging of the oldest old, their health trajectories, their socio-demographic inequalities; it analyses their daily life, including their social relationships, social support, and activities, and observes how the oldest old adapt to the multiple stresses and challenges of very old age. The book reports major results obtained from Swilsoo, a long-term longitudinal study based on two cohorts of octogenarians. The two cohorts were assessed on an approximately yearly basis, the first for 9 waves from 1994 to 2004, with 340 participants at inception, and the second for 5 waves from 19v9 to 2004, initially with 377 participants. The book demonstrates that many common stereotypes concerning the oldest old are false. For examples, their main shared characteristic is not sickness, but frailty, which affects them in different ways. A long life does not necessarily culminate in dependence. Dependence is a risk -- especially among persons of lower socio-economic status -- but not an ineluctable outcome. It also helps to bring out the importance of social and psychological resources in the lives of the oldest old. Although multiple stresses such as negative health-related changes or self-reported bereavements of a loved one often occur in the life of the elderly and affect their health and well-being, the very old can take advantage of various resources or adjustment mechanisms to help preserve their well-being and robustness. The book shows for instance that the preservation by the elderly of a positive and active role within the family is a boon to their health and that the continuation of leisure activities or the effective use of psychological resources counters the negative effects of frailty on well-being.
Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. Vijg critically reviews the concept of genomic instability as a possible universal cause of aging in the context of a new, holistic understanding of genome functioning in complex organisms resulting from recent advances in functional genomics and systems biology. It provides an up-to-date synthesis of current research, as well as a look ahead to the design of strategies to retard or reverse the deleterious effects of aging. This is particularly important in a time when we are urgently trying to unravel the genetic component of aging-related diseases. Moreover, there is a growing public recognition of the imperative of understanding more about the underlying biology of aging, driven by continuing demographic change.
Dementia is a brain disorder that seriously affects a person's ability to carry out daily activities. The most common form of dementia among older people is Alzheimer's Disease (AD), which involves the parts of the brain that control memory, thought and language. Age is the most important known risk factor for AD. The number of people with the disease doubles every 5 years beyond age 65. AD is a slow disease, starting with mild memory loss and ending with severe brain damage. The course the disease takes and how fast changes occur vary from person to person. On average, AD patients live from 8 to 10 years after they are diagnosed, though the disease can last for as many as 20 years. Current research is aimed at understanding why AD occurs and who is at greatest risk for developing it, improving the accuracy of diagnosis and ability to identify who is at risk, developing, discovering and testing new treatments for behavioural problems in patients with AD. This book gathers state-of-the-art research from leading scientists throughout the world which offers important information on understanding the underlying causes and discovering the most effective treatments for Alzheimer's Disease.
The progressive ageing of the general population and the consequent increase of the number of old people has made the typical medical problems of aged people more frequently observed, and particularly the problems related to the ageing brain. This new book is an updated overview of relevant aspects of cognitive decline associated with ageing. Within the wide landscape of brain ageing the authors reconsider the role of the main predisposing factors and risk factors on the development of various form of mental decline, from mild cognitive impairment to dementia. The strength of this book is the large, updated overview of the most recent data of scientific literature regarding the role of genetic, metabolic and environmental factors on the predisposition and onset of cognitive decline. Particular attention is paid to the dietary micro- and macronutrients and to their possible role in the pathogenesis of the various form of dementigen disorders.
Providing a comprehensive overview of issues of ageing from a global perspective this ambitious text introduces the reader to a wide range of issues and policies on ageing. Topics examined include: theoretical perspectives on ageing in society; demographic trends; roles played by older people as political actors; migration; health; pensions; family and institutional care; and elder abuse. This will be an essential text for students of social gerontology, as well as an invaluable resource for students of nursing, social work, social policy and development studies.
It can slowly drain the life force from your body over time. Or kill swiftly without warning. But you will never find it on a medical chart or see it listed on a death certificate. It's called stress. It exacts a tremendous toll on our lives. It saps our strength, robs our youth and makes us old before our time. We encounter it day in and day out, yet do little, if anything about it. It's no wonder. In today's 'pressure cooker society', the average lunch hour lasts about 11 minutes. Dinner is often consumed in less than 6 minutes (usually seated in front of the television). The average workday can last 10 hours or more. We seem to be living in a society where there's virtually no time for quality time. Strictly speaking, stress itself is not among the direct causes of ageing, yet it plays an extremely important role in the ageing process. It is a powerful force that serves as a catalyst in every known mechanism that causes us to age. Readers might be surprised to find out that this book has as much to do with ageing, life extension and specific measures we can take to postpone the inevitable as it does with stress. The fact is that stress and ageing are inextricably bound together.
The University of Florida has an ambitious goal: to harness the power of its faculty, staff, students, and alumni to solve some of society's most pressing problems and to become a resource for the state of Florida, the nation, and the world. In the upcoming decades, an unprecedented demographic shift will take place; the eighty-five and over population is projected to climb far higher than any other age group. To keep the current elderly population healthy and help prevent future generations from experiencing poor health outcomes, researchers are studying crucial connections between skeletal muscles and whole-body health. The University of Florida is at the forefront of this research, utilizing its nationally recognized excellence in the fields of muscle biology and exercise physiology to discover unique ways to preserve muscle health in the aging and those with diseases. Find out how the proteins within muscle can be manipulated to reduce recovery times for individuals who are bedridden. Learn how older, elite athletes have resisted the inevitable degeneration that comes with aging, and how intermittent fasting may help you live longer and healthier. Step inside the lab where a researcher is uncovering the origins of cancer cachexia a wasting syndrome responsible for 20 percent of cancer deaths worldwide to improve the lives of patients. The loss of skeletal muscle through disease, disuse, or aging is associated with a host of poor health outcomes, but promising new avenues of research are being studied every day at the University of Florida to make for a healthier tomorrow.
Recent research findings on the impact of nutrition on telomere length is unlocking the potential to combat premature aging at the cellular level. We have learned that while aging is a natural cellular process, premature aging is not and it can be positively impacted by an Evidence-Based Proactive Nutrition to Slow Cellular Aging diet plan. This book examines key elements of the biology of cell aging and focuses on enhancing mitochondrial function and preventing abnormal cell turnover thus preserving telomere length. It details the cellular damage caused by free radicals and ROS, explains the salutary effects of antioxidants, and the body's need for adequate nitrates and other nutrient substrates from which the body derives nitric oxide (NO) to support cardiovascular health. This book is the first to feature a simple do-it-yourself test of the effects of the diet on the availability of NO for - heart health. The book guides the reader through the rationale for a modified Mediterranean style diet that supplies the body with an adequate daily intake of essential nutrients, simple high antioxidants, and other functional foods. It includes simple, easy to prepare appealing recipes promoting a seamless transition to a healthy, age-defying lifestyle.
Although books exist on the evolution of aging, this is the first book written from the perspective of again as an adaptive program. It offers an insight into the implications of research on aging genetics, The author proposes the Demographic Theory of Senescence, whereby aging has been affirmatively selected because it levels the death rate over time helping stabilize population dynamics and prevent extinctions.
When confronted with a neurological or psychiatric disorder in an elderly individual, a clinician or researcher is likely to ask how the processes of ageing have influenced the aetiology and presentation of the disorder, and will impact on its efficient management. There are many urban myths about ageing, and some of these apply to the brain. The reviews included in this book are an attempt to flush out some of these myths, and arm the clinician and general researcher with the empirical facts that can be mustered to substantiate claims about ageing. There are many salient questions: is cognitive change to be expected in an elderly individual? Is this change progressive, relentless and unselective, or is it focal and constrained? Would every person who lived long enough develop Alzheimer s disease? Do our neurones die as we get old? What happens to the size of the brain and its metabolic activity? How do our hormones change with age? Can anti-oxidants slow or even stop the process of ageing? Are genes important in the ageing brain or is it all in the environment? How much of what we are is due to what we eat? The contributors to this book, each an expert in their field, have addressed some of these questions in a language simple enough for a general reader to understand. The book also deals with some of the most prominent brain disorders of old age - Alzheimer's disease, Parkinson's disease, vascular dementia, and depression. The focus is on the impact of ageing on these disorders. The discussions lay out a broad map for the clinician dealing with neuropsychiatric disorders, and the future researcher of brain ageing. In a field in which the developments are too numerous for any one individual to keep pace with, this book presents up-to-date summaries that can be a useful starting point. The field of brain ageing abounds in tabloid science. This book counters this by providing a strong empirical grounding and considered synthesis of the research."
The past century has witnessed a revolution. Less than a hundred years ago, the average Western life expectancy was 40; now it is 80. And there is no end in sight: the first person who will reach 135 has already been born. It's the most radical change in our society since industrialisation, and naturally it raises many questions. What do longer life spans mean for the way we organise our societies? How can people best prepare themselves for living considerably longer? Does it help to eat less, or to take hormones, vitamins, or minerals? And what can we learn from old people who remain full of vitality, despite illness and infirmity? Growing Older without Feeling Old is the definitive book on a key issue for the 21st century, written by one of the world's leading experts in geriatric medicine. Combining medical, biological, economic, and sociological insights, Rudi Westendorp explores the causes of the ageing revolution and explains how we can greet it with confidence and enjoy leading longer, healthier, and more productive lives than ever before. |
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