In recent years, remarkable discoveries have been made concerning the underlying mechanisms of aging. In Life-Span Extension: Single-Cell Organisms to Man, the editors bring together a range of illuminating perspectives from researchers investigating the aging process in a variety of species. This novel work addresses the aging process in species ranging from yeast to man and, among other subjects, features detailed discussions of the naked mole-rat, an exceptionally long-lived rodent; the relationship between dietary factors/food restriction and aging; and an evolutionary view of the human aging process.

Single mutations that extend life span have been identified in yeast, worms, flies, and mice, whereas studies in humans have identified potentially important markers for successful aging. At the same time, it has been discovered that the genes and pathways identified in these studies involve a surprisingly small set of conserved functions, most of which have been the focus of aging research for some time. For example, the mTOR pathway, a regulator of translation and protein synthesis, has been identified as a common longevity pathway in yeast and Caenorhabditis elegans. In mammals, this pathway intersects with neuroendocrine pathways and with the insulin/insulin-like growth factor pathways, which have been identified as major modulators of life span and aging in both invertebrates and mice.

Novel, emerging technologies and the increasingly wide variety of systems that are now used to study aging and the mechanisms of aging provide enormous opportunities for the identification of common pathways that modulate longevity. It is these common pathways that are the focus of this important volume.

The United Nations Madrid International Plan of Action on Ageing (MIPAA) offers a bold new agenda for handling the issue of ageing in the 21st-century. It focuses on three priority areas: older persons and development; advancing health and well-being into old age; and ensuring enabling and supportive environments. This book brings together global perspectives on the MIPAA and focusses on and assesses the success and failures of governments to implement its recommendations. Despite its pivotal importance in international ageing policy, the MIPAA has been relatively neglected by academics in their writings and studies. This book mitigates this analytical and empirical cavity. Each chapter focuses on one specific geographical region and addresses five key themes: National ageing situation; Twenty years of MIPAA; Ensuring ageing with dignity; Healthy and active ageing in a sustainable world; and Priorities for the future. It presents an overall summary of the findings, future challenges and opportunities related to ageing, recommendations for future actions to be taken, and policy adjustments needed. The authors also present lessons that were learnt from managing the impact of COVID-19 on older people, together with an outlook on the most immediate priorities for the future so that the recommendations in the MIPAA are achieved in post-COVID-19 and sustainable ethical scenarios. An important contribution towards the advancement of ageing policy, the book will be indispensable to students and researchers of gerontology, ageing, and health. It will also be of interest to policy makers, geriatricians, dementia care specialists, social policy makers responsible for ensuring active and healthy ageing, and all public sector departments which have specific responsibilities towards improving the quality of life of older adults.

This book brings together in one volume the current state of ageing research in the nematode Caenorhabditis elegans. The authors are leading researchers in the field, placing this topic in the context of human ageing, describing how and why basic discoveries in this simple organism have impacted our prospects for intervention in the ageing process. The authors cover a broad range of topics with regards to organismal and reproductive ageing including anatomical, physiological and biochemical changes, as well as genetic and environmental interventions that promote longevity and ameliorate age-related disease. Ageing is the single most important factor determining the onset of human disease in developed countries. With current worldwide demographic trends indicating that the number of individuals over the age of 65 will continue to rise, it is clear that an understanding of the processes that underpin ageing and age-related disease represents a key challenge in the biomedical sciences. In recent years there have been huge advances in our understanding of the ageing process and many of these have stemmed from genetic analysis of C. elegans. With no analogous book in this subject area this work will be of interest to a wide audience, ranging from academic researchers to the general public.

World-wide migration has an unsettling effect on social structures, especially on aging populations and eldercare. This volume investigates how taken-for-granted roles are challenged, intergenerational relationships transformed, economic ties recalibrated, technological innovations utilized, and spiritual relations pursued and desired, and asks what it means to care at a distance and to age abroad. What it does show is that trans-nationalization of care produces unprecedented convergences of people, objects and spaces that challenge our assumptions about the who, how, and where of care.

The conceptualization of dementia has changed dramatically in recent years with the claim that, through early detection and by controlling several risk factors, a prevention of dementia is possible. Although encouraging and providing hope against this feared condition, this claim is open to scrutiny. This volume looks at how this new conceptualization ignores many of the factors which influence a dementia sufferers' prognosis, including their history with education, food and exercise as well as their living in different epistemic cultures. The central aim is to question the concept of prevention and analyze its impact on aging people and aging societies.

Congratulations! You have been given about 20 more years to live than your grandparents. But does that just mean a longer decline? Berit Lewis shows that the story we so often tell ourselves about ageing – that it’s all downhill from 50 – is simply wrong. In fact, research reveals we are at our happiest aged 80! Combining her extensive experience in teaching mindfulness with her knowledge of how to live and age well, she reveals a simple framework that can help you make the most out of those extra years of living. Rather than wait for society to solve the challenges of longevity, she invites us to explore what each of us can do to take responsibility for our own life and ageing process. Ageing Upwards will help you navigate life after 50 with acceptance, self-compassion and mental flexibility. It’s also invaluable to leaders who wants overcome unconscious beliefs, limitations and discriminations related to age to create more diverse organizations.

Women and Positive Aging: An International Perspective presents the noted research in the fields of psychology, gerontology, and gender studies, reflecting the increasingly popular and pervasive positive aging issues of women in today's society from different cohorts, backgrounds, and life situations. Each section describes a bridge between the theoretical aspects and practical applications of the theory that is consistent with the scientist-practitioner training model in psychology, including case studies and associated intervention strategies with older women in each chapter. In addition to incorporating current research on aging women's issues, each section provides the reader with background about the topic to give context and perspective.

'A stunner ... If you haven't got this book in your house, I don't know why' Chris Evans 'A startling wake-up call . . . Writing with the vim of a Bill Bryson and the technical knowledge of a scientist, Steele gives us a chance to grasp what's at stake' Independent 'An exhilarating journey . . . Steele is a superb guide' Telegraph 'A fascinating read with almost every page bursting with extraordinary facts . . . Read it now' Mail on Sunday Ageless is a guide to the biggest issue we all face. Ageing - not cancer, not heart disease - is the world's leading cause of death and suffering. What would the world be like if we could cure it? Living disease-free until the age of 100 is achievable within our lifetimes. In prose that is lucid and full of fascinating facts, Ageless introduces us to the cutting-edge research that is paving the way for this revolution. Computational biologist Andrew Steele explains what occurs biologically as we age, as well as practical ways we can slow down the process. He reveals how understanding the scientific implications of ageing could lead to the greatest discovery in the history of civilisation - one that has the potential to improve billions of lives, save trillions of dollars, and transform the human condition.

Sleeping patterns change with age, whether we are growing up, or growing old. While most people are prepared for the rapidly altering sleep patterns of growing children, the evidence suggests that many are unprepared for additional sleep changes in later life, either in themselves or in others. In this book, originally published in 1987, two research disciplines - social gerontology and sleep research - are brought together with the aim of providing a straightforward account of how sleep is changed and disrupted by the biological and social impact of ageing. Attention then focuses on the personal and clinical response to these changes. The use of sleeping drugs among elderly people is critically examined, and effective alternatives, including self-help practices and psychological therapies, are described. The influence of ageing on the recall and content of dreams is also considered. In the final chapter, the author comments on current styles of responding to sleep problems in old age and discusses the need and the scope for change. This book deals with topics of universal interest and provides valuable information for those professionally as well as personally concerned with sleep quality in later life, including health professionals (nurses, doctors, psychologists etc.) working with elderly people, gerontologists, and sleep researchers.

This book gives an overview of the potential and the practical details that need to be resolved in order to make human germline engineering possible. It presents the ethical and social concerns, and implications of our fast-approaching capability to alter our own germline and take an active role in the future evolution of our own species. It provides explanations of how we have arrived at the capability to clone higher animals, and discusses the implications for human therapies and for our own future when these techniques are applied to the human germline.

This title includes a number of Open Access chapters. Sarcopenia-the loss of muscle mass and strength that occurs with advancing age-is a major health challenge, particularly in North America, Europe, and Japan, which have large aging populations. This compendium volume is a valuable addition to the existing literature, providing state-of-the-art information on the most effective prevention and treatment options. Included are research articles on nutrition management and the prevention of sarcopenia; protein therapy for sarcopenia; effect of exercise on sarcopenia; and other therapeutic strategies, including antioxidants and steroids.

For centuries people have been puzzled by the inevitability of human aging. For most of the second half of the twentieth century aging remained a mystery, or an unsolved biological problem. At the end of the 20th century a remarkable scientific discovery emerged. It was not a single discovery in the usual sense, because it was based on a series of important interconnected insights over quite a long period of time. These insights made it possible for the very first time to understand the biological reasons for aging in animals and man. It can already be said, however, that the many observations and insights that explain aging will not be accepted as established knowledge for a long time. The field is still full of scientists, and non-scientists, who are just happy to go on speculating about the mystery of aging.

The Last Years of Long Lives is a unique account of that period of old age which precedes death. Based on 400 complete individual histories and covering a twenty-year period, it looks at the experiences of people over eighty years old in three important areas: disability, family life and health care. Using the life-course approach to research, it reveals rich data about the contributions of formal and informal care and how life expectancy and experiences of disability interact with experiences of care. The reader is invited to conceptualise these phenomena as processes in continuous time - processes that are sometimes long and complex, sometimes short and simple - and learns about the four types of disability career before death. At the same time, the author presents a three-stage model of informal care and examines the main patterns of formal service use. The Last Years of Long Lives presents a new way of looking at old age for students, researchers, practitioners and policy makers and gives a comprehensive picture of what has been called 'the fourth age'.

This book provides an overview of recent advances in the study of aging and aging related diseases, discussing the topics at individual, organ, tissue, cell, and molecular levels. It also presents studies on the biomarkers of aging and anti-aging interventions. Aging has been becoming a global health problem. However it was not possible to determine aging as we usually diagnose a disease because there are few biomarkers for age estimation. Since ancient times, people have been seeking anti-aging substances and methods for achieving immortality, while the scientific study of aging has only existed for 100 years. This book appeals to researchers both in institutes and in pharmaceutical companies interested in further studies in this field.

Wisdom Mind is a scientifically tested mindfulness program for older adults - those who are cognitively healthy, as well as those who may be experiencing what is referred to as subjective cognitive decline. While mindfulness is already known to benefit a wide variety of individuals, the unique strengths of this program are the ways in which it is tailored specifically to older adults. Session content is keyed to common concerns of older adults (such as cognitive slip-ups, loss, and grief), and incorporates strategies for building upon mindfulness practices in a sequence of increasing difficulty as well as strategies to promote learning and integration. Designed to be used alongside the companion Facilitator Guide, this session-by-session Participant Workbook provides detailed information on how to take part in the program, as well as the reasoning behind why certain practices and strategies are provided at different times and in different ways. As such, it will be of interest to those familiar with mindfulness as well as those new to the practice. A companion website provides downloadable meditation audio recordings that participants can access throughout the program.

In Male Mid-Life Crisis, Justin K. Lim investigates this phase of human life through the perspectives of analytical psychology and through existential theology. Research suggests 80 percent of men suffer from this crisis, and that it is not limited to any culture or period of history. He applies his findings to pastoral/spiritual interventions, seeking deeper and broader psychological and theological insights.

Western thought traditionally divides the human being into a body-mind dualism, a divide realized in the divergent research fields of geriatrics and gerontology; the first examines the physical body, and the second focuses instead upon psychological and social aspects of aging. Research Health Scientist Christopher Faircloth's edited volume of original pieces attempts to bridge this rift: reinserting the physical aging body and its lived experiences back into gerontology's study of aging. He asks, 'Is it not the physical body that readily marks us as aging?' Faircloth organizes this text around two major themes of the aging body: everyday experience, and the social and personal impact of its imagery, while concentrating on three areas of substantive concern: medicalization, gender/sexuality, and the body as consumer. This book would be of interest to gerontologists, social scientists, and students of these fields concerned with the aging body, both object and subject, as experienced and alternatively perceived in relation to contemporary society.

In the twentieth century, all developed nations began to undergo unprecedented demographic changes, as their birth rates declined, and life expectancies increased significantly --an average of thirty years in less than a century. These developments have caused major transformations in the composition of populations in these countries, especially in terms of the proportions of the various age groups. While the age groups of children and adolescents have decreased, those of elderly persons aged 65 and over, have increased.

Consistent with the situation in other developed nations, the absolute number and percentage of elderly persons in the Israeli population is increasing, while the percentage of younger persons is decreasing. Israel, however, differs from other developed countries in the pace of this demographic change, the composition of its population, and the ways it can address needs related to aging. The demographic figures in Israel indicate that not only is the proportion of elderly persons in the total population growing, but that the old population itself is rapidly aging as well.

This volume exemplifies how social science research can promote knowledge about and understanding of needs and opportunities for adaptation, and assist in evaluating the outcomes of policies and services on the personal, community and national levels, as well as suggest required changes. The variety of topics covered in this volume on age-related research, policies and practice reflects a wide range of research by Israeli scholars on social aspects of aging. Their research offers a glimpse into the knowledge base that has been built over the years on the aging process in Israel, the population of elderly people, and the national policies and network of services for the aged. Other developed countries with aging populations have much to learn from the Israeli experience.

In the twentieth century, all developed nations began to undergo unprecedented demographic changes, as their birth rates declined, and life expectancies increased significantly --an average of thirty years in less than a century. These developments have caused major transformations in the composition of populations in these countries, especially in terms of the proportions of the various age groups. While the age groups of children and adolescents have decreased, those of elderly persons aged 65 and over, have increased.

Consistent with the situation in other developed nations, the absolute number and percentage of elderly persons in the Israeli population is increasing, while the percentage of younger persons is decreasing. Israel, however, differs from other developed countries in the pace of this demographic change, the composition of its population, and the ways it can address needs related to aging. The demographic figures in Israel indicate that not only is the proportion of elderly persons in the total population growing, but that the old population itself is rapidly aging as well.

This volume exemplifies how social science research can promote knowledge about and understanding of needs and opportunities for adaptation, and assist in evaluating the outcomes of policies and services on the personal, community and national levels, as well as suggest required changes. The variety of topics covered in this volume on age-related research, policies and practice reflects a wide range of research by Israeli scholars on social aspects of aging. Their research offers a glimpse into the knowledge base that has been built over the years on the aging process in Israel, the population of elderly people, and the national policies and network of services for the aged. Other developed countries with aging populations have much to learn from the Israeli experience.

Based on the "Pathways to Life Quality" longitudinal research study, this book explores the ways in which older adults' residential choices impact their health and well-being. The study examines the factors associated with life quality for persons living on their own in the local community, as well as those in various housing arrangements such as a continuing care retirement facility, adult home, income-subsidized housing, and senior apartments. Topics include plans and adjustment to moving; role identities; social relationships, participation, and integration; health and activity patterns; and coping with life events.

Although attitudes toward the aged and their care are inherent in any society, gerontology itself is a relatively recent field of study and practice. "Gerontology and the Construction of Old Age" applies the methods of discourse analysis and textual analysis to texts and documents in this newly evolved and eclectic fi eld. Green explores and identifies the literary methods and discursive regularities through which aging and the aged have been made into objects of study and treatment, and which together form a mode of knowledge production that will infl uence future texts in the field.

Because such formats of representation limit rational diagnoses of problems and rational courses of ameliorative action, policy implications in the fi eld of gerontology are a major interest of this study. Another interest is methodological. Within the broader constructionist approach to social reality, Green takes the position of "constitutive realism" the notion that social reality is linguistically constructed, primarily in speech and writing.

The book's two aims are to describe analytically the fi eld of gerontology. The field is important both for its growing academic presence and for its practical eff ects on discourse and policy concerning old age. It also hopes to help develop possibilities of inquiry associated with the linguistic, literary, and rhetorical turns of social science in recent years. "Gerontology and the Construction of Old Age" is a substantive investigation, at considerable theoretical depth, of gerontology itself, as well as a methodological treatise with broader implications for social science as it focuses upon the discourse of various professional fields.

The fastest growing demographic in both developed and developing societies around the world, the elderly bring unique medical and financial health-care burdens. In response to this phenomenon, a large and growing body of research is directed toward the science of healthy aging. A substantial amount of observational data points to the consumption of a plant-based diet as a factor in lowering the risk of multiple chronic degenerative age-related diseases. The 6th International Phytochemical Conference, Phytochemicals: Aging and Health, focused on the particular concerns of nutrition in the aging population, as well as new aspects of research methodology, real-world applications, and updates or expansions of previously introduced topics. Drawn from the illustrious panel of scientists and researchers who spoke at the conference, Phytochemicals: Aging and Health begins by highlighting the prevailing theories on aging, including dietary manipulation and the role of phytochemical medicinals or supplements in health. Contributions present state-of-the-art methodologies for polyphenolic analysis, bioavailability, and metabolism-crucial tools that answer pressing questions such as "are there age related changes in flavonoid bioavailability?" The following chapters provide research results on botanicals and inflammation, green tea formulations and skin health, and the effects of phytochemicals on vision, brain function, and cardiovascular disease. The book concludes with forward-looking discussions on applying nutrient-gene interaction research findings to individual dietary recommendations, along with the step-by-step process to commercialize botanical products for allergy relief. Continuing to introduce the highest-quality, groundbreaking research, Phytochemicals: Aging and Health provides pragmatic information for food companies, supplement manufacturers, and researchers interested in developing functional foods and nutraceuticals for the aging population.

Written by Caleb Finch, one of the leading scientists of our time, The Biology of Human Longevity - Inflammation, Nutrition, and Aging in the Evolution of Lifespans synthesizes several decades of top research on the topic of human aging and longevity particularly on the recent theories of inflammation and its effects on human health. The book expands a number of existing major theories, including the Barker theory of fetal origins of adult disease to consider the role of inflammation and Harmon's free radical theory of aging to include inflammatory damage. Future increases in lifespan are challenged by the obesity epidemic and spreading global infections which may reverse the gains made in lowering inflammatory exposure. This timely and topical book will be of interest to anyone studying aging from any scientific angle.
* Author Caleb Finch is a highly influential and respected scientist, ranked in the top half of the 1% most cited scientists
* Provides a novel synthesis of existing ideas about the biology of longevity and aging
* Incorporates important research findings from several disciplines, including Gerontology, Genomics, Neuroscience, Immunology, Nutrition

Growing old-what is it like? What are the main problems of the aging? Lack of fulfillment in their work and life? Loneliness? Anxiety about sickness and disability? Fear of death? This well-documented, theoretically systematic, and vivid account of the process of aging provides highly enlightening answers and dispels once and for all many of the myths surrounding the close to 20 million Americans who are over sixty-five. Building upon the results of extensive interviews conducted over a period of 5 1/2 years, the authors have developed the concept of "Life Styles," a new method of describing and analyzing the general pattern and course of an individual's life. They have established the existence of six styles and have concluded that a successful transition to old age can be achieved through any of them. They have also developed a definition of success, which has practical implications, since it deals with the extent to which an individual contributes or is a burden to the lives of those around him. The combined analysis of "style" and "success" results in a better understanding of individual differences in aging. The cases are described and analyzed so interestingly and yet methodically that the reader comes to know and understand the subjects as if he had worked with them in person. In addition, the wealth of detail the case histories contain permits scholars and students to judge for themselves the validity of the authors' findings. Derived from this unusually rich body of material, the authors' conclusions and recommendations are invaluable to all concerned with the study, the treatment, and the counseling of the aged. "Lives Through the Years" is a pioneering volume of social inquiry and interpretation, which marks a major scientific advance in its field, opens up new horizons for fruitful research, and offers a stimulating and authoritative portrayal of one of the most important problems of our society. "Richard H. Williams" is Special Assistant to the Director, National Institute of Mental Health. Formerly chief of the Professional Services Branch of the Institute, Dr. Williams is a specialist in psychiatric rehabilitation and mental health aspects of the aging process. "Claudine G. Wirths" is a Consultant at the National Institute of Mental Health. She has served state and city governments and the Department of Defense in various capacities, chiefly as a consulting psychologist. "Talcott Parsons" (1902-1979) was professor of sociology, Harvard University where he set up the Department of Social Relations. He published more than 150 books and articles.

This second edition of the "Handbook of Communication and Aging Research" captures the ever-changing and expanding domain of aging research. Since it was first recognized that there is more to social aging than demography, gerontology has needed a communication perspective. Like the first edition, this handbook sets out to demonstrate that aging is not only an individual process but an interactive one. The study of communication can lead to an understanding of what it means to grow old. We may age physiologically and chronologically, but our social aging--how we behave as social actors toward others, and even how we align ourselves with or come to understand the signs of difference or change as we age--are phenomena achieved primarily through communication experiences.
Synthesizing the vast amount of research that has been published on communication and aging in numerous international outlets over the last three decades, the book's contributors include scholars from North America and the United Kingdom who are active researchers in the perspectives covered in their particular chapter. Many of the chapters work to deny earlier images of aging as involving normative decrement to provide a picture of aging as a process of development involving positive choices and providing new opportunities. A recuring theme in many chapters is that of the heterogeneity of the group of people who are variously categorized as older, aged, elderly, or over 65. The contributors review the literature analytically, in a way that reveals not only current theoretical and methodological approaches to communication and aging research but also sets the future agenda.
This handbook will be of great interestto scholars and researchers in gerontology, developmental psychology, and communication, and, in this updated edition, will continue to play a key role in the study of communication and aging.