Brain Hypoxia and Ischemia explores the various aspects of cell
death and survival that are crucial for understanding the basic
mechanisms underlying brain hypoxia and ischemia. Chapters focus on
a panorama of issues including the role of ion
channels/transporters, mitochondria and apoptotic mechanisms, the
roles of glutamate/NMDA, mechanisms in penumbral cells and the
importance of intermittent hypoxia and gene regulation under these
stressful conditions. The volume explores findings from both
mammalian and invertebrate model systems and their applicability to
human systems and diseases. Careful consideration is also given to
differences in hypoxia and ischemia across development.
This volume aims to increase the understanding of these
mechanisms and to stimulate research on better diagnosis and
treatment of diseases that afflict the brain and potentially other
organs when O2 levels are dysregulated. Brain Hypoxia and Ischemia
is designed for neuroscientists, clinicians and medical/graduate
students for use in both basic research and clinical practice.
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