Cancer Chemoprevention - Volume 1: Promising Cancer Chemopreventive Agents (Hardcover, 2004 ed.)

This is a comprehensive reference survey on the identification and development of promising cancer chemopreventive agents that will help stimulate further novel research and new approvable drugs. For each agent, the authors review the relevant mechanisms of action, the criteria for populations benefiting from intervention, the safety and pharmacodynamics, clinical study design emphasizing the use of precancers, and early associated cellular and molecular biomarkers of carcinogenesis. The pharmacologic and/or mechanistic classes discussed range from antimutagens, antiinflammatories, and the nuclear receptor superfamily, to signal transduction modulators, antioxidants, vitamins, and minerals. The overall focus is on molecular targets and mechanisms. A second volume, "Strategies in Chemoprevention", describes the exciting methodologies that will accelerate progress in this field and discusses the state of clinical development of chemoprevention in the various human cancer target organs.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Cancer Drug Discovery and Development
Release date:	June 2004
First published:	2004
Editors:	Gary J. Kelloff • Ernest T. Hawk • Caroline C. Sigman
Dimensions:	279 x 216 x 44mm (L x W x T)
Format:	Hardcover
Pages:	697
Edition:	2004 ed.
ISBN-13:	978-1-58829-076-2
Categories:	Books > Medicine > Other branches of medicine > Pharmacology > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	1-58829-076-X
Barcode:	9781588290762

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