Leading clinicians and clinical researchers discuss in practical
detail the newest treatments used in rheumatic diseases,
emphasizing-without neglecting current standard treatments-those
experimental therapies now undergoing clinical trials and poised
for early introduction into the rheumatology armamentarium. The
diseases and therapeutic regimes examined here range from
rheumatoid arthritis and its treatment by gene therapy, to
osteoarthritis and systemic autoimune diseases. Each chapter is
organized so that the busy clinician can quickly obtain all the
information needed optimal patient treatment. This includes an
analysis of the pathogenic mechanisms that explain the molecular
basis of the newer therapeutics, reviews of animal data and the
results of clinical trials, and recommendations concerning use,
side effects, and precautions.
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