Mesothelioma - From Research to Clinical Practice (Paperback, 1st ed. 2019)

This book offers an updated review of malignant mesothelioma, including the latest advances in our understanding of its genetic control and molecular biology, as well as pre-clinical and clinical research. It also presents state-of-the-art diagnostic approaches and therapeutic options, and an open discussion on the future prospects for patient management. Malignant mesothelioma is an enormous global health problem related to asbestos exposure. Despite the best efforts of scientists and oncologists, the prognosis for those affected remains poor. Due to anatomical characteristics and non-specific symptoms, the diagnosis of mesothelioma at an early stage is often difficult, while surgery and radiotherapy are only of limited use, even if some multimodality approaches seem promising. In turn, medical treatments are sometimes successful in tumor control, but have little impact on overall survival. However, advances in our understanding of the disease's biology, together with the availability of new drugs and combinations, make mesothelioma an essential and highly topical field for pre-clinical and clinical studies. This book is subdivided into four parts: epidemiology and preclinical data, diagnosis, therapy, and extrathoracic mesothelioma. It highlights the progress made in a variety of areas - e.g. in vitro and in vivo experimental models, genetics, environment, biomarkers, targeting agents, immunotherapy, metabolic imaging and ongoing clinical trials - and describes the standard clinical management of mesothelioma patients, including those with extra-thoracic localizations. Given its scope, the book offers an invaluable tool for researchers, oncologists and clinicians alike.

General

Imprint:	Springer Nature Switzerland AG
Country of origin:	Switzerland
Release date:	August 2020
First published:	2019
Editors:	Giovanni Luca Ceresoli • Emilio Bombardieri • Maurizio D'Incalci
Dimensions:	254 x 178mm (L x W)
Format:	Paperback
Pages:	340
Edition:	1st ed. 2019
ISBN-13:	978-3-03-016886-5
Categories:	Books > Medicine > Clinical & internal medicine > Respiratory medicine Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	3-03-016886-7
Barcode:	9783030168865

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