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Books > Medicine > Pre-clinical medicine: basic sciences > Physiology
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Organic Cation Transporters - Integration of Physiology, Pathology, and Pharmacology (Hardcover, 1st ed. 2016)
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Organic Cation Transporters - Integration of Physiology, Pathology, and Pharmacology (Hardcover, 1st ed. 2016)
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This innovative text explores the cellular transport of organic
cations, from functional and structural properties to
pharmacological implications and psychiatric developments. The
authoritative chapters introduce organic cation transporters and
then proceed to discuss their mechanisms such as binding of
substrates and inhibitors; their drug dispositions and toxicity;
their relationships to genetic and pathophysiological variability;
and their roles in endocrine, metabolic, and neurological systems.
The final chapters delve into the use of animal models for the
study of organic cation transporter function and their possible use
in environmental cycling of pharmaceutical residues. This
comprehensive volume unites integrative transporter physiology with
structural and molecular biology, genetics, pharmacology and
pathophysiology, offering a holistic approach to utilizing this
novel technique in physiological contexts. It will prove invaluable
reading for researchers and students in various areas of
integrative, organ, cell and molecular physiology as well as
pharmacologists and neurologists.
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