Organic Cation Transporters - Integration of Physiology, Pathology, and Pharmacology (Paperback, Softcover reprint of the original 1st ed. 2016)

This innovative text explores the cellular transport of organic cations, from functional and structural properties to pharmacological implications and psychiatric developments. The authoritative chapters introduce organic cation transporters and then proceed to discuss their mechanisms such as binding of substrates and inhibitors; their drug dispositions and toxicity; their relationships to genetic and pathophysiological variability; and their roles in endocrine, metabolic, and neurological systems. The final chapters delve into the use of animal models for the study of organic cation transporter function and their possible use in environmental cycling of pharmaceutical residues. This comprehensive volume unites integrative transporter physiology with structural and molecular biology, genetics, pharmacology and pathophysiology, offering a holistic approach to utilizing this novel technique in physiological contexts. It will prove invaluable reading for researchers and students in various areas of integrative, organ, cell and molecular physiology as well as pharmacologists and neurologists.

General

Imprint:	Springer International Publishing AG
Country of origin:	Switzerland
Release date:	March 2019
First published:	2016
Editors:	Giuliano Ciarimboli • Sophie Gautron • Eberhard Schlatter
Dimensions:	235 x 155mm (L x W)
Format:	Paperback
Pages:	264
Edition:	Softcover reprint of the original 1st ed. 2016
ISBN-13:	978-3-319-79534-8
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > General Books > Medicine > Other branches of medicine > Pathology > Gross pathology Books > Medicine > Other branches of medicine > Pharmacology > General
LSN:	3-319-79534-1
Barcode:	9783319795348

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