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Recent Results of Research on Arteriosclerosis (Paperback, 1988 ed.)
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Recent Results of Research on Arteriosclerosis (Paperback, 1988 ed.)
Series: Sitzungsber.Heidelberg 88, 1988 / 1988/4
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Initiated in 1975, the Eberbach/Wiesloch Study is a prospective
preventive study modeled after the Cardiovascular Comprehensive
Community Central Programme of the WHO, with the aim of lowering
the incidence of cardiac infarctions in a population representative
of that of the Federal Republic of Germany. Part of the study is
devoted to a description of smoking habits, and in particular, of
the effect of cigarette smoking on plasma lipid and lipoprotein
levels. Important components of this investigation were the
inclusion of plasma levels of cotinine (a stable metabolite of
nicotine and the only precise parameter of cigarette consumption),
as well as the correlation of cotinine with other plasma
parameters. Not only are these studies unique in the Federal
Republic of Germany, but they also provide significant insight into
the development of arteriosclerosis in connection with the
established risk factors of smoking and hyperlipidemia. The data
collected point to a considerable influence of smoking behavior on
plasma lipid protein parameters.
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