Homocysteine Metabolism in Health and Disease (Hardcover, 1st ed. 2022)

This book comprehensively reviews the association of homocysteine metabolism with the etiology of various human disorders. The well-defined chapters embedded the central and peripheral effects of homocysteine metabolism intricately related with cardiovascular, neurodegenerative, metabolic, and autoimmune disorders. Further, it discusses the mechanisms of perturbance of cellular proteostasis by elevated homocysteine levels and provides a comprehensive account of pathophysiological consequences and clinical implications of homocysteine-containing proteins. The book also reviews association of genetic variants of homocysteine metabolic genes with type 2 diabetes mellitus and obesity. It also describes the molecular mechanism of hyperhomocysteinemia in the negative/feedback regulation of neural stem cell proliferation and alterations in DNA methylation. Taken together, it summarizes the mechanisms of hyper homocysteinemia-induced endothelial dysfunction and physiological functions of hydrogen sulfide as the protective agent.

General

Imprint:	Springer Verlag, Singapore
Country of origin:	Singapore
Release date:	May 2022
First published:	2022
Editors:	Govind Prasad Dubey • Krishna Misra • Rajesh K. Kesharwani • Rudra P. Ojha
Dimensions:	235 x 155mm (L x W)
Format:	Hardcover
Pages:	276
Edition:	1st ed. 2022
ISBN-13:	978-981-16-6866-1
Categories:	Books > Science & Mathematics > Chemistry > General Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > General Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical) > General Promotions
LSN:	981-16-6866-3
Barcode:	9789811668661

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