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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences
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Homocysteine Metabolism in Health and Disease (Hardcover, 1st ed. 2022)
Loot Price: R4,943
Discovery Miles 49 430
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Homocysteine Metabolism in Health and Disease (Hardcover, 1st ed. 2022)
Expected to ship within 12 - 17 working days
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This book comprehensively reviews the association of homocysteine
metabolism with the etiology of various human disorders. The
well-defined chapters embedded the central and peripheral effects
of homocysteine metabolism intricately related with cardiovascular,
neurodegenerative, metabolic, and autoimmune disorders. Further, it
discusses the mechanisms of perturbance of cellular proteostasis by
elevated homocysteine levels and provides a comprehensive account
of pathophysiological consequences and clinical implications of
homocysteine-containing proteins. The book also reviews association
of genetic variants of homocysteine metabolic genes with type 2
diabetes mellitus and obesity. It also describes the molecular
mechanism of hyperhomocysteinemia in the negative/feedback
regulation of neural stem cell proliferation and alterations in DNA
methylation. Taken together, it summarizes the mechanisms of hyper
homocysteinemia-induced endothelial dysfunction and physiological
functions of hydrogen sulfide as the protective agent.
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