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Metabolic Changes Induced by Alcohol (Paperback)
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Metabolic Changes Induced by Alcohol (Paperback)
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In nearly all parts of the world, the consumption of alcohol is
increasing, and the morbidity and mortality of diseases induced by
alcohol are rising correspondingly. It has been stated that alcohol
is consumed because it pro duces intoxication. This effect is due
to its toxicological influence on the central nervous system with
the resulting functional disturbances. For many years, the concept
that alcoholic liver disease was of nutritional origin and only
indirectly related to alcohol consumption and metabolism was
accepted. Opinion has changed gradually in recent years and tends
now to regard alcohol itself through its combustion, as responsible
for many metabolic disorders. Interest in this problem has
increased during the past decade, and numerous papers bearing on
this subject have appeared. It seems that the oxidation of alcohol
in the liver interferes in many ways with the intermediary
metabolism of lipids, carbohydrates and proteins, including enzymes
and hormones, and exerts damaging influence on the liver, the
musculature, the heart, the brain and the kidneys. The "Workshop
Symposium" brought together a limited number of the scientists
involved in the new development, biochemists, physiologists,
pharmacologists, pathologists and clinicians from eight European
countries and from the United States and allowed a very lively and
informal exchange. The symposium was honored by the presence of Sir
Hans Krebs, whose vast experience stimulated the discussion. It is
a great pleasure to dedicate this volume to Sir Hans on the
occasion of his 70th birthday on August 25th."
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