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Books > Medicine > Clinical & internal medicine > Endocrinology > Diabetes
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Incretin Biology - A Practical Guide: Glp-1 And Gip Physiology (Hardcover)
Loot Price: R2,815
Discovery Miles 28 150
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Incretin Biology - A Practical Guide: Glp-1 And Gip Physiology (Hardcover)
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Together, obesity and diabetes form a 21st century epidemic, the
treatment of which consumes a substantial fraction of global health
costs. New and improved therapies are therefore desperately
needed.Incretins are short peptide hormones released from the gut
in response to food transit. These hormones regulate a plethora of
processes to control food intake, body weight and glucose
homeostasis. This is one of the fastest areas of growth within
diabetes research, and over the past decade, increasing numbers of
novel diabetes drugs - many based on incretin action - have been
added to the therapeutic armoury.Following an introduction
detailing the historical perspective and discovery of incretin
therapies and clinical applications, the book looks at the release
of incretins at a cellular level from entero-endocrine cells, and
actions on the pancreas (alpha and beta cells) and brain. It then
looks at changes in incretins seen in diabetes and following
bariatric surgery. Finally, the side effects of incretin therapy
are discussed. Importantly, each chapter contains a methodology
section aimed at providing a practical guide to key techniques in
the field of incretin biology and ranges from basic laboratory
research to clinical practice.Incretin Biology - A Practical Guide
offers a unique perspective within this field of research by
bringing together scientists, physicians and bariatric surgeons.
Thus, it is a comprehensive text that offers a broad overview of
the subject.
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