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Books > Medicine > Clinical & internal medicine > Gynaecology & obstetrics
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Issues and Reviews in Teratology - Volume 5 (Paperback, Softcover reprint of the original 1st ed. 1990)
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Issues and Reviews in Teratology - Volume 5 (Paperback, Softcover reprint of the original 1st ed. 1990)
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Why Efforts to Expand the Meaning of "Teratogen" Are Unacceptable
Disagreement about nomenclature in teratology is not new. Dissent
even about the very fabric of the discipline-what congenital
malformations consist of-has often been voiced. Time, instead of
resolving such diffi culties, has sometimes worsened them. For
example, in the past it was agreed that congenital malforma tions
are abnormalities of structure present at birth, but differences of
opinion concerning where the line between normal and abnormal was
to be drawn prevailed. It was obvious that, in order to discover
the causes of congenital malformations and cast strategies for
their prevention, it would be necessary to have knowledge of the
baseline of their frequency, and that this required uniformity of
definition of terms. Since malfor mations of primary social concern
are those having grave outcomes (and are, paradoxically, also the
commonest ones), it is logical that such condi tions were the first
consideration of investigators and were the defects whose frequency
was considered to comprise the required baseline.
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