Although pancreatic cancer is one of the most serious forms of
cancers, the outlook for patients could be improved. The lack of
clinical symptoms of early, surgically removable disease most often
limits curative treatment options. The aggressive tumor cell
biology, leading to a locally advanced nature of the disease and to
early metastases, allows curative resection in only 20% of patients
at the time of diagnosis. Patients are therefore often faced with a
dreadful prognosis from a state of almost full physical health.
Furthermore, because there is a high recurrence rate after curative
resection, treatment of this tumor entity becomes a great
challenge.
This book gives insight into the current understanding of the
management of pancreatic cancer and considers recent findings in
cancer research. It provides answers to questions of how to know
when cancer is respectable, how to proceed when the diagnosis comes
too late for a curative approach, and how to assess different study
results. Moreover, it highlights new upcoming therapeutic options
and experimental approaches, which might further improve the future
prospects for patients with pancreatic adenocarcinoma.
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