Immune Mechanisms of Pain and Analgesia is the first volume to
discuss a new concept of immune-neural interplays leading to pain
or analgesia. It argues the classical view that pain and its
control are restricted to the nervous system, offering a
comprehensive overview of the emerging area of immune mechanisms in
pain and its control. It challenges the traditional view that pain
sensation or suppression is attributed exclusively to the nervous
system and presents a critical analysis of this new concept. The
book is written by an internationally recognized group of
researchers and discusses complex and controversial issues such as
cytokines and their pain-exacerbating but also analgesic effects,
the production of opioids by immune cells, peripheral analgesic and
anti-inflammatory actions of opioids, immunomodulatory effects of
opiates, and immunosuppressive effects of pain.
General
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