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Books > Science & Mathematics > Chemistry > Organic chemistry > Polymer chemistry
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-Aminoacid-N-Carboxy-Anhydrides and Related Heterocycles - Syntheses, Properties, Peptide Synthesis, Polymerization (Paperback, Softcover reprint of the original 1st ed. 1987)
Loot Price: R2,945
Discovery Miles 29 450
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-Aminoacid-N-Carboxy-Anhydrides and Related Heterocycles - Syntheses, Properties, Peptide Synthesis, Polymerization (Paperback, Softcover reprint of the original 1st ed. 1987)
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In 1906, Hermann Leuchs, a student of Emil Fischer, discovered the
class of N-Carboxy-aminoacid-anhydrides, also known as Leuch's
anhydrides, or abbreviated NCAs. These compounds are, even 80 years
after their discovery, valuable intermediates in organic synthesis
due to their reactivity: NCAs polymerize with the elimination of
carbondioxide to yield polypeptides, model compounds for proteins.
They can be used as starting material for a variety of
pharmaceutically interesting products and for synthetic polymers
(fibres and films). Ralph Hirschmann demonstrated the step by step
synthesis of ribonuclease utilizing NCAs as monomers. The author of
this monograph, Hans R. Kricheldorf, University Hamburg, is, on
account of his own research in Freiburg and Hamburg, predestined to
give the reader an insight into the organic chemistry of NCAs and
related heterocycles as well as macromolecular chemistry, that is
the synthesis of polypeptides and the structure-reactivity
relationship. I predict a good accept- ance of this book about the
class of cyclic aminoacid derivatives by scientists in various
areas. Aachen, September 1986 Helmut Zahn Acknowledgment The author
would like to express his gratitude to the american chemical
society, the royal society of chemistry, Marcel Dekker Inc., John
Wiley & Sons, Hiithig & Wepf Verlag and Kobunshi Gakkai for
the permission to reproduce figures from their journals.
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