It was probably the French chemist Portes, who first reported in
1880 that the mucin in the vitreous body, which he named
hyalomucine, behaved differently from other mucoids in cornea and
cartilage. Fifty four years later Karl Meyer isolated a new
polysaccharide from the vitreous, which he named hyaluronic acid.
Today its official name is hyaluronan, and modern-day research on
this polysaccharide continues to grow.
Expertly written by leading scientists in the field, this book
provides readers with a broad, yet detailed review of the chemistry
of hyaluronan, and the role it plays in human biology and
pathology. Twenty-seven chapters present a sequence leading from
the chemistry and biochemistry of hyaluronan, followed by its role
in various pathological conditions, to modified hylauronans as
potential therapeutic agents and finally to the functional,
structural and biological properties of hyaluronidases. Chemistry
and Biology of Hyaluronan covers the many interesting facets of
this fascinating molecule, and all chapters are intended to reach
the wider research community.
* Comprehensive look at the chemistry and biology of
hyaluronans
* sential to Chemists, Biochemists and Medical researchers
* broad yet detailed review of this rapidly growing research
area
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