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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Oxidative Stress and Inflammatory Mechanisms in Obesity, Diabetes, and the Metabolic Syndrome (Paperback)
Loot Price: R1,843
Discovery Miles 18 430
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Oxidative Stress and Inflammatory Mechanisms in Obesity, Diabetes, and the Metabolic Syndrome (Paperback)
Expected to ship within 12 - 17 working days
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Characterized by obesity, insulin resistance, dyslipidemia, and
hypertension, metabolic syndrome is associated with the risks of
type 2 diabetes mellitus and cardiovascular disease. Obesity, which
increases the incidence of atherosclerotic cardiovascular disease
and subsequently leads to increased stress and inflammation,
appears to play a central role in the progression of the syndrome.
Evidence of inflammatory processes in accumulated fat appears to be
an early initiator of metabolic syndrome. Likewise, the more active
angiotensin system in obesity may contribute to even greater
oxidative stress that serves as a key signaling event in vascular
remodeling. These factors strengthen obesity's association with
oxidative stress. Oxidative Stress and Inflammatory Mechanisms in
Obesity, Diabetes, and the Metabolic Syndrome is designed to
encourage the development of evidence-based nutritional and
pharmacological therapies that can attenuate the impact of
obesity-induced insulin resistance and ensuing metabolic syndrome.
The book offers a deep understanding of the molecular mechanisms
that underlie the process. Edited by leading authorities on
oxidative stress, the book's chapters report on cutting-edge
research that explores intracellular events mediating or preventing
oxidative stress and pro-inflammatory processes in obesity and type
2 diabetes. It also brings together research on the molecular
mechanisms inherent in the progression of metabolic stress,
includes phenotypic perspectives, and discusses dietary factors,
including the role of micronutrients. The chapter authors, each a
leading expert in his or her field, discuss different components of
metabolic stress and obesity and their associations with oxidative
stress and inflammation. The book fills a unique role as a base of
knowledge for researchers seeking to develop nutritional and or
pharmacological therapies, as well as clinicians seeking a better
understanding of this increasingly common dis
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