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Horisons in Cancer Research - Volume 61 (Hardcover)
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Horisons in Cancer Research - Volume 61 (Hardcover)
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This book presents original results on the leading edge of cancer
research. Chapter One explains unanswered questions of contemporary
oncology from the standpoint of karyogamic theory of
carcinogenesis. Chapter Two focuses on the molecular players of the
human papillomaviruses (HPVs) infection leading to chronic
inflammation and cancer. Chapter Three describes Multiple Myeloma
(MM), and Monoclonal Gammopathy of Undetermined Significance
(MGUS). Chapter Four reviews the role of choline metabolites as
second messengers in cellular pathways leading to enhanced cell
survival, migration, and proliferation to explore the possibility
that "in-vivo" imaging of choline metabolism can be used to obtain
readouts of cell signal transduction in cancer. Chapter Five
investigates the possible correlation between anatomic melanoma
distribution on the specific back area and lack of sunscreen
application. Chapter Six describes the known molecular mechanisms
of epigallocatechin (EGC) and epigallocatechin-3-gallate (EGCG) in
malignant neuroblastoma that can help find new directions for
future research. Chapter Seven discusses the burdens of childhood
cancer survivorship and the consequences of different treatment
therapies on the incidence of CVD and explores potential monitoring
methods and the need for consistent cardiovascular monitoring of
childhood cancer survivors regarding their cardiovascular health.
Finally, Chapter Eight considers a model for implementing
recommendations pertaining to Lynch syndrome, and also looks at
what is happening in the field now to support Lynch syndrome
genetic testing and surveillance, and how a deliberative conference
can point the way to changes that need to take place to deliver
screening to those at risk.
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