This book presents original results on the leading edge of cancer
research. Chapter One summarizes what is currently known regarding
the epigenetic regulation of osteosarcoma pathways and oncogenes,
as well as clinical trials of drugs that exert epigenetic
regulation. Chapter Two critically discusses the role of
ECM-dependent signaling in osteosarcoma progression. Chapter Three
illustrates the harmful effects of ultraviolet radiation exposure
by focusing on photocarcinogenesis. Chapter Four examines the
psychology of sunscreen use and outlines the key psychological
factors associated with sunscreen use. Chapter Five reviews the
cellular and molecular mechanism of Regulatory T cells (Tregs) and
Transforming Growth Factor- mediating cervical cancer development.
Chapter Six examines the affect of the American cranberry extract
on expression of insulin-like growth factor-I and insulin-like
growth factor binding proteins in human prostate cancer cells in
vitro. Chapter Seven discusses the design of synthetic peptides to
specifically interfere the papillomavirus binding factor/14-3-3beta
binding to restore papillomavirus binding factor apoptotic
functions. Chapter Eight examines brain development using
correlations between Diffusion Kurtosis and neurite orientation
dispersion and density imaging (NODDI) in neonates and young
children. Chapter Nine highlights the opportunities that are
available to prevent the late effects related to stress and fears,
emphasizing the importance of teaching patients resiliency and how
to cope.
General
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