Effective treatment of acute myocardial infarction remains one of
the major issues in cardiology and internal medicine. The present
monograph summarizes the relevant experimental data and the results
of major clinical trials in the treatment of myocardial infarction.
There are contributions of fundamental anatomical and physiological
concepts of vascular occlusion and myocardial damage due to
ischemia as well as discussions of therapeutic strategies involving
thrombolytic agents, adjuvant drug therapy for limitation of
myocardial damage, improvement in myocardial tolerance to ischemia
and prevention of coronary reocclusion. In this regard, there is an
extensive discussion of the role of coronary angioplasty and bypass
surgery in the setting of acute myocardial infarction.
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