A Phenomenological Mathematical Modelling Framework for the Degradation of Bioresorbable Composites (Hardcover, 1st ed. 2019)

This book presents a generalised computational model for the degradation of resorbable composites, using analytic expressions to represent the interwoven phenomena present during degradation. It then combines this modelling framework with a comprehensive database of quantitative degradation data mined from existing literature and from novel experiments, to provide new insights into the interrelated factors controlling degradation. Resorbable composites made of biodegradable polyesters and calcium-based ceramics have significant therapeutic potential as tissue engineering scaffolds, as temporary implants and as drug-loaded matrices for controlled release. However, their degradation is complex and the rate of resorption depends on multiple connected factors such as the shape and size of the device, polymer chemistry and molecular weight, particle phase, size, volume fraction, distribution and pH-dependent dissolution properties. Understanding and ultimately predicting the degradation of resorbable composites is of central importance if we are to fully unlock the promise of these materials.

General

Imprint:	Springer Nature Switzerland AG
Country of origin:	Switzerland
Series:	Springer Theses
Release date:	April 2019
First published:	2019
Authors:	Ismael Moreno-Gomez
Dimensions:	235 x 155mm (L x W)
Format:	Hardcover
Pages:	325
Edition:	1st ed. 2019
ISBN-13:	978-3-03-004989-8
Categories:	Books > Science & Mathematics > Mathematics > Applied mathematics > Mathematical modelling Books > Professional & Technical > Mechanical engineering & materials > Materials science > General Promotions
LSN:	3-03-004989-2
Barcode:	9783030049898

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