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Books > Professional & Technical > Mechanical engineering & materials > Materials science
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A Phenomenological Mathematical Modelling Framework for the Degradation of Bioresorbable Composites (Hardcover, 1st ed. 2019)
Loot Price: R4,060
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A Phenomenological Mathematical Modelling Framework for the Degradation of Bioresorbable Composites (Hardcover, 1st ed. 2019)
Series: Springer Theses
Expected to ship within 18 - 22 working days
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This book presents a generalised computational model for the
degradation of resorbable composites, using analytic expressions to
represent the interwoven phenomena present during degradation. It
then combines this modelling framework with a comprehensive
database of quantitative degradation data mined from existing
literature and from novel experiments, to provide new insights into
the interrelated factors controlling degradation. Resorbable
composites made of biodegradable polyesters and calcium-based
ceramics have significant therapeutic potential as tissue
engineering scaffolds, as temporary implants and as drug-loaded
matrices for controlled release. However, their degradation is
complex and the rate of resorption depends on multiple connected
factors such as the shape and size of the device, polymer chemistry
and molecular weight, particle phase, size, volume fraction,
distribution and pH-dependent dissolution properties. Understanding
and ultimately predicting the degradation of resorbable composites
is of central importance if we are to fully unlock the promise of
these materials.
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