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Books > Science & Mathematics > Physics > Applied physics & special topics > Medical physics
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A Guide to Outcome Modeling In Radiotherapy and Oncology - Listening to the Data (Hardcover)
Loot Price: R4,649
Discovery Miles 46 490
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A Guide to Outcome Modeling In Radiotherapy and Oncology - Listening to the Data (Hardcover)
Series: Series in Medical Physics and Biomedical Engineering
Expected to ship within 12 - 19 working days
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This book explores outcome modeling in cancer from a data-centric
perspective to enable a better understanding of complex treatment
response, to guide the design of advanced clinical trials, and to
aid personalized patient care and improve their quality of life. It
contains coverage of the relevant data sources available for model
construction (panomics), ranging from clinical or preclinical
resources to basic patient and treatment characteristics, medical
imaging (radiomics), and molecular biological markers such as those
involved in genomics, proteomics and metabolomics. It also includes
discussions on the varying methodologies for predictive model
building with analytical and data-driven approaches. This book is
primarily intended to act as a tutorial for newcomers to the field
of outcome modeling, as it includes in-depth how-to recipes on
modeling artistry while providing sufficient instruction on how
such models can approximate the physical and biological realities
of clinical treatment. The book will also be of value to seasoned
practitioners as a reference on the varying aspects of outcome
modeling and their current applications. Features: Covers top-down
approaches applying statistical, machine learning, and big data
analytics and bottom-up approaches using first principles and
multi-scale techniques, including numerical simulations based on
Monte Carlo and automata techniques Provides an overview of the
available software tools and resources for outcome model
development and evaluation, and includes hands-on detailed examples
throughout Presents a diverse selection of the common applications
of outcome modeling in a wide variety of areas: treatment planning
in radiotherapy, chemotherapy and immunotherapy, utility-based and
biomarker applications, particle therapy modeling, oncological
surgery, and the design of adaptive and SMART clinical trials
General
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