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Books > Professional & Technical > Electronics & communications engineering > Electronics engineering > Applied optics > Laser technology
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Novel Optical Endoscopes for Early Cancer Diagnosis and Therapy (Hardcover, 1st ed. 2019)
Loot Price: R2,873
Discovery Miles 28 730
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Novel Optical Endoscopes for Early Cancer Diagnosis and Therapy (Hardcover, 1st ed. 2019)
Series: Springer Theses
Expected to ship within 10 - 15 working days
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This thesis describes the design, development, characterisation and
clinical translation of three novel devices for optical endoscopic
imaging. Over the past decade, rapid innovation in optics and
photonics has led to the availability of low-cost and
high-performance optical technologies that can be exploited for
biomedical applications, but relatively few have been translated
into clinic. The work presented outlines for the first time, a
comprehensive analysis of the common barriers and unique challenges
associated with the translation of optical imaging techniques. To
assist developers streamline translation of optical imaging devices
in future, a roadmap to clinical translation is outlined, and key
translational characteristics are defined. Guided by these,
subsequent development of endoscopic devices resulted in
preparation and approval of endoscopes for first in human trials in
the oesophagus, for early detection of cancer, and in the brain,
for delineation of tumour during surgical resection. The thesis
culminates in the presentation of results from the first in human
use of a compact multispectral endoscope for imaging endogenous
tissue contrast in the oesophagus. With continuation of the work as
outlined at the end of this thesis, the novel techniques described
have the potential to improve the standard of care in their
respective indications.
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