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Trace Elements, Micronutrients, and Free Radicals (Hardcover, 1991 ed.)
Loot Price: R4,351
Discovery Miles 43 510
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Trace Elements, Micronutrients, and Free Radicals (Hardcover, 1991 ed.)
Series: Contemporary Issues in Biomedicine, Ethics, and Society
Expected to ship within 10 - 15 working days
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Itisonlyrecently thatthe naturaloccurrenceoffree radicalsin
biological tissue has become widely accepted, and that the suspi-
cion with which biologists previously viewed the free radicals of
radiationchemistryhas beenplacedin a broaderperspective. Now,
oxygen-derived free radicals are considered respectable biochemi-
cal intermediates, given always the caveat that unwanted tissue
damage may arise if these active species are produced in such
abundance that they overwhelm the natural antioxidant and free-
radical defense mechanisms, or if these systems have become
hypoeffective. Many factors, including several dietary manipula-
tions, can lead toelevatedproductionofsuperoxide and may result in
free radical overload, whereas a deficiency of those micronutri-
ents associated with the antioxidant defense mec.hanisms may re-
sult in substantially diminished antioxidant capacity. By now,
antioxidants have become a household word and al- most everyone is
aware of their imponance in protecting the body against attack by
active oxygen species. Indeed, it is a paradox of nature that
oxygen, which is so essential to sustain aerobic life, ul- timately
contributes to its destruction. Not surprisingly, recogni- tion
ofthis dilemma has generated a spate ofantioxidant strategies
intended to reduce the risk of tissue damage by rampant oxygen
radicals, some sadly based less on science than on speculation.
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