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Translational Regulation of Gene Expression 2 (Paperback, Softcover reprint of the original 1st ed. 1993)
Loot Price: R1,528
Discovery Miles 15 280
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Translational Regulation of Gene Expression 2 (Paperback, Softcover reprint of the original 1st ed. 1993)
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Total price: R1,548
Discovery Miles: 15 480
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This book, which results from the dramatic increase in interest in
the control mechanism employed in gene expression and the
importance of the regulated proteins, presents new information not
covered in Translational Regulation of Gene Expression, which was
published in 1987. It is not a revision of the earlier book but,
rather, an extension of that volume witl, special emphasis on mecha
nIsm. As the reader will discover, there is enormous diversity in
the systems employing genes for translational regulation in order
to regulate the appearance of the final product-the protein. Thus,
we find that important proteins such as protooncogenes, growth
factors, stress proteins, cytokines, lymphokines, iron storage and
iron-uptake proteins, and a panorama of prokaryotic proteins, as
well as eukaryotic viral proteins, are translationally regulated.
Since for some gene products the degree of control is greater by a
few orders of magnitude than their transcription, we can state that
for these genes, at least, the expression is translationall y
controlled. Translational regulation of gene expression in
eukaryotes has emerged in the last few years as a major research
field. The present book describes mechanisms of translational
regulation in bacteria, yeast, and eukaryotic viruses, as well as
in eukaryotic genes. In this book we try to provide in-depth
coverage by including important examples from each group rather
than systematically including all additional systems not described
in the previous volume.
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