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Kinetics of Drug Action (Paperback, Softcover reprint of the original 1st ed. 1977)
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Kinetics of Drug Action (Paperback, Softcover reprint of the original 1st ed. 1977)
Series: Handbook of Experimental Pharmacology, 47
Expected to ship within 10 - 15 working days
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Most drugs, toxins, hormones, and the like bring about their
biologic actions by reacting with specific receptors somewhere in
the body. Scientists working in all areas of biologic science have
shown increasing interest in the analysis of drug-receptor
interactions in the broadest sense. Studies of drugs (binding) to
receptors in situ and to isolated and partly purified receptors are
becoming common practice. The action of a drug in the body is,
however, a kinetic event not only with respect to transport of drug
molecules to the environment of the receptors, but also with
respect to the drug-receptor interaction itself. Kinetics of Drug
Action is an integrative approach to drug transport through the
body, membrane transport toward the receptors, and the kinetics of
drug receptor interaction. This volume is aimed at providing a
critical and penetrating study of the problems relevant to the
kinetics or drug action from drug dosage to the final response. It
is felt that the critical surveys presented in this volume will
contribute significantly to receptor study research in various
biologic fields and to a better understanding of drug action. I
would like to express my gratitude to our secretary Miss MARGOT
JANSSEN for the extensive typing of manuscripts and to our
laboratory assistant Miss COBY HURKMANS for her dedicated
assistance in the correcting some of the manuscripts and
preparating the index."
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