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Applied Molecular Genetics of Filamentous Fungi (Hardcover, 1992 ed.)
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Applied Molecular Genetics of Filamentous Fungi (Hardcover, 1992 ed.)
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The filamentous fungi are perhaps unique in the diversity of their
metabolic activities. This includes biosynthetic as well as
degradative activities, many is to provide an of which are of
industrial interest. The objective of this text up-to-date and
broad review which emphasizes the genetic and molecular biological
contribution in the field of fungal biotechnology. This text begins
with an overview of the tools and methodologies involved which, to
a large extent, have been developed in the model filamentous fungus
Aspergillus nidulans and subsequently have been extended to
commercially important fungi. This is followed by a chapter which
provides a compilation of genes isolated from commercial fungi and
their present status with respect to structure, function and
regulation. Chapters 3 and 4 highlight the degradative powers of
filamentous fungi. First, a discussion of what is known regarding
the molecular genetics of fungi and the genes and enzymes involved
in the beverage and food industries. This has an oriental flavour,
reflecting the tremendous importance of fungi in traditional
Chinese and Japanese food production. An account of lignocellulose
degradation by filamentous fungi follows, illustrating the
potential of fungi to utilize this substance as a renewable energy
source. The ability of fungi to produce high-value foreign proteins
is reviewed in chapters 5 and 6. Chymosin production, in
particular, represents a good example of high-level yields being
obtained, such as to warrant commercial production.
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