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Bioorganic Chemistry - Deoxysugars, Polyketides and Related Classes: Synthesis, Biosynthesis, Enzymes (Paperback, 1st ed. 1997. 2nd printing 2000)
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Bioorganic Chemistry - Deoxysugars, Polyketides and Related Classes: Synthesis, Biosynthesis, Enzymes (Paperback, 1st ed. 1997. 2nd printing 2000)
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Biosynthesis, chemical synthesis, combinatorial synthesis,
enzymatic synthesis, enzymes and genetics are subjects of
considerable interest. These themes are dealt with in three areas
of current bioorganic research. Deoxysugars and deoxy-
oligosaccharides are important structural moieties in bio- active
natural products. What is their contribution to the mode of action
and how can they be studied? Synthetic strategies, biosynthesis and
the genetics involved are presented. The second review article, on
non-template based multienzyme systems, addresses the question why
polyketides are the most diverse group of natural products.
Polyketide syntheses are compared with other non-template
multienzyme systems. The third review article deals with
angucycline antibiotics, the largest subgroup of polycyclic
aromatic polyketides.
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