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Drug Safety Evaluation - Methods and Protocols (Hardcover, 2nd ed. 2017)
Loot Price: R5,064
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Drug Safety Evaluation - Methods and Protocols (Hardcover, 2nd ed. 2017)
Series: Methods in Molecular Biology, 1641
Expected to ship within 12 - 17 working days
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This second edition provides up-to-date chapters and new chapters
focusing on the most recent advances in the field of drug safety
evaluation. Divided into seven parts, chapters detail specific
aspects related to the experimental design of preclinical studies
conducted to support the safety of pediatric and combination drugs,
necropsy and histopathology evaluation, mass spectrometry imaging,
genetic toxicology protocols including the Pig-a mutation assay,
safety pharmacology methods such as automatization of patch-clamp
procedures, target safety assessment for investigative toxicology,
screening assays for developmental toxicology, and methods to
characterize novel translational safety biomarkers like microRNAs.
Written in the highly successful Methods in Molecular Biology
series format, chapters include introductions to their respective
topics, lists of the necessary materials and reagents,
step-by-step, readily reproducible laboratory protocols, and tips
on troubleshooting to avoid known pitfalls. Authoritative and
practical, Drug Safety Evaluation: Methods and Protocols, Second
Edition aims to ensure successful results in the further study of
this vital field.
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