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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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Alternative Mechanisms of Multidrug Resistance in Cancer (Paperback, Softcover reprint of the original 1st ed. 1995)
Loot Price: R1,481
Discovery Miles 14 810
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Alternative Mechanisms of Multidrug Resistance in Cancer (Paperback, Softcover reprint of the original 1st ed. 1995)
Expected to ship within 10 - 15 working days
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Donate to Against Period Poverty
Total price: R1,501
Discovery Miles: 15 010
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Nullius in verba. . . Truth will be tested not by words. Horace
(Epistles) Few read introductions except for book reviewers, who
want to take a shortcut and avoid reading the book itself. However,
tradition requires that the preface make public why the book was
written at all (this is not supposed to include powerful reasons
such as augmenting the ego of the editor and authors). Frequently,
the inflationary tendency to publish in verbose length is in
conflict with market forces and interest. No doubt, multidrug
resistance is a "fashionable" topic, but there are many fashions
displayed on the cat-walk of scientific literature. One can
rationalize that the forces driving our concern with multi drug
resistance reflect the frustration of pharmaceutical companies and
oncologists alike: as soon as a new anticancer drug enters clinical
trials, cancer cells start eluding extinction with their elaborate
and successful mechanisms. Many grants have been awarded and spent,
only to confirm the futility of our efforts to defeat this cellular
Darwinism. Our medical and scientific training makes it hard, if
not impossible, to accept that the survival of a malignant cell,
alone or as part of a tissue, is part of the continuance of life.
Since exposure to noxious and lethal substances is unavoidable,
cells have been forced to develop a multitude of mechanisms to
prevent entry or accelerate exit of such materials from
intracellular space.
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