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Biology of Copper Complexes (Hardcover, 1987 ed.)
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Biology of Copper Complexes (Hardcover, 1987 ed.)
Series: Experimental Biology and Medicine, 16
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In 1928, it was discovered that copper was essential for normal
human metabolism. Ten years later, 1938, it was observed that
patients with rheumatoid arthritis had a higher than normal serum
copper concentration, which returned to normal wi th remission of
this disease. Thirteen years later, it was found that copper
complexes were effective in treating arthritic diseaseS. The first
report that copper complexes had antiinflammatory activity in an
animal model of in flammation appeared twenty-two years after the
discovery of essen tiality. In 1976, it was suggested that the
active forms of the anti arthritic drugs are their copper complexes
formed in vivo. This suggestion was confirmed and extended in the
interim with over 1000 recent publications, and many of these were
addressed in the proceed ings of our first symposium, published in
1982. The present symposium was organized to present new normal
physiological, nutritional, and biochemical aspects of essential
metal loelement metabolism as well as variations in metabolism
associated with disease states. In addition new data concerning
antimicrobial, antiinflammatory, antiulcer, anticancer,
anticarcinogenic, analgesic, and radioprotectant activities of
copper complexes were presented. These activities are consistent
with the notion that they represent the facilitation of normal
copper-dependent metabolic processes in dis ease states. The
presentations and interactive discussions that fol lowed are
contained in these proceedings. John R. J. Sorenson Dedication
These proceedings are dedicated to those who made this truly
memorable scientific and social Arkansas experience possible."
General
Imprint: |
HumanaPress
|
Country of origin: |
United States |
Series: |
Experimental Biology and Medicine, 16 |
Release date: |
October 1987 |
First published: |
1987 |
Authors: |
John R.J. Sorenson
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Dimensions: |
229 x 152 x 33mm (L x W x T) |
Format: |
Hardcover
|
Pages: |
598 |
Edition: |
1987 ed. |
ISBN-13: |
978-0-89603-123-4 |
Categories: |
Books >
Medicine >
Clinical & internal medicine >
Rheumatology
Promotions
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LSN: |
0-89603-123-3 |
Barcode: |
9780896031234 |
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