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Books > Medicine > Clinical & internal medicine > Medical diagnosis
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Diagnostic Virology Protocols (Hardcover, 1998 ed.)
Loot Price: R4,580
Discovery Miles 45 800
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Diagnostic Virology Protocols (Hardcover, 1998 ed.)
Series: Methods in Molecular Medicine, 12
Expected to ship within 10 - 15 working days
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The accurate and reliable diagnosis of transmissible diseases is
the most powerful weapon available to ensure their control, and in
some cases eradication. The detection of parasites in clinical
cases, companion and farm animals, and in the environment is
relatively easy since many of them are visible to the naked eye,
and those that are not are readily detected by light microscopy.
Fungal infections can similarly be determined. Bacteria are
somewhat harder to detect. Although their presence can frequently
be detected by light microscopy, differential diagnosis, beyond
their gross morphology, is almost always impossible. However, most
bacterial pathogens can be cultured in the laboratory and can be
accurately identified by combinations of a series of simple tests
such as morphology, staining, antibiotic sensitivity, biochemical
analyses, nutrient dependence, and phage sensitivity. Viruses,
however, have proved much more difficult; their size and absolute
dependence of the host cell for propagation have rendered useless
the methods traditionally used for other microorganisms. Until the
development of tissue culture in the middle of this century,
diagnosis was entirely dependent on the skill and experience of the
clinician. But this was an unreliable process since many of the
common virus infections exhibit similar clinical symptoms, such as
coryza, exanthema, vomiting, diarrhea, neuralgia, and lethargy.
Indeed many viral infections display clinical signs that are
indistinguishable from bacterial or parasitic infections.
General
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