Lung Function Testing in the 21st Century: Methodologies and Tools Bridging Engineering to Clinical Practice covers the complete aspects of lung function testing, ranging from standardized to newly introduced (IOS, FOT) methods. It provides an updated overview of advances in respiratory engineering, along with advice on which lung function tests are appropriate for which purpose. The author discusses non-standardized lung function testing, methods, clinical tests, diagnosis and future perspectives. Lung function measurement devices and protocols are also covered. This book covers multidisciplinary domains, bringing new technology ideas from mathematics, physics, biology and engineering into the field of respiratory engineering. Users will find a single resource that brings together all of the disparate information on lung function testing technology currently contained in many journal articles.

Advances in Clinical Chemistry, Volume 87, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, and is the benchmark for novel analytical approaches in the clinical laboratory.

Whereas most books about neurologic examinations are disease and anatomy oriented, The Neurologic Examination: Scientific Basis for Clinical Diagnosis focuses on a pathophysiological approach to the nervous system. The authors emphasize that the scientific interpretation of symptoms obtained from carefully taking the patient's history and noting signs found during physical examination are essential in the diagnosis of neurologic diseases, even if laboratory testing, such as electrophysiology and neuroimaging, are being more widely used. This book aims to provide a bridge from the basic sciences such as anatomy, physiology, pharmacology, and molecular biology to the neurologic symptoms. Neurologic examinations provide the foundation for the diagnosis, and only after a thorough and expertly executed examination can one begin to incorporate laboratory testing and treatment. The Neurologic Examination: Scientific Basis for Clinical Diagnosis, based on the widely successful Japanese book Diagnosis of Neurological Diseases (Igakushoin, Japan, second edition 2013) by Dr. Shibasaki, hopes to revitalize the use of neurologic examinations before jumping straight into laboratory testing. Doing so can help cut down on time, patient and physician anxiety, and unnecessary testing expenses. This book is a must-read for all practicing neurologists, residents, and medical students. Key Features Include * The chapters are arranged in order of the actual steps in a neurologic examination; * Highly illustrated with figures and tables indicative of the neurologic signs and symptoms that may appear during the given step; and * 99 discussion boxes are inserted throughout to provide a more in-depth look at particular topics without interrupting the reading flow of the text.

This issue of MRI Clinics of North America focuses on Functional MRI in Oncology. Articles will include: Functional MRI techniques in oncology in the era of personalized medicine, MRI biomarkers and surrogate endpoints in oncology clinical trials, Therapy monitoring with functional MRI, Multiparametric MRI in the assessment of brain tumors, Multiparametric MRI of breast cancer, Functional MRI in chest malignancies, Multiparametric MRI in abdominal malignancies, Assessment of musculoskeletal malignancies with functional MRI, Evaluation of head and neck tumors with functional MRI, Role of multiparametric MRI in malignancies of the urogenital tract, Diffusion-weighted imaging in oncology, Functional MRI in gynecologic cancer, Assessment of angiogenesis with MRI: DCE-MRI and beyond, Imaging of tumor metabolism: MR spectroscopy, and more!

This issue of PET Clinics focuses on Special Techniques and Technical Advances in PET/CT Imaging. Articles will include: PET/CT Guided FNAC/Biopsy; Dual Time Point Imaging; Overview of Conventional imaging based intervention in clinical practice; Special Techniques in PET/CT in evaluating genito-urinary malignances; Special techniques in PET/CT imaging for evaluation of head and neck cancer; PET/CT enteroclysis; Contrast media in PET/CT imaging; PET/CT guided RFA; Non-attenuated corrected PET/CT imaging and applications; and more!

Living with a skin condition can have a significant impact on way of life and emotional well-being. Psychodermatology is the practice of treating a skin condition using psychological techniques. This book is a concise guide to psychodermatology for dermatologists. Beginning with an overview providing clinicians with an understanding of the psychological issues associated with dermatological issues. The following chapters discuss different types of skin disorder and treatment strategies including meditation, psychotherapy, hypnotherapy, and psychopharmacology. The text differentiates clearly between primary and secondary psychological disorders, and psychophysiological conditions. A complete section is dedicated to assessment tools and questionnaires. Each chapter begins with a 'key points' section and includes case vignettes to assist learning. Key points Concise guide to management of psychological impact of skin disorders Covers numerous skin conditions and treatment methods Complete section provides clinicians with assessment tools and questionnaires Each chapter includes 'key points' and case vignettes

Here is the Fourth Edition of the classic text Electrodiagnosis in Diseases of Nerve and Muscle. With each subsequent edition, Dr. Kimura has built upon his extensive experience teaching electromyography (EMG) around the world and has transferred his knowledge to the book. It is intended for clinicians who perform electrodiagnostic procedures as an extension of their clinical examination, and will be of value to neurologists and physiatrists who are interested in neuromuscular disorders and noninvasive electrodiagnostic methods, particularly those practicing electromyography (EMG). The book provides a comprehensive review of most peripheral nerve and muscle diseases, including specific techniques and locations for performing each test. While the book has been thoroughly updated to reflect the growth that has been made in the field since 2001, a DVD has also been added to the book, allowing the readers to watch and listen to various types of normal and abnormal EMG activities. The book is designed for those interested in a broad review of electrodiagnostic medicine, especially to those dealing with patients with neuromuscular disorders, who may benefit from a referral for electromyography and nerve conduction studies as part of the clinical practice. It will appeal to those wanting a current update on the subject and those interested in state of the art information and observation of electrophysiologic techniques.

Neurodevelopmental Disorders: DSM-5 Selections is crafted around a specific disorder cited in DSM-5. This selection provides a comprehensive overview of the process of diagnosing neurodevelopmental disorders while serving as a reference guide to assist in the diagnosis of individual patients. The disorder-specific resource is an invaluable addition to the DSM-5 collection and an important contribution to the mental health profession. This book contains the critical disorder-specific content from these four titles: * Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) * DSM-5 Clinical Cases* DSM-5 Self-Exam Questions* DSM-5 Guidebook

Antimicrobial Dressings: The Wound Care Applications explores the literature surrounding the catalytic behavior of proteolytic enzymes immobilized together with nanoparticles. As numerous applications using proteolytic enzymes for debridement, silver as antibiotic and nanoparticles for enzyme immobilization were developed in the last years, this book explores interdisciplinary information combining nanotechnology, biotechnology and medicine and how it's still in early stages. The book adopts a holistic approach in a lifecycle context to evaluate their final feasibility, including industrial exploitability without disregard of the potential risks of enzymes and nanomaterials to human health and the environment.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Written by a single author and authority in the field, "The Clinical Marker hCG" addresses several sensitive areas of clinical tests for the marker hCG: interpretation of results, different reference standards, application to pregnancy testing, early detection of hCG, differential of diagnosis of ectopic pregnancy, diagnostic potential in conjunction with ultrasound, use as a tumor marker, immunocytochemical applications, low-level hCG analysis, discordant results, and significance of subunits and their measurement. The evolution of hCG tests is thoroughly reviewed, with a clear description of the new generation immunoenzymetric tests and their advantages.

Recent Trends in Computer-aided Diagnostic Systems for Skin Diseases: Theory, Implementation, and Analysis provides comprehensive coverage on the development of computer-aided diagnostic (CAD) systems employing image processing and machine learning tools for improved, uniform evaluation and diagnosis (avoiding subjective judgment) of skin disorders. The methods and tools are described in a general way so that these tools can be applied not only for skin diseases but also for a wide range of analogous problems in the domain of biomedical systems. Moreover, quantification of clinically relevant information that can associate the findings of physicians/experts is the most challenging task of any CAD system. This book gives all the details in a step-by-step form for different modules so that the readers can develop each of the modules like preprocessing, feature extraction/learning, disease classification, as well as an entire expert diagnosis system themselves for their own applications.

Recent advancements in the technology of medical imaging, such as CT and MRI scanners, are making it possible to create more detailed 3D and 4D images. These powerful images require vast amounts of digital data to help with the diagnosis of the patient. Artificial intelligence (AI) must play a vital role in supporting with the analysis of this medical imaging data, but it will only be viable as long as healthcare professionals and AI interact to embrace deep thinking platforms such as automation in the identification of diseases in patients. AI Innovation in Medical Imaging Diagnostics is an essential reference source that examines AI applications in medical imaging that can transform hospitals to become more efficient in the management of patient treatment plans through the production of faster imaging and the reduction of radiation dosages through the PET and SPECT imaging modalities. The book also explores how data clusters from these images can be translated into small data packages that can be accessed by healthcare departments to give a real-time insight into patient care and required interventions. Featuring research on topics such as assistive healthcare, cancer detection, and machine learning, this book is ideally designed for healthcare administrators, radiologists, data analysts, computer science professionals, medical imaging specialists, diagnosticians, medical professionals, researchers, and students.

Material-Microbes Interactions: Environmental Biotechnological Perspective brings great insights into microbes-material interactions, biofilm formation, and emerging bioprocess within the field of applied biotechnology. The book systematically summarizes the fundamental principles, the state-of-the-art in microbes-material interaction, and its application in bioprocess and environmental technology development. Understanding the fundamental processes of biofilm formation, the role of material to exchange the energy with microbes, biofilm matrix, and optimization of the biofilm formation process is useful to everyone involved with bioprocess development. This book will be of significant interest to environmental technology developers, researchers, university professors, policymakers, graduate and postgraduate students and other stakeholders. Interestingly, academic institutions, wastewater treatment plants, and research centers have upscaled biofilm-based environmental technologies, such as moving bed bioreactors, microalgae, tricking bed reactors, biofilters, and bioelectrochemical process as promising environmental technologies.

There is a significant deficiency among contemporary medicine practices reflected by experts making medical decisions for a large proportion of the population for which no or minimal data exists. Fortunately, our capacity to procure and apply such information is rapidly rising. As medicine becomes more individualized, the implementation of health IT and data interoperability become essential components to delivering quality healthcare. Quality Assurance in the Era of Individualized Medicine is a collection of innovative research on the methods and utilization of digital readouts to fashion an individualized therapy instead of a mass-population-directed strategy. While highlighting topics including assistive technologies, patient management, and clinical practices, this book is ideally designed for health professionals, doctors, nurses, hospital management, medical administrators, IT specialists, data scientists, researchers, academicians, and students.

Medical and information communication technology professionals are working to develop robust classification techniques, especially in healthcare data/image analysis, to ensure quick diagnoses and treatments to patients. Without fast and immediate access to healthcare databases and information, medical professionals' success rates and treatment options become limited and fall to disastrous levels. Advanced Classification Techniques for Healthcare Analysis provides emerging insight into classification techniques in delivering quality, accurate, and affordable healthcare, while also discussing the impact health data has on medical treatments. Featuring coverage on a broad range of topics such as early diagnosis, brain-computer interface, metaheuristic algorithms, clustering techniques, learning schemes, and mobile telemedicine, this book is ideal for medical professionals, healthcare administrators, engineers, researchers, academicians, and technology developers seeking current research on furthering information and communication technology that improves patient care.

Design of Nanostructures for Theranostics Applications focuses on the theranostics applications of nanostructures. In particular, multifunctional nanoparticles for diagnostics and treatment of different diseases, including those relating to the blood-brain barrier, are discussed in detail. Chapters explore different type of nanostructures, covering design, fabrication, functionalization and optimization, helping readers obtain the desired properties. Written by a diverse range of international academics, this book is a valuable reference resource for those working in both nanoscience and the pharmaceutical industry.

Hyperpolarized and Inert Gas MRI: Theory and Applications in Research and Medicine is the first comprehensive volume published on HP gas MRI. Since the 1990's, when HP gas MRI was invented by Dr. Albert and his colleagues, the HP gas MRI field has grown dramatically. The technique has proven to be a useful tool for diagnosis, disease staging, and therapy evaluation for obstructive lung diseases, including asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis. HP gas MRI has also been developed for functional imaging of the brain and is presently being developed for molecular imaging, including molecules associated with lung cancer, breast cancer, and Alzheimer's disease. Taking into account the ongoing growth of this field and the potential for future clinical applications, the book pulls together the most relevant and cutting-edge research available in HP gas MRI into one resource.