This book presents an authoritative overview of the emerging field of person-centered psychiatry. This perspective, articulating science and humanism, arose within the World Psychiatric Association and aims to shift the focus of psychiatry from organ and disease to the whole person within their individual context. It is part of a broader person-centered perspective in medicine that is being advanced by the International College of Person-Centered Medicine through the annual Geneva Conferences held since 2008 in collaboration with the World Medical Association, the World Health Organization, the International Council of Nurses, the International Federation of Social Workers, and the International Alliance of Patients' Organizations, among 30 other international health institutions. In this book, experts in the field cover all aspects of person-centered psychiatry, the conceptual keystones of which include ethical commitment; a holistic approach; a relationship focus; cultural sensitivity; individualized care; establishment of common ground among clinicians, patients, and families for joint diagnostic understanding and shared clinical decision-making; people-centered organization of services; and person-centered health education and research.

Originally published in 1951, this title looks at the study of the hand in relation to psychological diagnosis. This was at the time a new branch of psychology and the author is keen to point out it must not be viewed as perfect or indeed complete. Practical experience and a deeper understanding of psycho-motor phenomena had altered some of the author's theoretical views since the earlier titles. This book builds on and extends her previous research, including new research studies particularly on children who were at the time termed 'mentally defective'. It was designed to contribute some new diagnostic possibilities to psychology and psychiatry. Today we can enjoy it as part of psychology's history.

This book provides a current view of the research and commercial landscape of diagnostics devices, particularly those that utilize microscale technologies, intended for both patient and laboratory use. Common diagnostic devices that are based on microfluidic principles include glucose sensors for diabetic patients and over-the-counter pregnancy tests. Other diagnostic devices are being developed to quickly test a patient for bacterial and viral infections, and other diseases. The chapters, written by experts from around the world, discuss how to fabricate, apply, and market microfluidic diagnostic chips - for lab and at-home use. Most importantly, the book also contains a discussion of topics relevant to the private sector, including patient-focused, market-oriented development of diagnostics devices. Chapter 9 of this book is freely available as a downloadable Open Access PDF under a CC-BY 3.0 license. https://s3-us-west-2.amazonaws.com/tandfbis/rt-files/docs/Open+Access+Chapters/9781498772938_oachapter9.pdf

Get Ahead Medicine: OSCEs and Data Interpretation, the latest addition to the essential Get ahead revision series, provides practical and invaluable revision for all medical students preparing for these challenging examinations. A volume in the bestselling and highly praised Get ahead series Detailed scenarios covering the entire medical syllabus ensure thorough preparation for these examinations Each scenario contains a full mark scheme and accompanying detailed explanations allowing for a full understanding of revision needs Also includes abnormal findings, ensuring candidates are fully prepared beyond standard revision Written by a knowledgable author team with extensive experience in the examination, Get ahead Medicine: OSCEs and Data Interpretation, along with its companion volume on surgery and associated specialties, is the essential revision guide for not only passing but succeeding to exceptional standards within undergraduate clinical examinations.

"Kroll-Smith and Floyd have, with both clarity and sensitivity, provided considerable insight into an important arena of contemporary experience."
--"American Journal of Sociology"

"Elegantly written. . . . the book is built around the narratives of multiple chemical sensitivity (MCS) sufferers themselves. . . . Due to its relevant subject matter, its interdisciplinary approach, its readability, and its interesting theoretical arguments, "Bodies in Protest" should be appealing to a wide audience."
--"Organization and Environment"

"This engagingly written and thought-provoking book provides one of the first sustained sociological analyses of a baffling, controversial, and spectacular medical condition."
--"Social Forces"

Gulf War Syndrome: Is It a Real Disease? asks a recent headline in the "New York Times," This question--are certain diseases real?--lies at the heart of a simmering controversy in the United States, a debate that has raged, in different contexts, for centuries. In the early nineteenth century, the air of European cities, polluted by open sewers and industrial waste, was generally thought to be the source of infection and disease. Thus the term miasma--literally deathlike air--came into popular use, only to be later dismissed as medically unsound by Louis Pasteur.

While controversy has long swirled in the United States around such illnesses as chronic fatigue syndrome and Epstein-Barr virus, no disorder has been more aggressively contested than environmental illness, a disease whose symptoms are distinguished by an extreme, debilitating reaction to a seemingly ordinary environment. The environmentally ill range from those who have adverse reactionsto strong perfumes or colognes to others who are so sensitive to chemicals of any kind that they must retreat entirely from the modern world.

"Bodies in Protest" does not seek to answer the question of whether or not chemical sensitivity is physiological or psychological, rather, it reveals how ordinary people borrow the expert language of medicine to construct lay accounts of their misery. The environmentally ill are not only explaining their bodies to themselves, however, they are also influencing public policies and laws to accommodate the existence of these mysterious illnesses. They have created literally a new body that professional medicine refuses to acknowledge and one that is becoming a popular model for rethinking conventional boundaries between the safe and the dangerous.

Having interviewed dozens of the environmentally ill, the authors here recount how these people come to acknowledge and define their disease, and themselves, in a suddenly unlivable world that often stigmatizes them as psychologically unstable. "Bodies in Protest" is the dramatic story of human bodies that no longer behave in a manner modern medicine can predict and control.

History taking and examination skills are vitally important in everyday practice. They are examined at all levels of the undergraduate curriculum and are constantly monitored at a postgraduate level. To become proficient in history taking, key questions should be asked to quickly understand the exact nature of the illness. This invaluable guide specifies the questions required for a focused history and details the key components of the ideal examination, resulting in the development of clinical skills that are timely, comprehensive, relevant and succinct. Clearly laid out and easy-to-read, The Practical Pocket Guide to History Taking and Clinical Examination is highly recommended for medical students and junior doctors wanting a practical, quick reference to aid confidence and develop excellent clinical consultation skills. It is also ideal as an aide-memoire for exam preparation.

This text clearly presents a multitude of variables that potentially affect the results of neuropsychological tests. THe chapter authors, all noted experts in their respective fields, begin with a general discussion of neuropsychological constructs known to impact performance on neuropsychological tests, including demographics, personality, and sociocultural factors. They then present an empirical approach to assessment. They focus on the disorders under discussion (not solely the tests that might be used in diagnosis) and reflect the contributions the field has made to detecting differences in disorders that have neurological underpinnings.

The disorders reviewed include dementia, HIV-related syndromes, adult seizure disorders, toxic exposure, mild to severe brain injury, and chronic fatigue syndrome.

The "Diagnostic and Statistical Manual of Mental Disorders," more commonly known as the DSM, is published by the American Psychiatric Association, listing and describing all mental disorders. The publication of DSM-5 in 2013 brought many changes. "Diagnosing the Diagnostic and Statistical Manual of Mental Disorders 5" is written for all those who wonder whether the DSM-5 now classifies the right people in the right way. It is aimed at patients, mental health professionals, and academics with an interest in mental health. Issues addressed include: What are the main changes that have been made to the classification? How is the DSM affected by financial links with the pharmaceutical industry? To what extent were patients involved in revising the classification? How are diagnoses added to the DSM? Does medicalization threaten the idea that anyone is normal? What happens when changes to diagnostic criteria mean that people lose their diagnoses? How important will the DSM be in the future?

This encyclopedia examines more than 125 of the most important and commonly performed medical tests, providing readers with information about how and why they are performed and how each test contributes to monitoring health and diagnosing and treating medical conditions. Whether it's to proactively monitor health, diagnose a condition, or assess how well a particular treatment is working, we all undergo a variety of medical tests throughout our lives. While these tests provide valuable information for doctors and patients, they can sometimes carry significant risks, provide ambiguous or incorrect results, or raise more questions than they answer. Contrary to what some may think, medical testing isn't a simple "yes or no" science carried out by computers in a lab—it is a dynamic process that relies heavily on human detective work and interpretation. Medical Tests in Context: Innovations and Insights highlights more than 125 tests performed across a wide range of medical specialties. Each entry in this encyclopedia follows a standardized format that provides readers with information about how, when, and why the test is conducted; the preparation and risks; how results are determined and where errors might occur; and its history. A collection of case studies offers real-world examples of the successes—and shortcomings—of medical testing.

1: General Aspects of Laryngeal Cancer.- 1. Introduction.- 1.1. Incidence.- 1.2. Predisposing factors.- 2. TNM staging.- 2.1. Introduction.- 2.2. Clinical classification.- 3. Diagnostic aspects.- 3.1. History.- 3.2. External examination.- 3.3. Laryngoscopy.- 4. Therapeutic options.- 4.1. Radiotherapeutic options.- 4.1.1. Technique.- 4.1.2. Prognostic factors of irradiation treatment.- 4.1.3. Complications due to radiation therapy.- 4.2. Surgical options.- 4.2.1. Laser therapy and microsurgical stripping.- 4.2.2. Laryngofissure and cordectomy.- 4.2.3. Vertical partial laryngectomy.- 4.2.4. Antero-frontal laryngectomy for excision of the anterior commissure.- 4.2.5. Supraglottic laryngectomy.- 4.2.6. (Wide-field) total laryngectomy.- 4.3. Chemotherapeutic options.- 5. Therapeutic management.- Tl- and T2-glottic carcinomas.- T1- and T2-subglottic carcinomas.- T2- and T2-supraglottic carcinomas.- T3- and T4-laryngeal cancer.- Nodal metastasis.- References.- 2: The Patterns of Growth And Spread of Laryngeal Cancer.- 1. Introduction.- 2. Spread of cancer in various regions.- 2.1. Cancer of the supraglottic region.- 2.2. Cancer of the glottic region.- 2.3. Cancer of the subglottic region.- 3. Cartilage invasion.- 4. Lymphatic spread.- 5. Vascular and perineural invasion.- References.- 3: The Radiological Examination of the Larynx.- 1. Introduction.- 2. Phonation manoeuvers.- 3. Frontal tomography.- 4. Contrast laryngography.- 5. Computed tomography.- 6. CT versus conventional radiological techniques.- 6.1. CT versus conventional tomography.- 6.2. CT versus contrast laryngography.- References.- 4: General Aspects of MR Imaging.- 1. Introduction.- 2. Technical principles.- 2.1. Properties of atomic nuclei.- 2.2. Resonance.- 2.3. Behaviour of a sample of nuclei.- 2.4. Proton density, tissue characteristics.- 2.5. Spin echo technique.- 3. The equipment.- 3.1. Magnet.- 3.2. Gradient system.- 3.3. Coils.- 3.4. Computer.- 4. Disadvantages of MR imaging.- 4.1. Claustrophobia.- 4.2. Contra-indications.- References.- 5: MR Imaging Techniques of the Larynx.- 1. Surface coils.- 1.1. Coil selection.- 2. Parameters.- 2.1. Pulse sequences.- 2.2. Slice thickness.- 2.3. Slice direction.- 2.4. Matrix size.- 2.5. Number of signal measurements.- 3. Artifacts.- 3.1. Motion artifacts.- 3.2. System artifacts.- 3.3. Chemical shift artifacts.- 3.4. Artifacts due to ferromagnetic implants.- 4. Performance of the laryngeal examination.- References.- 6: MR Imaging of the Normal Larynx.- 1. Introduction.- 2. MR imaging of laryngeal structures.- 2.1. Laryngeal skeleton.- 2.2. Laryngeal compartments.- 3. Landmarks.- 3.1. Hyoid bone.- 3.2. Aryepiglottic fold.- 3.3. False vocal cords.- 3.4. True vocal cords.- 3.5. Subglottic level.- References.- 7: MR Imaging of Laryngeal Cancer.- Abstract.- 1. Introduction.- 2. Materials and methods.- 3. Case reports.- Case 1.- Case 2.- Case 3.- Case 4.- Case 5.- Case 6.- Case 7.- 4. Discussion.- 5. Conclusions.- References.- 8: MR imaging of Normal and Cancerous Laryngeal Cartilages. Histopathological Correlation.- Abstract.- 1. Introduction.- 2. Materials and methods.- 3. Results.- 3.1. Epiglottic cartilage.- 3.2. Thyroid cartilage.- 3.3. Cricoid cartilage.- 3.4. Arytenoid cartilage.- 4. Discussion.- 5. Conclusions.- References.- 9: Dagnosis of Laryngeal Cartilage Invasion by Cancer. Comparison of CT and MR Imaging.- Abstract.- 1. Introduction.- 2. Materials and methods.- 2.1. Imaging techniques.- 2.2. Image interpretation.- 2.3. Pathological findings.- 3. Results.- 3.1. Epiglottic cartilage.- 3.2. Thyroid cartilage.- 3.3. Arytenoid cartilage.- 3.4. Cricoid cartilage.- 3.5. Group of patients for which no pathologic correlation was available.- 3.6. Movement artifacts.- 4. Discussion.- 4.1. Elastic cartilage: epiglottic cartilage.- 4.2. Hyaline cartilage: thyroid, cricoid and arytenoid cartilages.- 5. Summary.- References.- 10: MR Findings of Cartilage Invasion by Laryngeal Cancer. Value in Predicting Outcome of Radiation Therap...

Use this pocket-sized guide to make nursing diagnoses and formulate care plans! Ackley and Ladwig's Guide to Nursing Diagnosis, 7th Edition provides quick access to more than 1300 specific client symptoms and a logical, step-by-step guide to care planning. A condensed version of Ackley and Ladwig's Nursing Diagnosis Handbook, this guide is updated with the 2021-2023 NANDA-I approved nursing diagnoses. Care plans are suggested for each diagnosis, including interventions, desired outcomes, and patient teaching. From nursing educators Marina Reyna Martinez-Kratz and Mary Beth Flynn Makic, this reference is ideal for use in in class, clinicals, or at the bedside! Section I: Guide to Nursing Diagnoses includes an alphabetical listing of client symptoms, client problems, medical diagnoses, psychosocial diagnoses, and clinical states, along with suggested 2021-2023 NANDA-I (R) approved nursing diagnoses, allowing you to evaluate and select an appropriate diagnosis for the client. Section II: Guide to Planning Care includes care plans for all 2021-2023 NANDA-I approved nursing diagnoses, including evidence-based, independent, collaborative, geriatric, pediatric, home care, and culturally competent interventions, as well as client/family teaching and discharge planning. Pocket-size portability makes this book easy to carry and use in in class, clinicals, or at the bedside. Alphabetical thumb tabs provide quick access to specific symptoms and nursing diagnoses. Index of NANDA-I Diagnoses is included on the inside front and back covers. NEW and UNIQUE! 2021-2023 NANDA-I (R) approved nursing diagnoses are updated with new and revised diagnoses. NEW! Updated nursing diagnoses include class and domain information consistent with the current NANDA-I.

Volatile organic compounds (VOCs) in exhaled breath, sweat or urine carry much information on the state of human health. The role of VOCs in clinical diagnosis and therapeutic monitoring is expected to become increasingly significant due to recent advances in the field. "Volatile Biomarkers: Non-Invasive Diagnosis in Physiology and Medicine" includes the latest discoveries and applications for VOCs from the world's foremost scientists and clinicians working in this emerging analytic area.

- Appeals to a multidisciplinary audience, including scientists, researchers, and clinicians with an interest in breath analysis

- Features the latest scientific research and technical breakthroughs in the diagnostic and therapeutic aspects of volatile organic compounds

- Includes case presentations documenting applications in multiple areas of human health and safety

As healthcare costs rise, so too do the costs of assessment instruments, critical tools for mental health professionals. While some traditional assessment instruments have become prohibitively expensive, as with many other fields, the Internet offers a host of more affordable and equitable alternative assessment tools at little or no cost. The pitfall of this alternative, thus far, has been the lack of vetting and quality assessment. Assessing Common Mental Health and Addiction Issues With Free-Access Instruments fills this gap by providing the first analysis and assessment of these tools, provided by some of the leading names in mental health assessment instruments. This resource identifies the most efficient free access instruments and provides summary information about administration, scoring, interpretation, psychometric integrity, and strengths and weaknesses. The book is organized around the most common broad range issues encountered by helping professionals, and whenever possible, a link to the instrument itself is provided. This is an essential text for all mental health professionals looking to expand the scope and range of their assessment instruments.

As healthcare costs rise, so too do the costs of assessment instruments, critical tools for mental health professionals. While some traditional assessment instruments have become prohibitively expensive, as with many other fields, the Internet offers a host of more affordable and equitable alternative assessment tools at little or no cost. The pitfall of this alternative, thus far, has been the lack of vetting and quality assessment. "Assessing Common Mental Health and Addiction Issues With Free-Access Instruments" fills this gap by providing the first analysis and assessment of these tools, provided by some of the leading names in mental health assessment instruments. This resource identifies the most efficient free access instruments and provides summary information about administration, scoring, interpretation, psychometric integrity, and strengths and weaknesses. The book is organized around the most common broad range issues encountered by helping professionals, and whenever possible, a link to the instrument itself is provided. This is an essential text for all mental health professionals looking to expand the scope and range of their assessment instruments.

The first pocket-size resource to guide PA students through their emergency medicine rotation.Prepare for and thrive during your clinical rotations with the quick-access pocket guide series, The Physician Assistant Student's Guide to the Clinical Year. The Emergency Medicine edition of this 7-volume series delineates the exact duties required in this specialty. Written by experienced PA educators, this guide details the clinical approach to common presentations such as chest pain, altered mental status, and headache. It also provides a systems-based approach to more than 40 of the most frequently encountered disease entities you will see in this rotation, including traumatic injury, cerebrovascular accident, and acute coronary syndrome. Distinguished by brief, bulleted content with handy tables and figures, the reference offers all pertinent laboratory and imaging studies needed to confirm a diagnosis, with medication and management guidelines. This guide also describes the most common procedures you will learn during the emergency medicine rotation, including incision and drainage, wound repair, and foreign body removal. Also included is a special chapter on non-medical situations you'll find in the emergency department, such as drug-seeking behavior, violent or incarcerated patients, and malingering and factitious disorders. Key Features: Provides a pocket-size overview of the PA emergency medicine rotation Describes common clinical presentations, disease entities, and procedures Offers clinical pearls throughout Reflects the 2019 NCCPA PANCE blueprint Includes three bonus digital chapters! Guided case studies to reinforce clinical reasoning, 25 rotation exam-style questions with remediating rationales, and additional resources to enhance your emergency department experience Other books in this series: The Physician Assistant Student's Guide to the Clinical Year: Family Medicine; Internal Medicine; Surgery; OB-GYN; Pediatrics; Behavioral Health

Accurately identify complex geometrical distortions of cardiac anatomy and make more informed decisions regarding diagnosis and treatment with Atlas of 3D Echocardiography. This new cardiology reference presents the authoritative, case-based, expert guidance you need to enhance your utilization and interpretation of this cutting-edge, dimensional diagnostic tool. Master the application of techniques to specific clinical situations with detailed case studies and discussions of challenging issues. See imaging findings as they appear in practice and discern subtle nuances with the aid of high-quality still images plus online videos. Reference the information you need quickly thanks to easy-to-follow, templated chapters, with an abundance of images and figures that facilitate visual learning. Take it with you anywhere! Access the full text, downloadable image library, videos, and more at www.expertconsult.com. Sharpen your interpretive and diagnostic skills in 3-D echo!

The aim of Hematologic Malignancies: Methods and Techniques is to review those methods most useful for the diagnosis and subsequent mana- ment of hematologic malignancies. The scope of coverage is intentionally broad, ranging from routine procedures to highly sophisticated methods not currently offered by most clinical laboratories. The latter methods were selected especially to bring into focus recent advances in molecular biology that, since they provide us with strong tools for assessing the outcome of upcoming therapeutic modalities intent on disease eradication, are expected to impact the future diagnosis and management of these diseases. Thus, the c- mon thread among all chapters is clinical relevance, whether sanctioned by past experience or by the expectation that seemingly esoteric research techniques of today will prove clinically valuable in the future. Hematologic Malignancies: Methods and Techniques is primarily a compilation of methods presented in sufficient detail-by authors with extensive expertise in their field-to serve not only as a reference for seasoned research and clinical laboratory pers- nel, but also as a guide for the less experienced. Moreover, the contributing authors also discuss the pathophysiologic bases and the diagnostic usefulness that underscore each method's clinical relevance. Thus, this volume should be also valuable to clinicians-especially hematologists, oncologists, and path- ogists-often bewildered by an ever increasing flow of new scientific inf- mation, the practical application of which is often either not clearly disclosed or difficult to discern.

This new volume in the Toolkit series is designed for clinicians and junior researchers who need to interpret the evidence for the effectiveness of the many diagnostic tests now available. Exceptionally user-friendly, this pocket-sized textbook realizes readers are not experts in diagnostic test interpretation. The authors cover a variety of issues, from how to design diagnostic test studies to understanding the results of diagnostic tests and interpreting the findings for clinical practice and health care policy.

Combining the fundamental coverage of a traditional nursing assessment text with a modern, student-friendly presentation and an enhanced emphasis on clinical judgment, Nursing Health Assessment: A Clinical Judgment Approach, 4th Edition, helps students easily develop the understanding, critical thinking, and decision-making skills to excel in any clinical setting. A consistent, two-column format presents normal and abnormal findings and guides students progressively through realistic clinical case scenarios, instilling the nursing knowledge to observe and assess situations, prioritize patient concerns, and generate the best possible solutions. Case-based Next Generation NCLEX (R) (NGN) style questions throughout the text (and answers with rationales in an appendix) align with the NCSBN Clinical Judgment Model (NCJMM) to prepare students for success on the Next Generation NCLEX (R) and to help them confidently deliver safe patient care in any clinical setting. New and Updated Features for the 4th Edition NEW! 180 case-based Next Generation NCLEX (R) (NGN) style questions (and answers with rationales) boost students' exam readiness and test-taking confidence. NEW! NCSBN Clinical Judgment Measurement Model (NCJMM) cues, hypotheses, and evaluation components incorporated into case studies throughout the text strengthen students' critical thinking and decision-making capabilities. UPDATED! New and revised content familiarizes students with social determinants of health, incorporates unbiased language, and reflects current infection and source control measures. UPDATED! Diagnoses incorporate International Classification for Nursing Practice [INCP] language to clarify challenging terminology.

The first pocket-size resource to guide PA students through their OB/GYN rotation.Prepare for and thrive during your clinical rotations with the quick-access pocket guide series, The Physician Assistant Student's Guide to the Clinical Year. The OB/GYN edition of this 7-volume series delineates the exact duties required in obstetrics and gynecology. Written by an experienced PA educator, this guide details the clinical approach to common obstetric and gynecologic presentations such as pelvic pain, abnormal uterine bleeding, and an overview of the initial prenatal visit. It also provides treatment and management details for more than 30 of the most frequently encountered disease entities you will see in this rotation, including cervical dysplasia, dysmenorrhea, and ectopic pregnancy. Distinguished by brief, bulleted content with handy tables and figures, the reference offers all pertinent laboratory and imaging studies needed to confirm a diagnosis, with medication and management guidelines. This guide also describes the most common procedures you will learn during your OB/GYN, including PAP test, colposcopy, labor induction, and cesarean delivery. A special chapter on urgent gynecologic and obstetric conditions, such as placental abruption, sexual assault, and severe uterine bleeding, is also included. Key Features: Provides a pocket-size overview of the PA OB/GYN rotation Describes common clinical presentations, disease entities, and procedures Offers clinical pearls throughout Presents frequently encountered diagnostic studies and their indications Reflects the 2019 NCCPA PANCE blueprint Includes two bonus digital chapters! Three guided case studies to reinforce clinical reasoning plus 25 rotation exam-style questions with remediating rationales Other books in this series: The Physician Assistant Student's Guide to the Clinical Year: Family Medicine; Internal Medicine; Emergency Medicine; Surgery; Pediatrics; Behavioral Health.

Primary care diagnostics involves interpreting and applying information obtained directly from the patient. It re-emphasises the importance of the patient's input into the diagnostic process and of using investigations only after careful consideration has been given to the costs and benefits from both the patient's and the health service's perspectives. The first edition of this book, Patient-Centred Diagnosis, was acclaimed for returning the patient to the centre of diagnostic input and focusing on the interaction between doctor and patient. This revised and augmented new edition, Primary Care Diagnostics, expands on that success; it reflects the broader and equally important issues considered by clinicians or commissioners focusing on the diagnostic approach within primary care, and includes entirely new chapters on cancer and commissioning. Family doctors and other healthcare professionals in the primary care team will find this an enlightening guide. Private and commercial providers of primary care clinical assessment and diagnostic services will also find it of great interest, as will healthcare managers, as well as policy makers and shapers. From reviews of the First Edition: 'Even the more technical sections are expressed in a straightforward language. The style is clear, flowing and engaging. Useful.' THE BRITISH JOURNAL OF GENERAL PRACTICE 'Thought provoking. Clear, understandable and uses real examples from general practice. This is a book for GPs who wish to take a step back from daily practice and think about the reasons behind their actions.' PULSE

Diagnosing Autism Spectrum Disorders: A Lifespan Perspective is the first book of its kind to provide authoritative information for medical and mental health professionals on how to properly evaluate and diagnose autism spectrum disorders in individuals of all ages. * The first book of its kind which demonstrates how to conduct an appropriate diagnostic interview to assess a child for an Autism Spectrum Disorder * Considers the issues of Autism Spectrum Disorders in children, teenagers, and adults * Aimed at both medical and mental health professionals * Includes an in-depth treatment of the entire diagnostic process

Tumors often start out as a benign growth, but gradually progress toward the malignant stage over a relatively long period of time. Tumor progression results from accumulated genetic mutations and inheritable epigenetic modifications that enable clonal evolution and selection of new clonal populations of tumor cells with aggressive characteristics including metastasis and therapy resistance. Increasing amounts of experimental evidence suggests that tumor microenvironment play a significant role in directing clonal evolution and determining clonal cell fate, which eventually leads to emergence of malignant tumor cell clones. Hypoxia is the most commonly observed feature of tumor microenvironment. Tumor hypoxia is significantly associated with malignant progression and predicts poor patient outcomes. This book provides detailed and up-to-date treaties on the role of hypoxia as a major driving force in tumor microenvironment to elicit cellular adaptation and clonal selection via genetic mutations and epigenetic modifications, to facilitate cancer stem cell maintenance, to enhance metastasis, to augment therapy resistance, and to evade immune surveillance.

This issue of Critical Care Nursing Clinics, guest edited by Stephen Krau, PhD, RN, on the topic of Diagnostic Testing will include the following article subjects: Overview of Diagnostic Testing; Electrodiagnostic Testing; Endoscopic Studies; Bronchoscopy Studies; Radiographic Studies; Angiography; Nuclear Scanning Studies; Intravenous Pyleogram;? Manometric Studies; Ultrasound Studies; Urine Tests; Stool Tests; and Centesis Studies.