Five Stars. "Best book available if you want to learn about molecular techniques applied to clinical pathology." - Ruben A., Amazon Reviewer Five Stars. "Easy read. helped me to pass ASCP molecular bio certification exam." - Amazon Reviewer The only book you need to become certified. "Excellent book, full of details and clinical information. In addition, it describes very complexed concepts in a very easy way to understand including comprehensive diagrams." - Ruben G., Amazon Reviewer MB(ASCP) must read. "This is a must read for those laboratory professionals trying to advance their knowledge in molecular diagnostics especially for those people taking the MB(ASCP) exam. Sure it helped me pass the exam." - JR, Amazon Reviewer Meet the challenges of this rapidly expanding field: Molecular diagnostics continues to grow in importance in the clinical laboratory. This respected text will prepare your students with a grounding in the fundamental principles of molecular biology. current methods, and their clinical applications. With a focus on the application of molecular concepts to diagnostic purposes, the text explains and illustrate the use and interpretation of molecular-based assays in patient care. Now with an expanded discussion of nucleic acid sequencing, with added emphasis on next generation sequencing (NGS), and updated coverage of proteomics and mass spectrometry applications, your students will have the most current information available today.

"Bravo to Dr. Sydney Walker. He has written a masterful book for current and prospective mental health consumers. Before filling a prescription for Prozac or Ritalin, make sure you get A Dose of Sanity."—Charles B. Inlander President, People's Medical Society

Has your child been labeled hyperactive?

Has your parent been diagnosed with senile dementia?

Did your doctor prescribe Prozac for your so-called depression?

If you answered "yes" to any of these questions, you need A Dose of Sanity.

Each year, hundreds of thousands of Americans who are actually suffering from common medical conditions such as hyperthyroidism, Lyme disease, and even poor nutrition are misdiagnosed with psychiatric disorders. Studies show that the rate of misdiagnosis is more than 4 in 10.

In this powerful book, practicing psychiatrist Dr. Sydney Walker explains why psychiatric misdiagnosis is so common. More importantly, he helps you and those you love avoid the misdiagnosis trap. Dr. Walker's unique 24-Hour-Day Profile lets you track physical and emotional changes over the course of a day to give your physician valuable clues to what your symptoms really mean.

This book summarizes the results of studies on charge transfer photochemistry of metal complexes of the past few years. The material covered is organized in such a manner that each chapter discusses the photoredox properties of complexes of a series of metals which belong to the same column of the periodic table, including both transition metals and main group metals (for those that show photoactivity). Foremostly, the book covers photoinduced processes in which the primary step is a charge transfer reaction of the excited metal complex. It is concerned primarily with in-depth descriptions and discussions of the photochemistry of complexes themselves, with less emphasis on theoretical discussions.
This book is aimed at professional photochemical researchers as well as students and chemists who are interested in organometallic and inorganic metal complexes and plan to become familiar with their charge transfer photochemistry.

The origin and early years of any rapidly changing scientific discipline runs the risk of being forgotten unless a record of its past is preserved. In this, the first book-length history of clinical chemistry, those involved or interested in the field will read about who and what went before them and how the profession came to its present state of clinical importance. The narrative reconstructs the origins of clinical chemistry in the seventeenth century and traces its often obscure path of development in the shadow of organic chemistry, physiology and biochemistry until it assumes its own identity at the beginning of the twentieth century. The chronological development of the story reveals the varied roots from which modern clinical chemistry arose.

This book provides the most recent findings and knowledge in advanced diagnostics technology, covering a wide spectrum including brain activity analysis, breast and lung cancer detection, echocardiography, computer aided skeletal assessment to mitochondrial biology imaging at the cellular level. The authors explored magneto acoustic approaches and tissue elasticity imaging for the purpose of breast cancer detection. Perspectives in fetal echocardiography from an image processing angle are included. Diagnostic imaging in the field of mitochondrial diseases as well as the use of Computer-Aided System (CAD) are also discussed in the book. This book will be useful for students, lecturers or professional researchers in the field of biomedical sciences and image processing.

The Complete Guide to Ocular History Taking discusses many questions involved in obtaining a complete history of the patient. It offers specific questions for the technician to ask the patient in the exam room and during the history-taking process. This book advises you on condensing a narrative, patient confidentiality, and developing patient rapport. It also provides notes on ocular and systemic medications which will help you look up medications in pharmaceutical references. This text discusses questions regarding ocular and systemic disorders, visual and physical symptoms, and medications. It also covers questions on trauma, gout, arthritis, and diabetes as well as questions for specific groups of patients such as postoperative, pregnant, geriatric, or children. Over 40 common ocular diagnoses are listed with questions to ask at follow-up visits. This text is ideal for on-the-job training or can be used as a handy reference tool while administering an exam. Special Features List of common ophthalmic abbreviations used in history taking. Provides notes on Health Care Financing Administration (HCFA) coding. List of systemic diseases and where they fit under review of systems. Discusses drugs that affect the eye.

In this second edition of The 'Short Cases' section of the clinical examination for membership of the Royal College of Physicians can present candidates with particular difficulties, even though they may have completed Parts 1 and 2 Written Papers successfully. In a short space of time and under the scrutiny of examiners, candidates must carry out physical examinations and correlate their findings on a number of patients. In reviewing 100 of the most commonly encountered short cases, this book will help candidates to develop a methodical, accurate and comprehensive approach to both the patients' and the examiner's questions.

This work focuses on aspects of examining the hand and wrist, from their functional anatomies to peripheral nerve function.

This is the premiere clinical textbook on neonatal ultrasound diagnosis. Profusely illustrated, including Doppler sonographs in color, it contains eleven original new chapters by prominent clinician-teachers from America s foremost medical schools and teaching hospitals. The entire text focuses on definitive, clinically relevant, how-to information on normal neonatal head ultrasound, congenital malformations of the brain, sonography in periventricular leukomalacia and intraventricular hemorrhage, ultrasound of the neonatal gastrointestinal tract, sonographic evaluation of the neonatal biliary system, the neonatal adrenal gland, kidney abnormalities including embryogenesis and imaging appearance, neonatal hydronephrosis, sonography of the neonatal ovary, developmental displacement of the neonatal hip, and sonography of the neonatal spinal canal.

This book describes statistical techniques for the design and evaluation of research studies on medical diagnostic tests, screening tests, biomarkers and new technologies for classification and prediction in medicine.

When teaching neurology to postgraduates the authors found that whilst most students have a good general idea of the different parts of the neurological examination, they are uncertain of the best methods of carrying out the various tests, of the purpose that lies behind them, the true meaning of abnormal findings, how to overcome technical difficulties and avoid arriving at false conclusions. This book is intended to present in detail those methods which have stood the test of time and to select from the newer methods those which are rapidly proving their value. It is not in any sense a textbook of neurology, nor is it a guide to neurological diagnosis. It will however provide the reader to become sufficiently conversant with the technique of examination to be able to approach a neurological case with that confidence which is so often lacking. In the Sixth Edition of this deservedly popular book, the general layout and structure of the chapters has been retained. One chapter has been added on general medical investigation and the chapter on neuroradiology and imaging has been thoroughly rewritten and greatly expanded to take account of the vast technical and theoretical advances in this field, particularly in imaging techniques.

Immunoassay development is a multidisciplinary activity involving a wide range of skills possessed by few laboratories. This presentation of tried and tested methods should enable scientists and researchers in the pharmaceutical and related industries to more rapidly and effectively develop immunoassays upon which their work is becoming heavily dependent.; Important methods are included for preparing Lapten-protein conjugates and raising the necessary antibodies, concentrating on polyclonal sera, as well as methods for the synthesis of radio and enzyme labelled tracers. Particular attention is paid to the requirements of the regulatory authorities such as the FDA (Food and Drug Administration) with respect to assay validation. Further chapters deal with assay development and optimization, curve fitting and quality control procedures.

Psychodiagnosis in Schizophrenia is a reprint of a classic volume in assessment psychology that first appeared in 1966. The book concerns the use of psychodiagnostic techniques in the differential diagnosis of schizophrenia. The author first presents a conceptual analysis of schizophrenic disturbance in terms of impaired ego functioning and extrapolates from schizophrenic ego impairments to psychodiagnostic indices that have been demonstrated to assess them. In particular, Weiner refers to the Wechsler Adult Intelligence Scale, the Rorschach Inkblot Method, and the Draw-A-Person test. Clinical and research data delineating the nature of psychological deficits in schizophrenia are reviewed, and practical guidelines for the clinical assessment of these deficits are presented.
The author next considers several differential diagnostic possibilities frequently considered in the evaluation of schizophrenic persons, with separate chapters devoted to the many forms of schizophrenia, such as: acute, chronic, paranoid, nonparanoid, incipient, remitting, borderline and pseudoneurotic. There are also chapters that focus on schizoaffective disorder and adolescent schizophrenia. The conceptual and empirical contributions to these distinctions are reviewed; accordingly, the differentiating characteristics of these subcategories are related to parameters of psychodiagnostic test performance. In additon, the process of differential psychodiagnosis in schizophrenia is illustrated by detailed case studies. In an extended new preface, the author comments on current perspectives and contemporary literature related to the individual chapters of the text.

Pain is an unfortunate daily experience for many individuals. Chronic pain -- lasting six or more months -- is suffered by approximately 30% of the population in the United States. These individuals wake up, function during the day and go to sleep, trying to keep pain at a minimum while, at the same time, maintaining some quality of life. They may make frequent visits to the doctor and the pharmacy. When they find relief, it is usually short-lived and comes at a cost such as dependence on narcotic medications or complete limitation of activity. Pain often becomes the central point of their existence.
This practice guide describes an approach to psychological evaluation of the chronic pain patient who is being considered for surgery. A large body of research is accumulating which demonstrates that the outcome of surgical procedures aimed at chronic pain relief can be strongly influenced by psychological and emotional factors. This approach, termed "presurgical psychological screening" (PPS) uses interview and testing techniques to identify emotional, behavioral, and psychosocial difficulties which have been demonstrated to negatively impact surgical outcome. Studies show that even patients with clearly identifiable pathophysiology may respond poorly to surgery, due to issues such as pain sensitivity, medication dependence, rewards for pain behavior and personality style. Thus, some insurance carriers, rehabilitation nurses and state worker's compensation systems are encouraging, or even requiring, presurgical psychological screening in cases of surgery designed to relieve chronic pain.
The first to present a comprehensive, unified approach to PPS in chronic pain syndromes, this text is designed to provide the behavioral health practitioner, as well as the trainee, with all the tools and information necessary to conduct PPS evaluations. It identifies a multitude of risk factors for poor surgical outcome and reviews research associated with each risk factor. Hands-on techniques for eliciting information from the patient about risk factors is also detailed. Toward this end, the practice guide also contains a number of forms and session outlines which can be directly utilized, or which can be altered to fit readers' needs. Models for weighing and combining surgical outcome risk factors are also provided. Thus, practitioners are able to reach valid and reliable predictions of surgical results. Finally, the text provides outlines of psychological interventions which can facilitate surgical outcome as well as surgical treatment alternatives. Upon completion of this practice guide, readers should be able to begin providing PPS evaluations which are scientifically valid, clinically sound, and which result in significant overall improvement in the treatment of chronic pain syndromes.

Dialysis amyloidosis is a syndrome observed in dialysis patients characterized initially by joint pain, followed later by joint destruction. It is at present one of the few compliations in these patients. The factors involved in the genesis of this syndrome are not yet known with certainty and there is as yet no proven efficacious treatment otehr then renal transplantation. As a result, the interest in this topic among nephrologists remains very high. Dialysis amyloid gives general information on the pathophysiology, and the clinical aspects of all types of amyloidosis. It then goes on to discuss recently discovered B2, type of dialysis amyloidosis, from clinical and pathological features to physiological and pathophysiological aspects of this serious complication which effects patients suffering from chronic renal failure. This book will give nephrologists and rheumatologists a clear understanding of the dialysis amyloidosis syndrome as well as making a valuable contribution to identifying strategies for treatment and prevention. This book is intended for consultant nephrologists, trainee nephrologists.

This revised and updated second edition is a rhetorical analysis of written communication in the mental health community. As such, it contributes to the growing body of research being done in rhetoric and composition studies on the nature of writing and reading in highly specialized professional discourse communities. Many compelling questions answered in this volume include:
* What "ideological biases" are reflected in the language the nurse/rhetorician uses to talk to and talk about the patient?
* How does language figure into the process of constructing meaning in this context?
* What social interactions -- with the patient, with other nurses, with physicians -- influence the nurse's attempt to construct meaning in this context?
* How do the readers of assessment construct their own meanings of the assessment?
Based on an ongoing collaboration between composition studies specialists and mental health practitioners, this book presents research of value not only to writing scholars and teachers, but also to professional clinicians, their teachers, and those who read mental health records in order to make critically important decisions. It can also be valuable as a model for other scholars to follow when conducting similar long-range studies of other writing-intensive professions.

With the development of rapidly increasing medical imaging modalities and their applications, the need for computers and computing in image generation, processing, visualization, archival, transmission, modeling, and analysis has grown substantially. Computers are being integrated into almost every medical imaging system. Medical Image Analysis and Informatics demonstrates how quantitative analysis becomes possible by the application of computational procedures to medical images. Furthermore, it shows how quantitative and objective analysis facilitated by medical image informatics, CBIR, and CAD could lead to improved diagnosis by physicians. Whereas CAD has become a part of the clinical workflow in the detection of breast cancer with mammograms, it is not yet established in other applications. CBIR is an alternative and complementary approach for image retrieval based on measures derived from images, which could also facilitate CAD. This book shows how digital image processing techniques can assist in quantitative analysis of medical images, how pattern recognition and classification techniques can facilitate CAD, and how CAD systems can assist in achieving efficient diagnosis, in designing optimal treatment protocols, in analyzing the effects of or response to treatment, and in clinical management of various conditions. The book affirms that medical imaging, medical image analysis, medical image informatics, CBIR, and CAD are proven as well as essential techniques for health care.

Informed by more than thirty years of experience, this guide provides a wealth of insight into the clinical observation, diagnosis and treatment of elderly patients. Organized geographically from (literally) head to toes, it concentrates on the basic geriatric physical examination with each chapter providing general information as well as helpful approaches to specific regional complaints. Emphasis is placed on assisting the dedicated clinician in becoming a more perceptive observer of elderly patients with honed skills in geriatric bedside diagnostic evaluation. The text also includes historical vignettes and anecdotes of great physical diagnosticians to demonstrate the evolution of clinical skills. Tables and line drawings complement the text.

For many centuries, people have tried to learn about the state of their health. Initially, in the pre-technological period, they had to rely only on their senses. Then there were simple tools to help the human senses. The discovery of X-rays, which allowed people to look "inside" the body, turned out to be a major breakthrough. Contemporary medical diagnostics is increasingly being assisted by information technology that allows, for example, thorough image tissue analysis or pathology differentiation. They also allow very early preventive diagnostics. Influenced by information technology, "classic" diagnostic techniques change and new ones arise. Information Technology in Medical Diagnostics presents selected and extended conference papers from Polish, Ukrainian and Kazakh scientists. They address problems of the application of new methods of image processing for analysis of medical images, new methods of classification of medical data as well as new medical imaging methods. Some of the presented technologies are inspired by the functioning of living organisms. Information Technology in Medical Diagnostics is of interest not only to academics and engineers, but also to professionals involved in biomedical engineering, and seeking for solutions for issues that cannot be solved with the help of "traditional" technologies.

This straightforward guide to taking patient history comprehensively covers all of the commonly seen OSCE scenarios within the current undergraduate medical curriculum. The Easy Guide to Focused History Taking for OSCEs includes introductory chapters with general OSCE guidance, mapping onto the Calgary-Cambridge model. These include tips from recently qualified doctors and highly respected physicians and surgeons who commonly examine OSCEs, as well as a sample OSCE marking scheme. The book then covers 56 histories based on presenting complaints - more than any other text on the market - thoroughly testing both knowledge and examination technique. Each history is based around the exam requirements, with mnemonics, 'red flag' symptom boxes and list-based breakdowns to aid prompt recall. Common and serious differentials are highlighted, as well as investigations to help rule out the serious conditions. Each section concludes by outlining key aspects for each differential diagnosis as well as a list of investigations and management options. With this book, every student will be well equipped to tackle any clinical problem, in the OSCE examination and also in their continued professional practice.

I found this textbook to be a real bonus for my phlebotomy class. It had plenty of illustrations that complemented the text. I wound up getting an A in the class so I think the book is worth the money!" - Amazon Reviewer "Used this whole training for phlebotomy! Such a helpful informative book!" - Stacy T., Amazon Reviewer "Great book for a phlebotomy class. …lots of tips and warnings along with pertinent information and pictures." - Amazon Reviewer Enter the classroom and the laboratory with confidence! Rely on this comprehensive resource to master the techniques you need to safely obtain quality specimens. You'll understand all the hows and whys that lead to success in this rapidly changing field. Inside, you'll find the up-to-date coverage of routine procedures and their complications as well specialized procedures, quality and infection control, state-of-the-art equipment, medical terminology, ethical and legal issues, body systems, and related diagnostic laboratory tests. Videos and animations online help you to excel.

Updated to reflect changes in the field since publication of the first edition in 1979. Provides a detailed review of the methodology available for assessing the diagnosis and prognosis of cancer patients including data on the application of tumor marker assays and other immunodiagnostic procedures

Addressing the early clinical diagnosis of Alzheimer disease, this book was written to evaluate the relevance of current research on the subject. It uncovers the present lack of clinical utility in research methodologies such as neuro-imaging, drug challenges, electro-encephalographic studies and brain biopsy. The essays addressing each of these issues will provide the reader with a perspective on the role of each technology in clinical practice and an in-depth introduction to the technologies and research findings in each of the areas reviewed.

The extent to which teachers should make use of theoretical and expert knowledge as opposed to tacit experiential knowledge, and how these might be combined, is a perennial issue in discussions on pedagogy. This book addresses these debates through a creative development of the concept of productive uncertainty. Using case studies focusing on teachers working with children with autism, a particularly fertile crucible for considering uncertainty, the book explores how the radical 20th century psychoanalyst Wilfred Bion's epistemological approach to uncertainty can be used to re-frame Donald Schoen's concept of reflection in action, offering a new perspective on the practice of teachers and other caring professionals. Several areas of potential uncertainty are identified, including uncertainty relating to areas of practice including diagnosis, the relationship between expert knowledge and practice, the implications of autism for autonomy and agency, and uncertainties in relation to the understanding of and use of new technologies. A strong argument is made, based on both theoretical and empirical grounds, that in juggling between theoretical and tacit knowledge in the classroom there is more to be gained by staying with the struggle with uncertainty than by fleeing from it too early, into the promise of expert solutions. Consideration is also given to the relative importance of specific theoretical training for teachers, both in general and in relation to working with children with special educational needs, in the context of international and UK policy developments in this area. This book will be of key value to researchers and postgraduates in the fields of education studies, teacher thinking and research, psychoanalytically informed psychosocial studies, as well as to practitioners working in special educational needs/autism education.