The biopsychosocial model for the assessment, diagnosis and treatment of disease has continued to develop since its inception in the mid-twentieth century by Dr. George Engel. The tripartite model is based on general systems theory, and allows for a clinician to get a comprehensive picture of the physical, mental and environmental influences on a patient's health (the authors stress the importance of the concept of an interpersonal clinician-patient relationship). This model of mental health is particularly useful during the initial interviewing and patient presentation processes, during which time the practitioner hopes to gather as much useful information as possible about a new patient.
Interestingly enough, it is often not the collection of data, but the organization, matching, and formulation of information gathered during an interview that presents the clinician with the greater challenge. "The Biopsychosocial Formulation Manual" is intended to help beginning clinicians and trainees to more efficiently gather, organize, assess and diagnose a patient's history and current illness. The manual is designed to first help the clinician with the initial gathering of data, and secondly to later construct a bio-psycho-social formulation. The text is comprised of five major sections (The Biological Formulation, The Psychological Formulation, The Social Formulation, Risk Assessment, and Prognosis). An easy-to-use Biopsychosocial Formulation Database Record is included in the text, giving the reader a useful resource wherein she can record, organize and begin an analysis of data from both patient interview and chart review data. Inserted in each copy of the book will be a companion CD-Romdisc, containing electronic versions of such useful materials as the aforementioned Database Record, many of the tables and charts found within the text, and other valuable tools.

This concise pocket guide to urological investigative procedures reviews the indications and pitfalls of tests before they are requested and suggests which investigations should be performed in individual urological conditions.

Part I describes principles, methodology, advantages and disadvantages of each investigation and covers all urological investigations/tests from simple X-ray of the abdomen (KUB) to PET scanning. Part II offers advice on the choice of investigations for individual urological conditions. For each investigation in Part I and urological condition in Part II, important bullet points are highlighted in a a ~boxa (TM) - useful during a busy ward round, out-patient clinic, or for last-minute consultation prior a viva examination.

This comprehensive yet easy-to-read hadbook is aimed at urological trainees, urology nurse specialists, recently qualified junior urologists as well as practicing urologists as part of review and audit of practices.

Rapid technical advances in medical imaging, including its growing application to drug/gene therapy and invasive/interventional procedures, have attracted significant interest in close integration of research in life sciences, medicine, physical sciences and engineering. This is motivated by the clinical and basic science research requi- ment of obtaining more detailed physiological and pathological information about the body for establishing localized genesis and progression of diseases. Current research is also motivated by the fact that medical imaging is increasingly moving from a primarily diagnostic modality towards a therapeutic and interventional aid, driven by recent advances in minimal-access and robotic-assisted surgery. It was our great pleasure to welcome the attendees to MIAR 2004, the 2nd Int- national Workshop on Medical Imaging and Augmented Reality, held at the Xia- shan (Fragrant Hills) Hotel, Beijing, during August 19 20, 2004. The goal of MIAR 2004 was to bring together researchers in computer vision, graphics, robotics, and medical imaging to present the state-of-the-art developments in this ever-growing research area. The meeting consisted of a single track of oral/poster presentations, with each session led by an invited lecture from our distinguished international f- ulty members. For MIAR 2004, we received 93 full submissions, which were sub- quently reviewed by up to 5 reviewers, resulting in the acceptance of the 41 full - pers included in this volume."

Evidence-based insights into physical signs have evolved and progressed greatly over the past few years, further defining how physical findings identify disease, solve clinical problems, and forecast patient outcomes. Evidence-Based Physical Diagnosis, 5th Edition, is an up-to-date, authoritative resource for guidance on interpreting physical signs, enabling you to determine the most appropriate physical finding to confirm a diagnosis. Incorporating more than 200 new studies, this definitive text helps you glean the most from what you hear, see, and feel at the bedside-information that, combined with modern technologic testing, will grant clinicians the keys to outstanding patient care. Emphasizes the most important physical signs needed to determine the underlying condition or disease. Internationally renowned author Dr. Steven McGee shows readers how to pare down the multiple tests needed to confirm a diagnosis, saving both the physician and patient time and money. Features a reader-friendly outline format, including dozens of "EBM boxes" and accompanying "EBM ruler" illustrations. Contains thorough updates from cover to cover, including new evidence on the scientific value of the Romberg test (spinal stenosis); oximeter paradoxus (cardiac tamponade); platypnea (liver disease); pupil size in red eye (acute glaucoma); hum test (hearing loss); and many more. Begins each chapter with a list of Key Teaching Points, intended for readers desiring quick summaries and for teachers constructing concise bedside lessons. Features a unique evidence-based calculator online that enables you to easily determine probability using likelihood ratios. Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices.

The 7th International Conference on Medical Imaging and Computer Assisted Intervention, MICCAI 2004, was held in Saint-Malo, Brittany, France at the "Palais du Grand Large" conference center, September 26-29, 2004. The p- posaltohostMICCAI2004wasstronglyencouragedandsupportedbyIRISA, Rennes. IRISA is a publicly funded national research laboratory with a sta? of 370,including150full-timeresearchscientistsorteachingresearchscientistsand 115 postgraduate students. INRIA, the CNRS, and the University of Rennes 1 are all partners in this mixed research unit, and all three organizations were helpful in supporting MICCAI. MICCAI has become a premier international conference with in-depth - pers on the multidisciplinary ?elds of medical image computing, comput- assisted intervention and medical robotics. The conference brings together cl- icians, biological scientists, computer scientists, engineers, physicists and other researchers and o?ers them a forum to exchange ideas in these exciting and rapidly growing ?elds. The impact of MICCAI increases each year and the quality and quantity of submitted papers this year was very impressive. We received a record 516 full submissions (8 pages in length) and 101 short communications (2 pages) from 36 di?erent countries and 5 continents (see ?gures below). All submissions were reviewed by up to 4 external reviewers from the Scienti?c Review C- mittee and a primary reviewer from the Program Committee. All reviews were then considered by the MICCAI 2004 Program Committee, resulting in the acceptance of 235 full papers and 33 short communications.

This book provides medical students at the first clinical stage with comprehensive knowledge for the examination subject of clinical chemistry, laboratory diagnostics, hematology, also with regard to exam preparation. A unique feature are the diagrams of cardinal symptoms (19 cardinal symptoms in all, such as pain, temperature, high blood pressure, etc.) which provide a guide from symptom to diagnosis using decision trees. Such overviews are also useful for practicing physicians. The most important methods and techniques are defined in the glossary.

Patient-centered care for chronic illness is founded upon the informed and activated patient, but we are not clear what this means. We must understand patients as subjects who know things and as agents who do things. Bioethics has urged us to respect patient autonomy, but it has understood this autonomy narrowly in terms of informed consent for treatment choice. In chronic illness care, the ethical and clinical challenge is to not just respect, but to promote patient autonomy, understood broadly as the patients' overall agency or capacity for action. The primary barrier to patient action in chronic illness is not clinicians dictating treatment choice, but clinicians dictating the nature of the clinical problem. The patient's perspective on clinical problems is now often added to the objective-disease perspective of clinicians as health-related quality of life (HRQL). But HRQL is merely a hybrid transitional concept between disease-focused and health-focused goals for clinical care. Truly patient-centered care requires a sense of patient-centered health that is perceived by the patient and defined in terms of the patient's vital goals. Patient action is an essential means to this patient-centered health, as well as an essential component of this health. This action is not extrinsically motivated adherence, but intrinsically motivated striving for vital goals. Modern pathophysiological medicine has trouble understanding both patient action and health. The self-moving and self-healing capacities of patients can be understood only if we understand their roots in the biological autonomy of organisms. Taking the patient as the primary perceiver and producer of health has the following policy implications: 1] Care will become patient-centered only when the patient is the primary customer of care. 2] Professional health services are not the principal source of population health, and may lead to clinical, social and cultural iatrogenic injury. 3] Social justice demands equity in health capability more than equal access to health services.

Despite diagnosis being the key feature of a physician's clinical performance, this is the first book that deals specifically with the topic. In recent years, however, considerable interest has been shown in this area and significant developments have occurred in two main areas: a) an awareness and increasing understanding of the critical role of clinical decision making in the process of diagnosis, and of the multiple factors that impact it, and b) a similar appreciation of the role of the healthcare system in supporting clinicians in their efforts to make accurate diagnoses. Although medicine has seen major gains in knowledge and technology over the last few decades, there is a consensus that the diagnostic failure rate remains in the order of 10-15%. This book provides an overview of the major issues in this area, in particular focusing on where the diagnostic process fails, and where improvements might be made.

This text will be of enormous value to anyone involved in the monitoring and investigation of adverse medical events occurring during the clinical trials, or during the post marketing period of a drug. The book reviews the biochemical and physiological abnormalities in each of the bodys organ systems and helps the investigator decide if the problem is of drug-induced origin. Most of the information is presented as a series of observations with accompanying questions which should be addressed in order to make an accurate diagnosis. Easy-to-read with useful flow charts for the management of adverse drug events and examples of specific report forms, this text will be of interest to all those involved in drug monitoring in clinical medicine, pharmaceutical companies, contract research organisations or regulatory authorities.

Molecular Diagnostics: 12 Tests That Changed Everything focuses on specific laboratory tests and emphasizes how the availability of these tests has altered how clinicians treat their patients. Presented as a standard outline, each chapter focuses on a specific molecular test and provides background on the test and its clinical applications. Continuing with some discussion on how the test is done, interpreted, and used clinically, each chapter then concludes with a discussion of how that test has changed the way medicine is practiced with respect to the disease or condition in question. Authored by renowned experts in the field, Molecular Diagnostics: 12 Tests That Changed Everything is a valuable resource for pathologists, pathology residents, laboratory directors, development personnel, lab medicine fellows and those working in the broad area of oncology, infectious disease and genetics.

Since antibodies tagged with markers have been developed, immunocytochemistry has become the method of choice for identifying tissue substances or for the localisation of nucleic acid in tissue by in situ hybridisation. Resin-embedded tissue is routinely used and new techniques are constantly introduced. Thus, the novice entering these fields has a breathtaking variety of methods open to him. This labmanual covers the embedding of tissue using epoxy resin methods to the more sensitive procedures employing the acrylics. The possibilities and results are discussed so that an understanding of the techniques can be acquired and appropriate choices made. The various resins available and all steps involved in tissue processing, beginning with fixation, as well as the great variety of labelling methods and markers that are commonly used for "on-section" cytochemistry and immunocytochemistry are described, including detailed protocols for the application.

What is the probability that a patient with a sore throat has strep? How about the likelihood of DVT in a patient with leg symptoms? What is the prognosis for patients with melanoma, pneumonia, or breat cancer? Covering a full range of topics from cardiovascular and pulmonary disease to ophthalmology, hematology and pediatrics, EVIDENCE-BASED DIAGNOSIS is the only single volume, quick reference designed for use in daily practice. Containing over 150 clinical prediction rules as well as need-to-know background information on each rule to determine its validity and relevance for your practice, these rules are essential for every physician in a time of limited health care resources. Designed as an aid in diagnosis and treatment, clinical prediction rules will allow you to make more accurate diagnosis and treatment decisions while eliminating superfluous testing. As an added bonus, a CD-ROM with software designed by the author is included with this volume. The software is designed to allow you to calculate clinical prediction rules with the ease and convenience of the computer. Simply check the boxes, click enter and receive the probabilities. Mark H. Ebell, M.D., M.S. is Associate Professor in the Department of Family Practice at Michigan State University. He is editor of the "Journal of Family Practice" and coeditor of the "Evidence-Based Practice" newsletter, and is the author of over 80 peer-reviewed publications.

The Third Edition of the Handbook of Current Diagnosis and Treatment provides expert recommendations on the management of more than 200 major medical disorders. Each disorder is condensed into two pages of information using a consistent layout and format that shows diagnosis and treatment guidelines, accompanied by clinical photographs. All contributions are prepared by specialists and contain the most recent reference citations and latest clinical data.

Carpenito's best-selling, Handbook of Nursing Diagnosis, now in an impressive sixteenth edition, is the ideal quick reference for nursing diagnosis information. This handbook offers practical guidance on nursing diagnoses and associated care. The quick-reference type scope of content, makes it easy for students to use while in clinical, in the classroom or simulation lab. From goals to specific interventions, Handbook of Nursing Diagnosis focuses on nursing. It provides a condensed, organized outline of clinical nursing practice designed to communicate creative clinical nursing. It is not meant to replace nursing textbooks, but rather to provide nurses who work in a variety of settings with the information they need without requiring a time-consuming review of the literature. It will assist students in transferring their theoretical knowledge to clinical practice. This is a must-have reference that nursing students will use throughout their curriculum and into their professional career.

Preface This book describes problems and results of research in the gap between two fields: Human genetics, and clinical neurophysiology. Whenever I talked about my research on the genetics of the EEG, the answer of human geneticists was: "Very interesting, but I do not understand anything about the EEG. " On the other hand, EEG specialists usually remark: "Very interesting, but I do not understand anything about human genetics. " This is why I wrote this book. It tries to summarize results my own and from some others - and to point to problems. In the from researc- light of the recent progress especially in human molecular genetics, this field of research promises deep insights into biological mechanisms of brain function, as well as genetic variation involved in mental performance, and personality of humans. However, the logistic problems of such studies are not easy to overcome: It is necessary to study carefully ascertained population samples either of "normal" persons, or of persons selected for phenotypic characteristics that are not easy to diagnose. Moreover, EEG diagnosis and classification must be very specific, and is not trivial at all. All these problems require careful preparations at various levels, long-lasting efforts, and patience. Of this I am sure, however: The results would justify the efforts. I am too old to plan such a program myself; moreover, as an emeritus professor, I do not have the means for such studies.

This syllabus provides a wide overview of the latest developments in diagnostic work and intervention in diseases of the abdomen and pelvis. In addition to conventional diagnostic radiology, special procedures such as US, CT, MRI, nuclear medicine and interventional techniques are discussed.

The 1999 international conference on Information Processing in Medical Imaging (IPMI '99) was the sixteenth in the series of biennial meetings and followed the successful meeting in Poultney, Vermont, in 1997. This year, for the rst time, the conference was held in central Europe, in the historical Hungarian town of Visegr ad, one of the most beautiful spots not only on the Danube Bend but in all Hungary. The place has many historical connections, both national and international. The castle was once a royal palace of King Matthias. In the middle ages, the Hungarian, Czech, and Polish kings met here. Recently, after the summit meeting of reestablished democracies in the area, it became a symbol for the cooperation between central European countries as they approached the European Union. It was thus also symbolic to bring IPMI, in the year of the 30th anniversary of its foundation, to this place, and organize the meeting with the close cooperation of local and traditional western organizers. It also provided a good opportunity to summarize brie?y a history of IPMI for those who were new to the IPMI conference. This year we received 82 full paper submissions from all over the world. Of these, 24 were accepted as oral presentations. These were divided into 6 sessions. In spite of our e orts, it was found to be impossible to make these sessions fully balanced and homogeneous.

Amyotrophic Lateral Sclerosis presents the most comprehensive, clinically-focused information on ALS (Lou Gehrig's disease) in print. The three authors, widely known for their work in this area, provide cohesive and balanced coverage of this syndrome, including the history, clinical features, pathology and pathogenesis, treatment and management of ALS. To facilitate understanding, each chapter is enhanced by comprehensive tables and figures, as well as detailed chapter summaries.

The accurate and reliable diagnosis of transmissible diseases is the most powerful weapon available to ensure their control, and in some cases eradication. The detection of parasites in clinical cases, companion and farm animals, and in the environment is relatively easy since many of them are visible to the naked eye, and those that are not are readily detected by light microscopy. Fungal infections can similarly be determined. Bacteria are somewhat harder to detect. Although their presence can frequently be detected by light microscopy, differential diagnosis, beyond their gross morphology, is almost always impossible. However, most bacterial pathogens can be cultured in the laboratory and can be accurately identified by combinations of a series of simple tests such as morphology, staining, antibiotic sensitivity, biochemical analyses, nutrient dependence, and phage sensitivity. Viruses, however, have proved much more difficult; their size and absolute dependence of the host cell for propagation have rendered useless the methods traditionally used for other microorganisms. Until the development of tissue culture in the middle of this century, diagnosis was entirely dependent on the skill and experience of the clinician. But this was an unreliable process since many of the common virus infections exhibit similar clinical symptoms, such as coryza, exanthema, vomiting, diarrhea, neuralgia, and lethargy. Indeed many viral infections display clinical signs that are indistinguishable from bacterial or parasitic infections.

Organized to serve as a resource for those just beginning to learn EEG as well as those who are already experienced, it contains concise presentations of the fundamentals of EEG technology and interpretation as well as an up-to-date review of the latest digital EEG technology and EEG clinical correlations. Unlike other EEG textbooks, the second half of this book is uniquely organized according to EEG findings rather than individual disorders. This is the best practical approach to learning interpretation because it mirrors the actual practice of EEG, the EEGer is confronted by EEG patterns, not diagnoses. All other textbooks organize findings according to clinical disorder. The book contains sufficient information to serve as a laboratory manual. The appendices contain the American Clinical Neurophysiology Society guidelines for EEG and the International Federation of Clinical Neurophysiology glossary. Each chapter begins with a summary of major concepts. An overview of EEG can be quickly obtained by those beginning the study of EEG by simply reading the introductory summaries of all chapters before reading the contents of the chapters.

14 contributions present mathematical models for different imaging techniques in medicine and nondestructive testing. The underlying mathematical models are presented in a way that also newcomers in the field have a chance to understand the relation between the special applications and the mathematics needed for successfully treating these problems. The reader gets an insight into a modern field of scientific computing with applications formerly not presented in such form, leading from the basics to actual research activities.

The polymerase chain reaction (PCR) is one of the most important molecular biological methods ever devised, with numerous applications to cli- cal molecular medicine. Since its description in 1985, PCR has undergone tremendous improvements, and many variations on the basic PCR theme have been published. With such a large volume of PCR-related literature, a clinical scientist wishing to use the technique will have a difficult task loc- ing the relevant information to implement it effectively. There is thus clearly a need for an up-to-date volume with detailed protocols to facilitate the setting up of those techniques most relevant to clinical applications. Unlike some other books on this topic, Clinical Applications of PCR includes only methods that are of direct relevance in clinical settings. The book is organized in three parts: an introductory section, a section on general methodology, and a final section with specific clinical applications. The first section covers the basic principles of PCR and is most useful to those new to molecular diagnosis. The next chapter includes useful tips for setting up a PCR laboratory. Section 2 then outlines some of the most commonly used PCR-based techniques in molecular diagnosis. Section 3 includes carefully chosen examples that represent typical applications of PCR in diverse clinical fields, encompassing hematology, oncology, genetics, and microbiology.

Preventing Misdiagnosis of Women is a crucial resource for all therapists who treat women. Not only will the information further the well-being of women clients, but it could literally save lives. Interesting, readable, and well-organized, this book belongs on the shelf next to the DSM-IV. The case examples will grip the reader whether professional or lay audience. --Natalie Porter, Ph.D., California School of Professional Psychology "I am greatly impressed with the book. It is a brand new idea, one that is long overdue." --Hannah Lerman, Ph.D., Clinical Psychologist, Los Angeles Some clients don't respond to a therapist's chosen treatment for a specific mental disorder. Could there be a physical disorder that is causing psychiatric symptoms? How can a therapist distinguish between similar psychiatric and physical disorders to arrive at the correct diagnosis, refer on, and/or suggest appropriate treatment? Preventing Misdiagnosis of Women gives the therapist the foundation for identifying those physiological disorders that may be at the root of the mental problems presented by women clients. Hyperthyroidism, for example, can result in depression and anxiety, and temporal lobe epilepsy can manifest itself with the same symptoms as bipolar disorder. This special guidebook sorts out potential mix-ups by providing detailed cases and illustrations, a quick reference table for checking symptoms, and a glossary. Making technical information clear and concise, the authors cover endocrinological--including thyroid, adrenal, pituitary, and parathyroid systems--and brain seizure problems as well as other diseases--such as multiple sclerosis, mitral heart valve prolapse, and lupus erythematosus. They offer a basic overview of the systems and organs involved and focus on how particular malfunctions can result in serious behavioral problems. A guide to providing the best and most effective care to women clients, Preventing Misdiagnosis of Women presents important information about assessment and interfacing with medical professionals. All mental health and helping professionals will find this book invaluable, as will students in clinical/counseling psychology, health psychology, social work, and gender studies. "This book is informative and interesting to read. This is a text that can be read more than once and be that much more helpful in subsequent readings. . . . Preventing Misdiagnosis of Women will certainly have an impact on feminist assessment, theory, and therapy. In a broader context, it provides a foundation to spawn research hypotheses on women's health and to reconnect the mind and body. Written accessibly even for reader without a background in physiological psychology, it fills a gap in the clinical and counseling literature. This text has far-reaching implications about the origin of psychiatric symptoms and possibly for explaining some differential rates in sex ratios for prevalence of certain psychologically based clinical syndromes. I found the text a humbling reminder of how easy it can be to miss the obvious and how easy it can be to attribute psychological explanations to symptom clusters one doesn't understand. This book could easily become a 'required' text for graduate students in mental health professions and mental health professionals. . . . This text will undoubtedly have an impact." --Maria P. P. Root, Ph.D., University of Washington "Preventing Misdiagnosis of Women is very good and will make an important contribution to the field. . . . The book's message--that it is critical that differential diagnosis include consideration of both psychiatric disorders--is convincing and important to emphasize to students in graduate programs." --Helene Jackson, Ph.D., The Columbia University School of Social Work