Sexual problems are a major cause of personal distress and marital breakdown, affecting as many as one in ten of the general population. The author, who has had extensive clinical, research, and teaching experience in the field of sexual dysfunction, has written a very practical account of the nature, causes, assessment, and treatment of sexual problems. The various stages of treatment are described in sufficient detail for therapists who are about to start sex therapy. Experienced therapists will also find this book a source of useful advice. The treatment approach includes behavioural, psychotherapeutic, and educational techniques. In addition to the treatment of couples, the management of sexual problems of individuals without partners, and of the phsyically disabled, are also described. Practical guidance is backed up by research findings. This book is an up-to-date, straightforward, and practical account which should be of considerable interest to anyone involved in the management of sexual problems.

"Limb X-Ray Interpretation" provides a comprehensive guide to limb X-ray trauma diagnosis. The content is separated into two distinct parts; part I addresses the technical and professional issues in trauma radiography, from the initial request for an examination to the final image, including the normal and abnormal appearance of bone on radiographs and the classifications of fractures. Part II is subdivided into distinct anatomical regions by chapter describing a systematic approach to the interpretation of X-ray images.

Each chapter follows a similar format with core anatomy linked to the normal radiographic anatomy, using over 570 X-ray images and line drawings. The common and less common fractures, together with specific radiological signs of abnormalities, mechanism of injury and subsequent treatments are presented.

This book is of of great value to Emergency Nurse Practitioners, Accident and Emergency staff, radiographers, junior doctors, medical students, and physiotherapists.

This work presents an unflinching look inside the detective story that marks nearly every illness - the diagnosis - revealing the combination of uncertainty and intrigue that doctors face when confronting patients who are sick or dying.

This book presents different experimental results as evidence of the good results obtained compared with respect to conventional approaches and literature references based on fuzzy logic. Nowadays, the evolution of intelligence systems for decision making has been reached considerable levels of success, as these systems are getting more intelligent and can be of great help to experts in decision making. One of the more important realms in decision making is the area of medical diagnosis, and many kinds of intelligence systems provide the expert good assistance to perform diagnosis; some of these methods are, for example, artificial neural networks (can be very powerful to find tendencies), support vector machines, that avoid overfitting problems, and statistical approaches (e.g., Bayesian). However, the present research is focused on one of the most relevant kinds of intelligent systems, which are the fuzzy systems. The main objective of the present work is the generation of fuzzy diagnosis systems that offer competitive classifiers to be applied in diagnosis systems. To generate these systems, we have proposed a methodology for the automatic design of classifiers and is focused in the Generalized Type-2 Fuzzy Logic, because the uncertainty handling can provide us with the robustness necessary to be competitive with other kinds of methods. In addition, different alternatives to the uncertainty modeling, rules-selection, and optimization have been explored. Besides, different experimental results are presented as evidence of the good results obtained when compared with respect to conventional approaches and literature references based on Fuzzy Logic.

In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease.

Since the Human Genome Project was completed in 2003, the price of genome sequencing has dropped at a staggering rate. It’s as if the price of a Ferrari went from $350,000 to a mere forty cents. Through breakthroughs made by Dr. Ashley’s team at Stanford and other dedicated groups around the world, analyzing the human genome has decreased from a heroic multibillion dollar effort to a single clinical test costing less than $1,000.

For the first time we have within our grasp the ability to predict our genetic future, to diagnose and prevent disease before it begins, and to decode what it really means to be human.

In The Genome Odyssey, Dr. Ashley details the medicine behind genome sequencing with clarity and accessibility. More than that, with passion for his subject and compassion for his patients, he introduces readers to the dynamic group of researchers and doctor detectives who hunt for answers, and to the pioneering patients who open up their lives to the medical community during their search for diagnoses and cures.

He describes how he led the team that was the first to analyze and interpret a complete human genome, how they broke genome speed records to diagnose and treat a newborn baby girl whose heart stopped five times on the first day of her life, and how they found a boy with tumors growing inside his heart and traced the cause to a missing piece of his genome.

These patients inspire Dr. Ashley and his team as they work to expand the boundaries of our medical capabilities and to envision a future where genome sequencing is available for all, where medicine can be tailored to treat specific diseases and to decode pathogens like viruses at the genomic level, and where our medical system as we know it has been completely revolutionized.

Musculoskeletal Examination is a user-friendly textbook on the techniques of physical examination. Written by a physiatrist, orthopedic surgeon, and physical therapist, it has a uniquely multidisciplinary approach. Musculoskeletal Examination covers the complete basic examination and basic principles of normal and abnormal musculoskeletal function are fully explained, leading you to the correct differential diagnosis. The new fourth edition is now in full colour throughout and includes over 750 detailed illustrations, X-rays and MRIs, and more than 100 photographs showing examination techniques. It also includes a companion website at www.wiley.com/go/musculoskeletalexam featuring 107 MCQs and links to videos demonstrating key examination methods. Musculoskeletal Examination is perfect as a quick reference guide, while the detailed descriptions and clinically relevant examples of frequently encountered conditions will help even the most novice practitioner gain the understanding necessary to make a correct diagnosis and determine a successful treatment plan. It is ideal for physical therapists, physiatrists, orthopedists, medical students, practitioners, and all those involved in sports medicine and clinical massage.

This volume presents several machine intelligence technologies, developed over recent decades, and illustrates how they can be combined in application. One application, the detection of dementia from patterns in speech, is used throughout to illustrate these combinations. This application is a classic stationary pattern detection task, so readers may easily see how these combinations can be applied to other similar tasks. The expositions of the methods are supported by the basic theory they rest upon, and their application is clearly illustrated. The book's goal is to allow readers to select one or more of these methods to quickly apply to their own tasks. Includes a variety of machine intelligent technologies and illustrates how they can work together Shows evolutionary feature subset selection combined with support vector machines and multiple classifiers combined Includes a running case study on intelligent processing relating to Alzheimer's / dementia detection, in addition to several applications of the machine hybrid algorithms

Written by authors who are hospitalists and clinician-educators, Cases in Hospital Medicine uses practical case studies and current medical evidence to guide you expertly through the types of cases seen most often by practicing hospital-based clinicians. This engaging handbook covers the wide range of both broad and specific knowledge required in the hospital environment, while focusing on highly relevant questions and today's best practices. You'll find real-world guidance on essential topics, including commentary on research studies and clinical guidelines. Provides an evidence-based approach to clinical cases most often encountered by hospitalists, including the key questions in these situations, such as: What sort of diuretic regimen-bolus or continuous infusion-should I use to remove fluid from a 73-year-old man with acute congestive heart failure? How soon should a 49-year-old woman with gallstone pancreatitis undergo prophylactic cholecystectomy? What are the risks and benefits of continuing aspirin therapy perioperatively in patients undergoing noncardiac surgery? What is the optimal anti-inflammatory agent for a 60-year-old man with acute gouty arthritis? Maintains a clinical focus throughout, discussing the most practice-relevant questions for hospital-based clinicians and providing answers to specific clinical dilemmas. Covers a wide variety of frequently-seen situations such as skin and soft tissue infection, pneumonia, alcohol withdrawal, sepsis, COPD exacerbation, syncope, atrial fibrillation, pancreatitis, acute kidney injury, end-of-life care, and much more. Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

Selected as a Doody's Core Title for 2022! Now in a fully revised 4th Edition, Modern Epidemiology remains the gold standard text in this complex and evolving field, offering unparalleled, comprehensive coverage of the principles and methods of epidemiologic research. Featuring a new, full-color design, updated models, and a new format allowing space for margin notes, this edition continues to provide authoritative information on the methodologic issues crucial to the wide range of epidemiologic applications in public health and medicine. Reflects both the conceptual development of this evolving science and the increasing role that epidemiology plays in both public health and medicine. Features a new full-color design, new coverage of marginal structural models, new instrumental variable analysis, updated structural nested models, and more. Covers a broad range of concepts and methods, including epidemiologic measures of occurrence and effect, study designs, validity, precision, statistical interference, field methods, and causal diagrams. Includes data analysis topics such as Bayesian analysis, sensitivity analysis, and bias analysis, with an extensive overview of modern regression methods including logistic and survival regression, splines, hierarchical (multilevel) regression, propensity scores and other scoring methods, and g-estimation. Discusses special topics such as disease surveillance, ecologic studies, social epidemiology, infectious disease epidemiology, genetic and molecular epidemiology, nutritional epidemiology, environmental epidemiology, reproductive epidemiology, clinical epidemiology, and meta-analysis. Coauthored by three leading epidemiologists, with contributions from experts in a variety of epidemiologic sub-disciplines.

In recent years, imaging has rapidly become a tremendously valuable approach in nearly every field of biological research. Finding the right method and optimizing it for data collection can be a daunting process, even for an established imaging laboratory. Imaging: A Laboratory Manual is the cornerstone of a new laboratory manual series, designed as an essential guide for investigators who need these visualization techniques. This first volume is meant as a general reference for all fields, and describes the theory and practice of a wide array of imaging methods. From the basic chapters on optics, equipment and labeling to detailed explanations of advanced, cutting-edge methods like PALM, STORM, light sheet and high speed microscopy, Imaging: A Laboratory Manual is a vital resource for the modern biology laboratory.

The announcement of a serious diagnosis is a solemn moment when directions shift, priorities change, and life appears in sharper focus. It is also a moment when a story takes shape. It is a story we are able to imagine, even if we haven't experienced it firsthand, because the moment of diagnosis is as pervasive in popular media as it is in medicine. Diagnosis: Truths and Tales shares stories told from the perspectives of those who receive diagnoses and those who deliver them. Confronting how we address illness in our personal lives and in popular culture, this compelling book explores narratives of diagnosis while pondering the impact they have on how we experience health and disease.

This innovative handbook bridges the gap between the colorectal surgeon, the stoma nurse and the dermatologist. It addresses the questions of what pathology is involved, what can be done by nurses, when to refer to a dermatologist, and what can be done by a dermatologist. Now in its second edition, the book has been revised throughout and contains new information on nutrition and child stoma patients.

A practical, real-world approach-focus on what's normal to identify abnormal. Here are all of the how-tos, what-tos, when-tos, and why-tos you need to master in a well-organized, well-illustrated text that makes the material easier to learn now... and reference later. First, it focuses on the normal and the normal variants of the adult, child, elderly, and pregnant patients seem most frequently in practice. Then, when a finding falls outside of those parameters, you'll be able to identify it as abnormal. Second, assessment is presented as a linear and consistent process, so you will always do the same steps in the same order, assuring that you don't miss anything. An access code inside new, printed texts unlocks resources online at FADavis.com, including Advanced Assessment Techniques, an Audio Library with sample auscultation and percussion sounds, Case Studies featuring real-life scenarios, and Performance Checklists that document the steps of each technique.

Because principles of nursing process are the building blocks for all care models, the nursing process is the first model nurses need to learn to "think like a nurse." This trusted resource provides the practical guidance needed to understand and apply each phase of the nursing process, with an increased emphasis on developing both critical thinking and clinical reasoning skills. With an easy-to-follow and engaging writing style, the author provides strategies, tools, and abundant examples to help nurses develop the skills they need to thrive in today's complex health care setting.

This manual is a practical, illustrated how-to guide to the proper techniques and electrode placements for common nerve conduction studies. The first section describes each nerve conduction study, including placement of electrodes, typical electromyography equipment settings, normal values, and pearls and pitfalls. The second section provides detailed coverage of surface anatomy for needle electromyography and shows where to place the needles for each muscle. More than 200 clear photographs demonstrate correct placement of needle electrodes. Chapters in each section follow a consistent sequence and are written in outline format to help readers find information quickly.

The book discusses novel visualization techniques driven by the needs in medicine and life sciences as well as new application areas and challenges for visualization within these fields. It presents ideas and concepts for visual analysis of data from scientific studies of living organs or to the delivery of healthcare. Target scientific domains include the entire field of biology at all scales - from genes and proteins to organs and populations - as well as interdisciplinary research based on technological advances such as bioinformatics, biomedicine, biochemistry, or biophysics. Moreover, they comprise the field of medicine and the application of science and technology to healthcare problems. This book does not only present basic research pushing the state of the art in the field of visualization, but it also documents the impact in the fields of medicine and life sciences.

Concise, portable, and user-friendly, The Washington Manual (R) General Internal Medicine Consult, Third Edition , provides quick access to the essential information needed when performing an inpatient consult. Chapters are organized around presenting symptom (e.g., approach to nausea, approach to low back pain), allowing quick look-up of differential diagnosis and management. Ideal for medical students, residents, and practitioners, the manual is also useful as a quick-reference guide for practicing hospitalists. Key Features: Brief, focused information throughout, zeroing in on the essential diagnosis and assessment information you need for an internal medicine consult. Thoroughly revised to include new approaches to diagnosis and new therapeutic management, as well as an all-new chapter on venous thromboembolic disease. Organized by presenting symptom, making information easy to find so you can maximize your time spent during the consult. Perfect for residents asked to perform a medical consult, hospitalists, students, NPs, and PAs. Written by residents, fellows, and attending physicians from the Washington University School of Medicine in St. Louis. Your book purchase includes a complimentary download of the enhanced eBook for iOS, Android, PC & Mac. Take advantage of these practical features that will improve your eBook experience: The ability to download the eBook on multiple devices at one time - providing a seamless reading experience online or offline Powerful search tools and smart navigation cross-links allow you to search within this book, or across your entire library of VitalSource eBooks Multiple viewing options offer the ability to scale images and text to any size without losing page clarity as well as responsive design The ability to highlight text and add notes with one click

Selected as a Doody's Core Title for 2021! An excellent resource for appropriate test ordering and interpretation, Wallach's Interpretation of Diagnostic Tests, 11th Edition, helps you save time, avoid errors, and arrive at an accurate diagnosis. Organized into two easy-to-reference sections, this fully revised manual provides comprehensive, practical information on common and uncommon disease states and their diagnosis by laboratory test. The eleventh edition has been revised and reorganized based on reader feedback, helping primary care physicians, subspecialists, physician assistants, nurse practitioners, and medical and nursing students keep pace with a rapidly changing health care environment. An easy-to-use organization presents routine and lesser known lab tests first (alphabetically, with detailed descriptions), with disease states following. Newly concise and streamlined content is highlighted by abundant tables, algorithms, and bulleted lists and checklists. A new pull-out card, "Ask Before You Test," helps you remember to check key factors that affect lab tests. Content updates include new information in the genetic, molecular diagnostics, and neurology testing chapters. Frequently ordered tests are included in tabular form, as well as in a tear-out version for convenient clinical use. An expanded index helps you efficiently locate needed information. Enrich Your Ebook Reading Experience Read directly on your preferred device(s),such as computer, tablet, or smartphone. Easily convert to audiobook,powering your content with natural language text-to-speech.

Following the highly successful model of the first edition, "Pocket Guide to ECG Diagnosis, 2e" describes every known common ECG abnormality and cardiac arrhythmia with a practical and clinical approach. On the left page of the book, each abnormality is described precisely and concisely, including definition, diagnostic criteria, and diagnostic pearls. On the right page, a crystal clear reproduction of a given ECG abnormality is shown. This at-a-glance format makes this Pocket Guide effective for quick interpretation of ECGs. Dr. Ching has updated and revised the entire book and included over 20 new ECGs in this edition.

In this book, a new approach for diagnosis and risk evaluation of ar-terial hypertension is introduced. The new approach was implement-ed as a hybrid intelligent system combining modular neural net-works and fuzzy systems. The different responses of the hybrid system are combined using fuzzy logic. Finally, two genetic algo-rithms are used to perform the optimization of the modular neural networks parameters and fuzzy inference system parameters. The experimental results obtained using the proposed method on real pa-tient data show that when the optimization is used, the results can be better than without optimization. This book is intended to be a refer-ence for scientists and physicians interested in applying soft compu-ting techniques, such as neural networks, fuzzy logic and genetic algorithms, in medical diagnosis, but also in general to classification and pattern recognition and similar problems.

This book will enable practitioners to understand the many complex intricacies of immunohistochemistry (IHC) and make best use of this powerful analytical tool. Providing a thorough grounding in the fundamentals of immunohistochemistry, the book includes several chapters on robotics and automation technology, giving key information on the design of machines and tips to maximise workflow efficiencies. The relationship between IHC and molecular pathology is explained clearly, demonstrating the increasing impact on personalized medicine and targeted therapies for cancer patients. The staining protocol is deconstructed, allowing the reader to adapt it for a variety of diagnostic and research applications. Written by experts at the forefront of hospital immunohistochemistry, there is a strong emphasis on practical guidance on a range of techniques as well as troubleshooting of common problems driven by the authors' experiences. Extensively illustrated with high-quality colour images, this is an invaluable resource to all pathology practitioners utilising the technique.

The majority of tropical diseases manifest themselves through the skin, and while many can be diagnosed on physical examination, dermatopathologic results are often of critical importance to the diagnostic process. However, general dermatopathology texts lack images of diseases endemic in the developing world; they also lack clinical correlates linking the pathology to the clinical entity. This is a problem, because greater movement between countries where tropical diseases are prevalent and Europe, North America and other developed nations makes it essential for physicians to be able to recognize, diagnose and treat these diseases. Dermatopathology of Tropical Diseases covers the pathology and clinical correlations of the most important tropical diseases. Each entity is described using brief text that summarises its epidemiology, pathogenesis and clinical features. The diagnostic process is then described and illustrated using both clinical and histopathologic images. Wherever possible, different examples are shown of the same disease, in order to illustrate as wide a variety of presentations as possible. Extensively illustrated with almost 600 photographs, Dermatopathology of Tropical Diseases is an invaluable resource for dermatopathologists, pathologists and dermatologists based in the developing world as well as those in developed countries who see tropical diseases in returned travellers and immigrant populations. Key features Includes chapters on all major tropical diseases, with both clinical and histopathological images provided for each entity, allowing the reader to correlate pathological characteristics with the clinical presentation of each disease Wherever possible, different examples of the same disease are shown, to illustrate the variety of presentations Lavishly illustrated with almost 600 colour photographs

This concise reference clarifies the gray areas between traumatic brain injury and PTSD while providing an empirically sound framework for neuropsychological evaluation and differential diagnosis. Its extended research review summarizes findings on key topics including the neuroanatomy of brain injury, test battery design and selection, and the salience of accurate diagnosis to ensuring appropriate specialized treatment. The authors offer the possibility of combined diagnosis as well as injuries that may fall through the diagnostic cracks, and consider possible relationships between TBI, PTSD, and the dementias, including Alzheimer's disease. This knowledge base and the practical guidelines it informs are presented so that readers can better: * Understand the clinical distinctions between TBI and PTSD, and among forms of TBI. * Recognize cognitive, behavioral, emotional, and social components of the disorders. * Identify skill areas for neuropsychological evaluation of patients. * Select appropriate instruments for individualized assessment.* Address test administration and interpretation concerns. * Make an accurate differential diagnosis between PTSD and TBI. With its sharp focus on the nuances of trauma and recovery, The Intercorrelation of Traumatic Brain Injury and PTSD in Neuropsychological Evaluations will find a wide, interested audience among psychologists, neuropsychologists, neurologists, psychiatrists, social workers, mental health counselors, undergraduate and graduate level students, and researchers. In addition, this text may be useful for those interested in psychology and neurology. <

Immunoassays Edited by R. Edwards Immunoassays are among the most widely used of analytical techniques and have been applied successfully to an extensive range of substances, from single molecules to whole cells. This book provides key data on all types of immunoassay, including RIA, ELISA and dry surface immunoassays, and on the use of photoluminescent and chemiluminescent labels in immunoassays. Essential information is also given on assay design and data processing. The Essential Data series provides rapid access to the core data required by researchers on a daily basis, in convenient pocket-sized volumes.