Many inherited diseases and non-herediatry disorders have in common the development of renal cyctic disease. The most common, autosonal dominant polycystic kidney disease, is responsible for 5-10% of end-stage renal failure treated by dialysis or transplantation.
Since the publication six years ago of the last book on polycystic kidney disease, a number of genes causing the disease have been identified, mapped, or sequenced; new experimental models and the application of molecular biology techniques have provided new insights into the pathogenesis of polycystic kidney disease; novel clinical studies have provided valuable information for the prevention, evaluation, and treatment of the complications of this disease. This book provides an updated, state-of-the-art review of the genetics, pathophysiology, evaluation, and management of these diseases and will be of interest to both basic researchers and clinicians in nephrology.

Dialysis amyloidosis is a syndrome observed in dialysis patients characterized initially by joint pain, followed later by joint destruction. It is at present one of the few compliations in these patients. The factors involved in the genesis of this syndrome are not yet known with certainty and there is as yet no proven efficacious treatment otehr then renal transplantation. As a result, the interest in this topic among nephrologists remains very high. Dialysis amyloid gives general information on the pathophysiology, and the clinical aspects of all types of amyloidosis. It then goes on to discuss recently discovered B2, type of dialysis amyloidosis, from clinical and pathological features to physiological and pathophysiological aspects of this serious complication which effects patients suffering from chronic renal failure. This book will give nephrologists and rheumatologists a clear understanding of the dialysis amyloidosis syndrome as well as making a valuable contribution to identifying strategies for treatment and prevention. This book is intended for consultant nephrologists, trainee nephrologists.

This book introduces the reader to the basic skills necessary for good communication between doctors (and other health professionals) and patients. The practical importance of such skills is outlined, making the doctor much more effective in all fields of medicine. This is not a book for the specialist reader, but aimed at all those who need to talk with patients.

There is currently a great deal of interest in patients with functional somatic symptoms--physical complaints which are not explained by organic findings--but until now there has been little information available on the principles and practical methods of their treatment. This book covers all the key topics in the management of somatic disorders, and will be invaluable both as a comprehensive reference and as a practical clinical guide. The authors have included material on the problems specific to children and the elderly, the organization of service provision, as well as the clinical syndromes characteristic of somatic disorders such as hypochondriasis, chronic pain, chronic fatigue, and low back pain.
Treatment of Functional Somatic Symptoms is the first comprehensive, authoritative and practical guide on the management of a wide variety of medically unexplained symptoms encountered frequently in all areas of primary and hospital care. The book will be useful to clinicians and to research workers as a source book and a clinical manual.

Objective structured clinical examinations/exercises (OSCEs) using standardized patients (SPs) are an efficient means of surveying a diverse range of ability at any point along the continuum of medical education. An OSCE station can address multiple competency assessments across undergraduate, graduate, and continuing medical education. Nevertheless, organizing and enacting OSCEs is a major undertaking and, as with most other educational projects, collaborating within and across specialties and disciplines only enriches the process. The production of an effective OSCE program requires strong leaders committed to the benefits of such assessments, as well as many individuals to plan, prepare, and implement the program. To address the need for general guidelines of best practice and consistent organizational stratagem, Objective Structured Clinicl Exams is a comprehensive how-to manual for OSCE implementation. It contains an overview of and criteria for best practice, a review of relevant literature, insight into the program's influence throughout the healthcare system, and techniques for fine-tuning existing programs. Accompanying charts, graphs and sample forms are included to make this book the single resource for any educator interested in creating or improving a standardized patient program.

Il libro prende le mosse dai pensieri di un giovane che alla maturita liceale si trova affascinato dalla cultura dei classici greco-latini, dai rudimenti filosofici e dall impatto con le scienze fisiche e naturali. Il latino e i suoi naturalisti hanno suscitato un fervore verso la Botanica Sistematica che lo riporta a Linneo e quindi alla conoscenza del mondo naturale, all esperienza della denominazione dell esistente come conoscenza e quindi agli universali di Guglielmo d Occam. La scelta della facolta di Medicina fungera da mediazione fra la filosofia, vista come via alla verita, e la biologia con il grande mistero dell uomo nella sua dualita di mente/corpo. L incontro con il microscopio aprira la strada all approfondimento della biologia, ma anche alla ricerca dei significati e delle interpretazioni del mondo. I meccanismi della percezione, visiva in particolare, nelle articolazioni della Gestaltpsychologie, e i suoi rapporti con il mondo interiore, sia quello della memoria esplicita che della memoria implicita, sono affrontati nell esplorazione del mondo attraverso il microscopico e nella ricerca di una obiettivita scientifica. Locke e Kant, Popper e Heidegger fanno da contraltare a Ramon y Cajal, Golgi, Kandel, Heisenberg, mentre la semiotica illumina e confonde sull importanza del linguaggio per la conoscenza. Il segno e il suo riconoscimento si trasferiscono nella scienza attraverso l inter-soggettivita e il linguaggio appare come l unico modo di penetrare l esistente. Il libro si dilunga sull origine di certe denominazioni in patologia tratte dalla vita quotidiana, sull antropomorfismo spesso applicato agli oggetti del campo microscopico, sempre illustrati su base fenomenologica e psicologica.

Rapid advancement of telecommunications and information technology has created the potential for high-quality expert healthcare to be delivered when and where it is needed. This text charts the development of the telemedicine industry, defines its current scope and reveals the potential of new methodologies.

• Explains the main features of telemedicine and telecare
• Reviews the technology needed for telemedicine
• Describes how to develop, deliver and evaluate telemedicine services
• Considers the associated ethical and legal issues
• Includes an in-depth survey of the literature with over 300 references to research articles and hyperlinks to associated websites

Updated with new treatments and algorithms, ECG Facts Made Incredibly Quick! Second Edition provides instant access to information that every nurse needs for safe patient care. The book fits comfortably into a pocket, and the wipeable page surface allows nurses to write notes and remove them easily. Coverage includes basic electrocardiography including cardiac conduction, lead placement, and heart rate calculation; rhythm strip interpretation; causes, signs and symptoms, interventions, and treatment for arrhythmias; 12-lead and 15-lead ECG interpretation; ECG changes with angina, MI, pericarditis, and bundle branch block; and antiarrhythmic drugs, pacemakers, and ICDs. Scores of ECG waveforms, treatment algorithms, and charts are included. Distinctive-colored tabs identify each section.

In order to accurately describe and diagnose psychiatric illness, practitioners require in-depth knowledge of the signs and symptoms of behavioral disorders. Descriptive Psychopathology provides a broad review of the psychopathology of psychiatric illness, beyond the limitations of the DSM and ICD criteria. Beginning with a discussion of the background to psychiatric classification, the authors explore the problems and limitations of current diagnostic systems. The following chapters then present the principles of psychiatric examination and diagnosis, described with accompanying patient vignettes and summary tables, and related to different diagnostic concerns. A thought-provoking conclusion proposes a restructuring of psychiatric classification based on the psychopathology literature and its validating data. Written for psychiatry and neurology residents, clinical psychologists, behavioral neurologists, clinical psychology students and psychiatric nurse practitioners, it is invaluable to anyone who accepts the responsibility for the care of patients with behavioral syndromes.

A revision and reference text for pre-registration and postgraduate optometrists, covering procedures for investigating heterophoria, heterotropia, vergence and accommodative anomalies. The text covers the diagnosis of disorders of voluntary eye movement, nystagmus and supranuclear defects, paresis and non-paralytic incomitancy. Both motor and sensory anomalies are discussed together with syndromes involving oculomotor anomalies. Clinical management is outlined in protocols in an easily assimilable form. The second edition has additional information for final year undergraduates. Amblyopia treatment has been extended to cover new American optometric methods. Strabismus surgical techniques are now included. There are two new chapters on vision training and case management which will interest optometrists and orthoptists involved in sports vision and in developmental vision therapy. Pre-registration optometrists will find the chapters on routine orthoptic assessment and the PQE examination of particular interest.

This book is a practical guide to the diagnosis, pathophysiology and management of cardiac disorders. Beginning with an overview of symptoms and signs of cardiopulmonary diseases, the following chapters cover treatment options for different disorders. New strategies for the treatment of Type 2 diabetes are discussed in depth. The final section explains a new method for obtaining better quality recordings from ECGs. Authored by an Ontario-based specialist in cardiology, this comprehensive manual is illustrated with clinical images and figures. Key points Practical guide to diagnosis, pathophysiology and management of cardiopulmonary disorders Provides overview of signs and symptoms Presents new strategies for treatment of Type 2 diabetes Authored by Ontario-based specialist in cardiology

Concise, portable, and user-friendly, The Washington Manual (R) General Internal Medicine Consult, Third Edition , provides quick access to the essential information needed when performing an inpatient consult. Chapters are organized around presenting symptom (e.g., approach to nausea, approach to low back pain), allowing quick look-up of differential diagnosis and management. Ideal for medical students, residents, and practitioners, the manual is also useful as a quick-reference guide for practicing hospitalists. Key Features: Brief, focused information throughout, zeroing in on the essential diagnosis and assessment information you need for an internal medicine consult. Thoroughly revised to include new approaches to diagnosis and new therapeutic management, as well as an all-new chapter on venous thromboembolic disease. Organized by presenting symptom, making information easy to find so you can maximize your time spent during the consult. Perfect for residents asked to perform a medical consult, hospitalists, students, NPs, and PAs. Written by residents, fellows, and attending physicians from the Washington University School of Medicine in St. Louis. Your book purchase includes a complimentary download of the enhanced eBook for iOS, Android, PC & Mac. Take advantage of these practical features that will improve your eBook experience: The ability to download the eBook on multiple devices at one time - providing a seamless reading experience online or offline Powerful search tools and smart navigation cross-links allow you to search within this book, or across your entire library of VitalSource eBooks Multiple viewing options offer the ability to scale images and text to any size without losing page clarity as well as responsive design The ability to highlight text and add notes with one click

Chinese Medicine constantly refers back to its sources in order to initiate the new. Its source code is in the Han Dynasty medical classics, and in this handbook esteemed practitioner and educator Professor Z'ev Rosenberg shares the knowledge from his study of these classic texts and his experiences treating difficult cases. In the tradition of the scholar-physician commentaries, Z'ev Rosenberg comments on the Simple Questions that introduce the core principles of the Inner Canon; explaining how these inform his methodology of diagnosis and advising on how biomedical diseases can be retranslated into sophisticated Chinese medical diagnoses including patterns of differentiation, sequential diagnosis, synchronicity, season, climate and environment. He discusses how Chinese medicine can use unique diagnostic parameters to rebalance the landscape and chronobiology of the body and address the greatest clinical challenges of our time, including the contemporary epidemic of autoimmune disorders.

This book describes statistical concepts and techniques for evaluating medical diagnostic tests and biomarkers for detecting disease. More generally, the techniques pertain to the statistical classification problem for predicting a dichotomous outcome. Measures for quantifying test accuracy are described including sensitivity, specificity, predictive values, diagnostic likelihood ratios and the Receiver Operating Characteristic Curve that is commonly used for continuous and ordinal valued tests. Statistical procedures are presented for estimating and comparing them. Regression frameworks for assessing factors that influence test accuracy and for comparing tests while adjusting for such factors are presented. This book presents many worked examples of real data and should be of interest to practicing statisticians or quantitative researchers involved in the development of tests for classification or prediction in medicine.