Acute myeloid leukemia (AML) is an aggressive bone marrow cancer associated with high morbidity and mortality and most commonly affects older patient populations. In this book, the clinical presentation of acute myeloid leukemia are presented. Other chapters present the differences in the outcomes of two subtypes of core binding factor (CBF) acute myeloid leukemia (AML); examine the occurrence of the Philadelphia chromosome in AML with core binding factor leukemia; and therapeutic options of older patients with AML.

Delirium is an acute change in mental status, which has the features of a fluctuating mental status, inattention, and either disorganised thinking or altered level of consciousness. It is a common development particularly in hospitalised elderly patients. Delirium is independently associated with adverse sequelae including increased mortality, institutionalisation and cognitive decline. Despite this, case identification remains poor, with up to two-thirds being missed or mis-attributed to dementia, depression and other neuropsychiatric diagnoses. This book discusses how delirium affects the critically ill; early detection of delirium; delirium in surgical patients; and delirium's connection to eating disorders.

Now in a greatly expanded and updated new edition: The essential pocketbook for rapid and correct differentiation and interpretation of signs and symptoms of neurological and neurosurgical diseases and conditions. Key Features: Exhaustive range of neurologic and neurosurgical disease and conditions covered Vital information presented in short texts, high-yield lists, and concise tables, for maximum efficiency in diagnostic work-ups Clinical and neuroimaging findings, guidelines and classifications, summarized in readily accessible tabular form Statistic overviews (common vs. rare, etc.) help guide diagnostic thought processes Special chapters highlight epidemiology, pediatric disorders, neuroradiology Differential Diagnosis in Neurology and Neurosurgery is ideal as a quick reference in your daily practice, or as an exam preparation guide. This wealth of easily accessed information makes it invaluable to experienced practitioners (especially ER physicians) and to novices alike. This book includes complimentary access to a digital copy on https://medone.thieme.com.

Predictive, preventive and personalised medicine offers great promise for the future practice of medicine. Essential components of this approach include well-organised population screening protocols utilising novel diagnostic biomarkers of disease states, targeted prevention of common human pathologies, optimal treatment planning and personalised medicine thereby resulting in substantial improvement of the quality of life. This approach also offers the advantage of delivering care at potentially reduced costs to the population at large thereby addressing social and ethical issues related to access to and affordability of health care. Consequently, conventional medicine and new branches of biomedicine are currently challenging many issue-related questions: Should molecular diagnostic approaches be considered complementary or substitutive measures to conventional approaches? How reliable are biomarkers for any given pathology? How to distinguish between the highly predictive power of innovation and quackery in diagnostics? How to overcome currently well-recognisable (inter)national barriers in knowledge transfer? How to correctly educate the new generation of experts in bio- and predictive medicine? The book addresses these highly relevant issues and provides some clues for plausible solutions. The information presented in this book emphasises the necessity of individualised patient treatment and provides compelling reasons as to why "across-the-board" treatment is not warranted. Application of nutritional proteomics results in individualised optimal diet and may potentially restrict the epidemic scale of type 2 Diabetes mellitus. A broad distribution and a routine clinical utilisation of these advanced technological approaches could enable a significant portion of the population to reach the 100-year age limit yet remaining vibrant in excellent physical and mental health and as actively contributing members of society. The examples given in the book are based on well-recognised expertise, scientific publications and international patents. A panel of leading world experts and authorities of the international issue-related associations have contributed to the book by addressing relevant issues and topics such as model-based patient-care and individualised therapy-planning, reproductive medicine and postnatal diagnostics, early/predictive diagnosis and optimised treatment of cancer as well as the most frequent neurodegenerative disorders.

Look no further for quick, complete answers to questions such as which laboratory tests to order or what the results might mean. Laboratory Tests And Diagnostic Procedures, 5th Edition covers more tests than any other reference of its kind, with over 900 lab tests and diagnostic procedures in all. In Part I, you'll find a unique, alphabetical list of hundreds of diseases, conditions, and symptoms, including the tests and procedures most commonly used to confirm or rule out a suspected diagnosis. Part II presents key information on virtually every laboratory and diagnostic test available. All test entries are up-to-date, concise, complete, and consistently presented, making this resource the perfect choice for students or practitioners who need fast, accurate information on diagnostic tests. More than 900 laboratory tests and diagnostic procedures are included - more than any other reference! Over 600 diseases, conditions, and symptoms are listed, along with the tests used to confirm them. Alphabetical organization and A-to-Z thumb tabs make it easy to find the information you're looking for. Alternative test names and acronyms are cross-referenced to simplify lookup. Instructions for client and family teaching help you offer guidance concerning test preparation and follow-up care. Age and gender-specific norms are provided, giving you complete lifespan coverage. Risks and Contraindications are highlighted to help you safeguard your patients and provide effective care. Panic Level Symptoms and Treatment are provided for dangerously increased and decreased levels. Minimum volumes for blood samples are included, useful when a client's blood preservation is essential, as well as information on whether blood specimens can be drawn during hemodialysis. Tests for toxic substances are included, making this a lab, diagnostic, and toxicology book all in one. Abbreviations, measurement prefixes, and symbols are listed on the front and back covers for convenience. Information on herbal supplements indicates when a client's use of natural remedies might affect test results. Over 20 NEW test entries present the latest tests and procedures, with a strong focus on affordable, clinically relevant genetic tests. UPDATED content includes the latest research relating to accuracy of tests, diagnostic value of results, and associated cost-benefit ratios.

A Davis’s Notes book! This pocket-sized reference provides great information on phlebotomy techniques, with nice summaries of procedures with many photos and illustrations. It is ideal for clinical rotations, for quick review of coursework, and to study in preparation for your certification exam. The write-on/wipe-off pages feature a dedicated space where you can fill in the specific requirements for evacuated tubes, instrumentation, and analytical procedures for two different locations. Clinically focused, it’s the perfect guide to collecting, transporting, and processing quality blood specimens for laboratory testing. Essential Pocket Guide for Phlebotomy! "It has a lot of information, with step-by-step instructions with pictures. This is essential if you will be doing any phlebotomy of any kind." - Pamela O., Amazon Reviewer Great resource. "Love this book! While doing my externship this book was recommended to me. I am very glad that I ordered it. It includes labs and the corresponding tube colors which is something I needed. It is wipeable and will fit in the pocket of my scrubs. I have already recommended it to the other students who were in class with me." - T.S, Amazon Reviewer Phlebotomist Must Have! "These Phlebotomy Notes were very helpful overviewing all key notes for my Exam and while doing my Clinicals, very easy to navigate. Will continue to use it through my Career in Phlebotomy." - Cali, Amazon Reviewer

Medical Response to Adult Sexual Assault, Second Edition provides evidence-based research on diagnosis, treatment, and examination in cases of sexual violence and assault. Survivors of sexual assault face any number of unique challenges both on the path to physical and psychological recovery and in navigating the investigative and judicial processes related to their traumatic experiences. Medical practitioners who work with these survivors require informed expertise in order to support their patients' safety and personal well-being. The authors and contributors, a team of expert physicians, nurses, attorneys, and other multidisciplinary practitioners, have fully revised and updated Medical Response to Child Sexual Abuse to reflect contemporary best practices in the investigation and treatment of sexual violence. Any professionals who work with victims of sexual assault will find this latest edition essential to their responsibilities and to the renewed well-being of those in their care.

2017 Choice Outstanding Academic Title With over forty years of experience as a sought after diagnostician, Dr. Stuart Mushlin has cracked his share of medical mysteries, ones in which there are bigger gambles than playing the ponies at the track. Some of his patients show up with puzzling symptoms, calling for savvy medical detective work. Others seem to present cut-and-dry cases, but they turn out to be suffering from rare or serious conditions.   In Playing the Ponies and Other Medical Mysteries Solved, Dr. Mushlin shares some of the most intriguing cases he has encountered, revealing the twists and turns of each patient’s diagnosis and treatment process. Along the way, he imparts the secrets to his success as a medical detective—not specialized high-tech equipment, but time-honored techniques like closely observing, touching, and listening to patients. He also candidly describes cases where he got things wrong, providing readers with honest insights into both the joys and dilemmas of his job.      Dr. Mushlin does not just treat diseases; he treats people. And this is not just a book about the ailments he diagnosed; it is also about the scared, uncertain, ailing individuals he helped in the process. Filled with real-life medical stories you’ll have to read to believe, Playing the Ponies is both a suspenseful page-turner and a heartfelt reflection on a life spent caring for patients. 

Neurology: A Clinician's Approach teaches a symptom-oriented approach to the 20 most common problems which face neurologists in training. Emphasizing the primary importance of the patient history, the reader is instructed which questions to ask in order to elicit the chief complaint, how to ask these questions, and how to interpret the answers. The neurologic examination is presented as a flexible diagnostic tool rather than as a rigid exercise to be performed by rote and without reference to the chief complaint. Each chapter integrates evidence-based and experience-based approaches to diagnostic testing and treatment. Frequently-encountered conditions, uncommon 'zebras', and non-neurologic mimics of nervous system dysfunction are all given appropriate weight. Neurology: A Clinician's Approach is essential reading for neurologists in training, including neurology residents and medical students.

The third updated and revised edition of Differential Diagnosis in Conventional Radiology provides essential information to make conventional x-ray an effective tool in diagnosing disorders affecting the bones and joints and the thoracic and abdominal body segments. The book is organized according to classifications of radiologic findings rather than disease, enabling the reader to approach diagnosis in a way that reflects the actual clinical situation. Concise and comprehensive tables outline key information on diagnosis and differential diagnosis. Highlights: The unique organization of chapters based on radiologic findings mirrors the situations encountered in daily clinical practice Easy-to-reference tables classifying findings, diagnosis, and differential diagnosis and providing important clinical data are perfect for an at-a-glance review More than 2000 radiographs and schematic diagrams help to guide the reader toward the most likely diagnoses The third edition of Differential Diagnosis in Conventional Radiology contains an updated and revised section on radiology of the abdomen combined with the complete text from the recently published books Bone and Joint Disorders and The Chest X-Ray by the same authors. An exceptional reference work to have on hand, Differential Diagnosis in Conventional Radiology will benefit radiologists and specialists seeking to improve their skills in diagnostic imaging and will also be of great interest to residents preparing for their specialist examinations.

A practical approach to the early detection and management of breast cancer This atlas provides radiologists with essential information for the differential diagnosis of breast diseases on the basis of clinical presentation, mammography, and ultrasound. It begins with chapters on tumor biology, prognostic factors, and histology. The authors then provide a thorough evaluation of various methods for early detection and accurate diagnosis, including analog and digital mammography, ultrasound, MR imaging, PET/CT, and interventional procedures. They discuss in detail the strengths and limitations of each imaging modality, aspects of quality control, test intervals, peri- and postoperative management principles, and follow-up care. Highlights: Presentation of difficult cases that effectively demonstrate the diagnostic hurdles and forensic pitfalls in breast diagnosis Special sections on breast cancer in men and young women, with discussion of women who are pregnant or lactating Color-coded practical tips and clinical notes for optimal comprehension of the material Extensive Q&A sections for self-testing in two major chapters More than 1,700 high-quality illustrations, including clinical color photographs, ultrasound images, and mammograms

Widely regarded as a standard clinical resource, this book helps practitioners think outside the mental health box and recognize when a client may need a medical evaluation. Part I provides an accessible overview of symptoms that can be observed in a standard mental status examination and may point to medical illness. Engaging case vignettes and interviewing pointers help readers hone their diagnostic skills. Part II presents concise facts--including basic medical information and physical and mental symptoms--on more than 60 diseases and syndromes. An easy-to-read chart in Part III cross-tabulates all of the disorders and symptoms for quick reference and comparison. New to This Edition *Reflects more than 15 years of advances in medical and mental health knowledge. *Updated throughout for DSM-5. *Additional medical disorders: celiac disease, traumatic brain injury, heavy-metal toxicity, and others. *Updated links to further reading on each health condition. Winner (First Place)--American Journal of Nursing Book of the Year Award, Psychiatric and Mental Health Nursing Category

Circulating cell-free DNA is poised to transform cancer diagnosis and care; however, it carries technical challenges such as low abundance, fragmentation and sensitivity to biospecimen handling. Development of clinically useful assays hinges on understanding the unique technical aspects of working with cell-free DNA as a substrate. This book provides an in-depth summary of the technical issues impacting cell-free DNA purification from blood plasma and analysis in a cancer context, including design of PCR assays, sequencing library preparation and methylation analysis. Emerging fields such as extracellular vesicles and blood nucleases are also covered, as well as basic biology and considerations pertinent to biobanking.

This eight-year study of an American city traces the answer to the question "Who is retarded?" by analyzing the labeling process in a large number of community agencies. Data for the study are drawn from a representative sample of 7,000 persons under fifty years of age who were tested ans screened for "symptoms" of mental retardation. The author finds that that schools label more persons as mentally retarded than any other agency and share their labels more widely with others in the community. Relying on IQ test scores for diagnosis, schools place many persons with scores above 70 and with no physical disabilities in the role of retardate. The author contends that both the statistical model of "normal" and the unicultural viewpoint of educators and clinicians work to the disadvantage of the poor and the ethnic minorities. Given the opportunity, many persons demonstrate by their ability to cope with the problems in other areas of life that they are not comprehensively incompetent. The author makes serval policy recommendations. First, she suggests lowering the IQ score cutoff point used by schools in determining who shall be labeled as retarded. Second, she recommends that the clinicians use the two-dimensional definition of retardation proposed by the American Association of Mental Deficiency, subnormality in both intellectual performance and adaptive behavior. Third, she concludes that pluralistic assessment procedures must be employed to take into account cultural biases in IQ tests designed to measure cognitive skills. This title is part of UC Press's Voices Revived program, which commemorates University of California Press's mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1973.