A didactic, illustrated guide to the use of ultrasound as a diagnostic tool in clinical practice. Prepared by an international group of experts with wide experience in both developed and developing countries, the manual responds to the need for a basic reference text that can help doctors, sonographers, nurses, and midwives solve imaging problems when no experts are available. With this need in mind, the manual adopts a practical approach aimed at providing a thorough grounding in both the techniques of ultrasound and the interpretation of images. The need for extensive supervised training is repeatedly emphasized. Because the clinical value of ultrasound depends so greatly on the experience and skill of the operator, the manual makes a special effort to alert readers to common pitfalls and errors, and to indicate specific clinical situations where ultrasound may not be helpful or reliable as a diagnostic tool. Explanatory text is supported by numerous practical tips, warnings, checklists and over 600 illustrations. The opening chapters explain how ultrasound works, outline the factors to consider when choosing a scanner, and introduce the basic rules of scanning, including advice on how to recognize and interpret artefacts. Guidance on the selection of ultrasound equipment includes clear advice concerning where costs can be spared and where investment is essential. The core of the manual consists of seventeen chapters providing guidance on scanning techniques and the interpretation of images for specific organs and anatomical sites, with the most extensive chapter devoted to obstetrics. Each chapter contains illustrated information on indications for scanning, preparation of the patient, including choice of transducer and setting of the correct gain, general scanning techniques, and specific techniques for identifying anatomical landmarks and recognizing abnormalities. The manual concludes with WHO specifications for a general-purpose scanner judged entirely suitable for 90-95% of the most common ultrasound examinations.

Differential Diagnosis of Neuromusculoskeletal Disorders is a pocket-sized handbook designed to provide the chiropractic physician, intern, and student with a quick reference manual for differential diagnosis. The topics covered encompass most of the syndromes seen in everyday chiropractic cases involving neurology, orthopaedics, and diagnostic imaging.

The transformation from medical student to physician is a gradual one, requiring the assimilation of vast amounts of knowledge as well as the development of the ability to "think like a doctor." The thought processes that enable a physician to "think like a doctor" are perhaps the most difficult skills the clinician-in-training must acquire in medical school and residency. In this extraordinary book, Dr. Howard Barrows, one of the world's foremost medical educators, beautifully and simply articulates those mental processes that allow accomplished physicians to reach diagnostic conclusions with speed and confidence. Students who master the contents of this book will take a long step forward in acquiring the diagnostic skills that are the hallmark of the experienced physician.

Students starting on the wards are often bewildered at their role and unable to make the most of the learning opportunities presented to them. The hardest thing is to adapt to a new way of learning, where books and lectures take a back seat and the subjects for study are the patients whose beds line the wards. Rather than being asked to go to the library and write an essay on the physiology of the kidneys, you are told to go and clerk the patient in bed 3 with acute renal failure. The problem lies in knowing where on earth to begin.
Clinical Medicine: A Clerking Companion is written for inexperienced clinical students, and helps them to use their patients to learn medicine. It aims to transform students who know a bit about the medical sciences into young doctors who can draw knowledge and experience together to diagnose and treat real patients.
At heart, it is a workbook that provides students with a framework for approaching patients with a range of common conditions. It is a 'friend over the shoulder' - guiding students through interviewing and examining a patient, and then evaluating the patient's current condition and their future management. A list of questions then helps students explore the topic in more detail - sending them back to their textbooks to read about what they have seen and understand the science underlying it.
It is also a self-directed learning portfolio, helping students to assess their progress by seeing where they are lacking clinical exposure, and by recording key cases they have seen to function as a revision aid.
Clinical Medicine: A Clerking Companion falls into three main sections.
The introduction explains briefly how to use the book to make the most of time spent on the wards - how to interview and examine patients, how to use the book in recording findings, and then how to present patients to doctors. It emphasises the importance of anonymising patient information and ensuring patient consent before interviewing and examining them.
The section on presentations covers over 30 undiagnosed presenting complaints such as 'chest pain' or 'acute confusion', suitable for use in A+E or in outpatient. Proformas for each presentation take students through the dynamic process of diagnosis and initial management.
The largest section, conditions, covers around 100 common medical and surgical problems, grouped according to speciality. Each chapter (for instance 'cardiology') begins with an introductory section offering basic approaches to the symptoms, signs and investigations encountered in that specialty - for instance, how to recognise common murmurs or a simple guide to reading an ECG. The subsequent clerking proformas are similar to those for the clinical 'presentations', allowing students to interview and examine ward patients who already have an established diagnosis, reviewing their investigation results, and then evaluating the severity, aetiology and management of the condition.
The book aims to:
DT Transform patients into useful learning resources: helping students to use patients to develop skills and build knowledge.
DT Be a 'near patient resource': something to be carried onto the ward and used when seeing patients.
DT Enable students to be pro-active: Lots of time can be wasted as a medical student waiting for doctors to be free to teach you. This allows even very junior students to get on with clerking and evaluating patients.
DT Build student confidence: Presenting patients you have clerked to senior doctors can be daunting. With this book students can do so more confidently knowing that they have at least covered all the more important points.
DT Train students to think clinically: So much of medical education involves teaching a mindset - actively resuscitating a patient whilst also trying to diagnose them, or weighing the relative importance of various pieces of information. Other books present information - this book teaches students to use it.
A completely new concept, with a unique focus on the learning needs of inexperienced students, Clinical Medicine: A Clerking Companion is the one friend you won't want to be without as you begin your journey onto the wards.
Online Resource Centre
The Online Resource Centre to accompany Clinical Medicine: A Clerking Companion features:
DT Dynamic, annotated figures - enlarged, fully annotated copies of key images from the book, including ECGs and X-rays.
DT PDFs of the proformas in the book, avalible to download

Since 1980, Dr. Osborn's An Introduction to Cerebral Angiography has been "the" definitive text on this imaging modality. Now, this classic work has been completely revised, reorganized, and updated and expanded from an introductory book into a comprehensive, state-of-the-art reference on cerebral angiography.Diagnostic Cerebral Angiography, Second Edition, is organized into three major parts. Part 1 covers techniques and technical aspects of cerebral angiography. Part 2 is a detailed description of normal anatomy, anatomic variations, and congenital anomalies. Part 3 focuses on pathological entities, including trauma, aneurysms, stroke, vascular malformations, atherosclerosis, and vasculitis.Coverage includes new information on vascular territories, film subtraction, and magnetic resonance angiography. The text is thoroughly illustrated with 1,200 radiographs and line drawings, all of them new to this volume. Another new feature of this Second Edition is the use of boxed summaries throughout the text to highlight key points.

Now in a greatly expanded and updated new edition: The essential pocketbook for rapid and correct differentiation and interpretation of signs and symptoms of neurological and neurosurgical diseases and conditions. Key Features: Exhaustive range of neurologic and neurosurgical disease and conditions covered Vital information presented in short texts, high-yield lists, and concise tables, for maximum efficiency in diagnostic work-ups Clinical and neuroimaging findings, guidelines and classifications, summarized in readily accessible tabular form Statistic overviews (common vs. rare, etc.) help guide diagnostic thought processes Special chapters highlight epidemiology, pediatric disorders, neuroradiology Differential Diagnosis in Neurology and Neurosurgery is ideal as a quick reference in your daily practice, or as an exam preparation guide. This wealth of easily accessed information makes it invaluable to experienced practitioners (especially ER physicians) and to novices alike. This book includes complimentary access to a digital copy on https://medone.thieme.com.

The diagnosis and monitoring of hematological malignancies is complex and requires a systematic approach. Morphology, cell phenotyping, cytogenetics and molecular genetics are essential, and the results must be integrated. Diagnostic Techniques in Hematological Malignancies details the principles and applications of each of these test types in the diagnosis of hematological malignancies in blood and bone marrow. The first section describes the test modalities - including methodological principles, data interpretation and limitations - and is illustrated by clinical examples. The second section focuses on the clinical entities, detailing the most appropriate tests for diagnosis, staging and monitoring of different hematological malignancies and includes test utilization to identify prognostic markers and potential therapeutic targets. With contributions from multiple international experts, this illustrated book is an essential resource for qualified and trainee hematologists, oncologists, and pathologists. It's a practical and useful guide, providing a rational and structured approach to the laboratory assessment of hematological malignancies.

The opening chapter of The Essential Guide to Magnetic Resonance presents applications of Fluorine-19 Magnetic Resonance Imaging (19F MRI) in cancer research, tissue metabolomics, quantification of drug delivery, cellular tracking, tissue pH measurements and detection of 19F labeled cells. The authors review in vitro research applying 19F MRI and Magnetic Resonance Spectroscopy (MRS) to facilitate the synthesis, tracking and visualization of new fluorinated drug conjugates. 19F MRI also provides high contrast in vivo images due to the absence of an endogenous 19F signal, 100% natural abundance of 19F, and a chemical shift range of over 400 ppm. Afterwards, examples of current methods of magnetic resonance imaging (MRI) guided photodynamic therapy are presented. Recent development of MRI detectable nanoparticle constructs, magnetic resonance spectroscopy (MRS) sensors, gadolinium based photosensitizers and europium singlet oxygen probes are discussed. In addition, applications of Functional MRI using a blood oxygen dependent level (BOLD) MRI in monitoring photodynamic action are addressed, with the goal of informing researchers about the potential for using MRI guided photodynamic therapy and oxygen dosimetry. The applications of MRI within the sphere of pharmacy are analyzed; in particular, the use of MRI to track pharmaceuticals in vitro and in vivo noninvasively and monitoring their controlled-release. Functional MRI for noninvasive clinical brain imaging is explored as it is applied to studies of autism, schizophrenia, epilepsy Alzheimers disease, Parkinson's disease, traumatic brain injury and blood oxygenation-level dependent (BOLD) imaging of brain function. An overview of the scope of MRI as a diagnostic technique in neurology and in neurosurgery is also provided.

The knowledge of the morphofunctional features from the coronary microcirculation is essential for understanding its role in cardiac physiological work and in the pathogenesis of coronary microvascular dysfunction (CMD). The cardiovascular system comprises the heart and blood vessels, including arteries, veins, and capillaries, both systemic and pulmonary. Arterioles are the primary site of vascular resistance and have only one to two layers of smooth muscular walls. Chapter One will provide an overview of the coronary microcirculation, its functions and regulatory mechanisms. The importance of CMD will be summarised in the context of diverse clinic scenarios, considering its pathogenesis, assessment and therapeutic management. The purpose of Chapter Two is to understand the role of arteriolar endothelial dysfunction in CVDs and its underlying mechanisms. Chapter Three will explore the physiopathology, epidemiology, and the diagnosis and treatment of hypertensive retinopathy. Chapter Four reports on angiogenesis, a critical process for reproduction in mammals, which consists of arterioles and blood vessels formation from the existing ones.

This book is written for the primary care clinician to help update knowledge of pediatric endocrinology (with an emphasis on diabetes) from both ancient and modern times. The current and future shortage of pediatric endocrinologists necessitates steady, rejuvenated information on diabetes and other endocrine disorders for primary care clinicians as they care for the child and adolescent with complex endocrine dilemmas and disorders. In view of this shortage and the rapidly increasing knowledge in pediatric diabetes as well as understanding indications for referral to pediatric endocrinologists in the 21st century, au courant assiduous information aimed at primary care clinicians in these areas becomes increasingly important.

Chronic Lymphocytic Leukemia (CLL) is the most common leukemia in the western world, seen mostly in the elderly age-group and has a very variable clinical outcome. Traditionally considered an indolent, antigen inexperienced leukemia of slowly accumulating cells that do not die, researchers now acknowledge that CLL cells are highly proliferative, antigen experienced cells that have a high cell turnover and a subset show an aggressive clinical course. The onset of the disease is usually asymptomatic; only abnormalities in whole blood count such as leukocytosis with lymphocytosis are found. Nowadays, CLL is diagnosed more often at an early, asymptomatic stage due to more frequent routine blood tests. More advanced stages are characterized by lymphadenopathy, hepatomegaly/splenomegaly, recurrent infections, weakness, pallor and hemorrhagic diathesis, and general symptoms such as weight loss, fever and night sweats are observed. This book reviews the diagnosis, treatment options and prognosis of CLL.

Psoriasis is a common, non-infectious, chronic inflammatory skin disease characterised by distinctive erythematous plaques that multiply and scale over with silvery patches. Psoriasis can affect any cutaneous site and is frequently found on the extensor skin surface of elbows and knees, scalp and sacral regions. Psoriasis is also associated with systemic conditions, including psoriatic arthritis, Crohns disease and lymphoma. This book discusses the epidemiology, diagnosis and management strategies of psoriasis. Chapter One provides an overview of the challenging medical condition. Chapter Two discusses the possible factors raised by literature as main contributors to sleep disturbances and its correlation to psoriasis. Chapter Three gives an overview of the current results where blood plasma thermal changes have been detected by Differential Scanning Calorimetry (DSC) technique on psoriatic patients with different clinical stages, and monitored patients with no symptoms to patients with serious symptoms. Chapter Four discusses psoriasis treatment that targets the IL-23/Th17 axis. Chapter Five reviews natural health products for managing psoriasis.

This book discusses the diagnosis, treatment and management of liver disease. Chapter One reviews hepatic hydatidosis. Chapter Two explores the diagnosis, natural history, and management for patients with chronic hepatitis C (CHC). Chapter Three discusses scientific evidence that explains the relationship between metabolic syndrome, non- alcoholic fatty liver disease (NAFLD) and psoriasis and the treatment strategy for this co-morbid condition. Chapter Four examines the pathophysiology and treatment of liver cirrhosis. Chapter Five reviews surgical strategies to push up resection limits in liver disease and liver failure after surgery.

Acute myeloid leukemia (AML) is an aggressive bone marrow cancer associated with high morbidity and mortality and most commonly affects older patient populations. In this book, the clinical presentation of acute myeloid leukemia are presented. Other chapters present the differences in the outcomes of two subtypes of core binding factor (CBF) acute myeloid leukemia (AML); examine the occurrence of the Philadelphia chromosome in AML with core binding factor leukemia; and therapeutic options of older patients with AML.

Video Protocols and Techniques for Movement Disorders presents this visually-based subspecialty through a truly unique product, illustrating how to establish a start-of-the-art videotaping workspace as well as how to instruct patients on how to participate in videotaped examination. The authors cover various technical issues-space, lighting, equipment-as well as medical protocols related to filming movement disorders, accounting for patient variability and abilities. This essential guide teaches the reader how to capture the key features of a given patient's disorder, detailing the ideal interactions between the videographer and patient. Issues of video storage and editing are addressed in practical terms. Your purchase of Video Protocols and Techniques for Movement Disorders provides you personal access to this online-only product as part of Oxford Medicine Online (www.oxfordmedicine.com http://www.oxfordmedicine.com). At the time of this printing, Oxford Medicine Online allows you to print, save, cite, email, and share content; download high-resolution figures as PowerPoint (R) slides; save often-used books, chapters, or searches; annotate; and quickly jump to other chapters or related material on a mobile-optimized platform. Oxford Medicine Online's applicable Privacy Policy and Legal Notice (available at www.oxfordmedicine.com) shall govern your use of the site. Technical Requirements In order to access Video Protocols and Techniques for Movement Disorders as part of the Oxford Medicine Online website, you need a standard web browser such as: Internet Explorer 9; Mozilla Firefox 9; Safari 5; Google Chrome 17 or 18. You will also need an internet connection, HTML and JavaScript support. Your operating system should be one of the following: Windows XP; Windows Vista; Windows 7; MAC OSX+. You will also need MS Office installed on your computer to be able to open images in PowerPoint files. The Oxford Medicine Online products are best viewed with a screen resolution of 1024x768, although they will also work at higher and lower resolutions. Please note that some tables are wide and so require 1024x768 screen resolution.

Hearing the patient's story, asking the right questions, and doing a careful, thorough and informed physical examination are intrinsic to good medicine. It is easy to rely and become dependent on technology to diagnose and to treat our patients. Yet, no machine will ever be a match for a listening ear and the laying on of hands. These skills are core to the art of medicine and require practice. It is only by becoming familiar with the norm that we can appreciate the norm. This book is a clinical skills textbook with a third dimension -- the human factor. We read about real people, real symptoms and real diagnostic problems. It doesn't waste time on rare physical signs that will never be encountered but instead, focuses on common, important clinical skills and symptom patterns.

Predictive, preventive and personalised medicine offers great promise for the future practice of medicine. Essential components of this approach include well-organised population screening protocols utilising novel diagnostic biomarkers of disease states, targeted prevention of common human pathologies, optimal treatment planning and personalised medicine thereby resulting in substantial improvement of the quality of life. This approach also offers the advantage of delivering care at potentially reduced costs to the population at large thereby addressing social and ethical issues related to access to and affordability of health care. Consequently, conventional medicine and new branches of biomedicine are currently challenging many issue-related questions: Should molecular diagnostic approaches be considered complementary or substitutive measures to conventional approaches? How reliable are biomarkers for any given pathology? How to distinguish between the highly predictive power of innovation and quackery in diagnostics? How to overcome currently well-recognisable (inter)national barriers in knowledge transfer? How to correctly educate the new generation of experts in bio- and predictive medicine? The book addresses these highly relevant issues and provides some clues for plausible solutions. The information presented in this book emphasises the necessity of individualised patient treatment and provides compelling reasons as to why "across-the-board" treatment is not warranted. Application of nutritional proteomics results in individualised optimal diet and may potentially restrict the epidemic scale of type 2 Diabetes mellitus. A broad distribution and a routine clinical utilisation of these advanced technological approaches could enable a significant portion of the population to reach the 100-year age limit yet remaining vibrant in excellent physical and mental health and as actively contributing members of society. The examples given in the book are based on well-recognised expertise, scientific publications and international patents. A panel of leading world experts and authorities of the international issue-related associations have contributed to the book by addressing relevant issues and topics such as model-based patient-care and individualised therapy-planning, reproductive medicine and postnatal diagnostics, early/predictive diagnosis and optimised treatment of cancer as well as the most frequent neurodegenerative disorders.

Thousands of high-quality clinical photographs paired with authoritative clinical content make Zitelli and Davis' Atlas of Pediatric Physical Diagnosis the trusted, go-to resource for residents and physicians alike. In this thoroughly revised 8th Edition, Drs. Basil J. Zitelli, Sara C. McIntire, Andrew J. Nowalk, and Jessica Garrison, provide a much-needed visual perspective on pediatric illness, helping you hone your visual examination skills and improve your diagnostic accuracy. Features more than 3,000 color photographs supplemented by clear explanatory text, laboratory tests, tables, algorithms, imaging, and approximately 25 clinical videos. Emphasizes pertinent historical factors, examination techniques, visual findings, and diagnostic methods. Provides meticulously updated content throughout, including an extensively revised ophthalmology chapter. Discusses key topics in pediatrics such as development, child abuse, and adolescent gynecology. Covers both common and uncommon disorders, making it an excellent resource not only for clinical diagnosis, but also for studying for the pediatric boards. Lists actionable and practical references, bibliographies, and resources at the end of each chapter. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Precision medicine is a topical subject that attracts tremendous attention from scientific and medical communities, being set to transform health care in the future. This book will be among the first to cover the detection methods for precision medicine. The first section provides an overview of the biomarkers used for precision medicine, such as proteins, nucleic acids, and metabolites. The coverage then turns to sequencing techniques and their applications, and other bioanalytical techniques, including mass spectrometry for proteome and phosphoproteome analysis, immunological methods and droplet technologies. The final sections include biosensors applied to precision medicine and clinical applications. This book provides a reference for researchers and students interested and working in the development of bioanalytical techniques for clinical applications. It provides a useful introduction for physicians and medical laboratory technologists to the recent advances in detection methods for precision medicine.

A comprehensive, systematic approach to 12-lead EKG interpretation covering all relevant topics you'll encounter in clinical practice including treatment options!Delivering clear and concise explanations to help students easily grasp key concepts, this book provides a comprehensive, no-nonsense approach to EKG interpretation for nurse practitioner and physician assistant students, as well as practicing clinicians who need a quick refresher. The third edition retains the book&'s systematic, physiologic approach that trains readers to follow the same steps in evaluating EKG tracings. After working through this book, you'll gain a genuine understanding of EKG interpretation and will no longer need to memorize EKG strips. Using the patient's presenting symptoms as a starting point, abundant clinical scenarios demonstrate real-life applications for interpreting EKG readings. With over 75 figures and tables and more than 260 EKG tracings, this resource delivers everything you need to provide expert, quality care to your patients. NEW to the THIRD EDITIONn Treatment options included for premature atrial and ventricular contractions, atrial and ventricular arrhythmias, ischemia and infarction, and heart block 14 in-depth chapter case scenarios to further challenge you and increase your proficiency in EKG interpretation 60 new EKG tracings, providing you with more than 260 tracings throughout the book Evidence-based approaches to differentiate between similar EKG patterns New high-risk EKG descriptions, including multiple types of high-grade heart block and Wellen's syndrome for acute myocardial infarction Risk stratification techniques for heart block, acute coronary syndromes, and supraventricular and ventricular arrhythmias utilizing the EKG KEY FEATURES Addresses EKG interpretation using a systematic, physiologic approach, eliminating the need for memorization Uses the patient's presenting clinical symptoms as a starting point to teach critical thinking Includes more than 75 figures and tables and 260 EKG tracings to further illustrate concepts Offers 140 end-of-chapter review questions to help solidify your knowledge Includes 70 case studies with EKG tracings and teaching points at the end of the book, plus additional case studies in each chapter, to connect key concepts with real-world learning

Medical Response to Adult Sexual Assault, Second Edition provides evidence-based research on diagnosis, treatment, and examination in cases of sexual violence and assault. Survivors of sexual assault face any number of unique challenges both on the path to physical and psychological recovery and in navigating the investigative and judicial processes related to their traumatic experiences. Medical practitioners who work with these survivors require informed expertise in order to support their patients' safety and personal well-being. The authors and contributors, a team of expert physicians, nurses, attorneys, and other multidisciplinary practitioners, have fully revised and updated Medical Response to Child Sexual Abuse to reflect contemporary best practices in the investigation and treatment of sexual violence. Any professionals who work with victims of sexual assault will find this latest edition essential to their responsibilities and to the renewed well-being of those in their care.

Best of Five MCQs for the MRCP Part 1 volumes 1-3 offers a comprehensive and trustworthy solution to anybody wishing to sit, pass and excel at the Membership of the Royal College of Physicians Part 1 examination. Presented as a unique three-volume set, each volume features 375 high-quality practice questions on each of the systems and specialties in alphabetical order. Volume 2 features Best of Five questions on dermatology, endocrinology, gastroenterology, geriatric medicine, infectious diseases, and ophthalmology. All 375 questions contain questions written and reviewed by successful candidates and previous examiners, and are accompanied by detailed explanations and further reading, ensuring complete and successful revision for this challenging exam. Matched to the latest Royal College curricula in coverage and format, this dedicated resource provides readers with an accurate, authoritative and evidence-based companion to the MRCP Part 1.

2017 Choice Outstanding Academic Title With over forty years of experience as a sought after diagnostician, Dr. Stuart Mushlin has cracked his share of medical mysteries, ones in which there are bigger gambles than playing the ponies at the track. Some of his patients show up with puzzling symptoms, calling for savvy medical detective work. Others seem to present cut-and-dry cases, but they turn out to be suffering from rare or serious conditions.   In Playing the Ponies and Other Medical Mysteries Solved, Dr. Mushlin shares some of the most intriguing cases he has encountered, revealing the twists and turns of each patient’s diagnosis and treatment process. Along the way, he imparts the secrets to his success as a medical detective—not specialized high-tech equipment, but time-honored techniques like closely observing, touching, and listening to patients. He also candidly describes cases where he got things wrong, providing readers with honest insights into both the joys and dilemmas of his job.      Dr. Mushlin does not just treat diseases; he treats people. And this is not just a book about the ailments he diagnosed; it is also about the scared, uncertain, ailing individuals he helped in the process. Filled with real-life medical stories you’ll have to read to believe, Playing the Ponies is both a suspenseful page-turner and a heartfelt reflection on a life spent caring for patients.