This book highlights both conventional and nanomaterials-based biosensors for the detection of cervical cancers. It describes developments in the selective and sensitive electrochemical biosensors based on DNA for the early diagnosis of cervical cancer. Further, this book covers other nano-biosensing systems such as nano-thermometry-based sensing platforms, mechanical sensing platforms encompassing piezoelectric-based sensors, electrochemical impedance spectroscopy based on PEGylated arginine functionalized magnetic nanoparticles, and field-effect transistor-based platforms for the early detection of cervical cancer. Also, it presents conventional platforms such as vibrational spectroscopy and polymerase chain reaction techniques for the diagnosis of cervical cancer. Finally, it reviews currently available biomarkers for the early diagnosis of cervical cancer and presents strategies for developing novel biomarkers based on cellular and molecular approaches. As such, this book is a comprehensive resource for researchers and clinicians working in cervical cancer diagnostics.

This unique book provides a thorough overview of developing molecular cancer diagnostic assays, which are the prerequisites for optimal solutions within personalized cancer medicine. The book takes the reader through definitions of the pharmacodiagnostic concept, historical perspectives of the early steps into molecular cancer diagnostics linked to therapy, the basis of different diagnostic molecular techniques, ongoing research, drug-diagnostic co-development, assay validation, clinical trial methodology, regulatory issues around pharmacodiagnostics and future aspects within personalized cancer medicine.

Written specifically for urological trainees by a distinguished team of contributors, this third edition of The Scientific Basis of Urology provides the reader with a thorough coverage of urology. Every area, function, illness and treatment of the urinary tract, along with specific discussions of the relevant anatomy and physiology, is included in clearly written text, abundantly illustrated with full color photographs and diagrams. Each chapter takes the basic principles of its topic area and expands upon them to ensure maximum understanding.

Entirely new chapters in the Third Edition:

• Genetic and Biological Alterations in Cancer
• The Scientific Basis of Male Hypogonadism
• Minimally Invasive Technologies in the Treatment of Renal and Prostate Cancer
• Preoperative Assessment

Breathborne biomarkers carry information on the state of human health, and their role in aiding clinical diagnosis or in therapeutic monitoring has become increasingly important as advances in the field are made. Breathborne Biomarkers and the Human Volatilome, Second Edition, provides a comprehensive update and reworking of the 2013 book Volatile Biomarkers, by Anton Amann and David Smith. The new editing team has expanded this edition beyond volatile organic compounds to cover the broad field of breath analysis, including the many exciting developments that have occurred since the first edition was published. This thoroughly revised volume includes the latest discoveries and applications in breath research from the world's foremost scientists, and offers insights into related future developments. It is an ideal resource for researchers, scientists, and clinicians with an interest in breath analysis.

Combining the fundamental coverage of a traditional nursing assessment text with a modern, student-friendly presentation and an enhanced emphasis on clinical judgment, Nursing Health Assessment: A Clinical Judgment Approach, 4th Edition, helps students easily develop the understanding, critical thinking, and decision-making skills to excel in any clinical setting. A consistent, two-column format presents normal and abnormal findings and guides students progressively through realistic clinical case scenarios, instilling the nursing knowledge to observe and assess situations, prioritize patient concerns, and generate the best possible solutions. Case-based Next Generation NCLEX (R) (NGN) style questions throughout the text (and answers with rationales in an appendix) align with the NCSBN Clinical Judgment Model (NCJMM) to prepare students for success on the Next Generation NCLEX (R) and to help them confidently deliver safe patient care in any clinical setting. New and Updated Features for the 4th Edition NEW! 180 case-based Next Generation NCLEX (R) (NGN) style questions (and answers with rationales) boost students' exam readiness and test-taking confidence. NEW! NCSBN Clinical Judgment Measurement Model (NCJMM) cues, hypotheses, and evaluation components incorporated into case studies throughout the text strengthen students' critical thinking and decision-making capabilities. UPDATED! New and revised content familiarizes students with social determinants of health, incorporates unbiased language, and reflects current infection and source control measures. UPDATED! Diagnoses incorporate International Classification for Nursing Practice [INCP] language to clarify challenging terminology.

There are numerous advantages to using Bayesian methods in diagnostic medicine, which is why they are employed more and more today in clinical studies. Exploring Bayesian statistics at an introductory level, Bayesian Biostatistics and Diagnostic Medicine illustrates how to apply these methods to solve important problems in medicine and biology. After focusing on the wide range of areas where diagnostic medicine is used, the book introduces Bayesian statistics and the estimation of accuracy by sensitivity, specificity, and positive and negative predictive values for ordinal and continuous diagnostic measurements. The author then discusses patient covariate information and the statistical methods for estimating the agreement among observers. The book also explains the protocol review process for cancer clinical trials, how tumor responses are categorized, how to use WHO and RECIST criteria, and how Bayesian sequential methods are employed to monitor trials and estimate sample sizes. With many tables and figures, this book enables readers to conduct a Bayesian analysis for a large variety of interesting and practical biomedical problems.

Objective Structured Clinical Examinations (OSCEs) are commonly encountered at all levels of medical school including the final MBBS examination. OSCEs also play an important role at postgraduate level and are used to assess competency in the Foundation Years. One of the fundamental requirements of passing the OSCE is an understanding of the standard which is expected and an appreciation of how to demonstrate this. This book discusses 170 commonly encountered OSCE scenarios, with a step-by-step approach to maximise your chances of success in the examination. The scenarios are presented with sufficient background information to enable candidates to tackle variations. This comprehensive book, covering both surgery and medicine, overcomes any problems of a tick-box approach and insufficient detail faced by some alternative texts. The clear, straight-forward style and logical layout make this book perfect preparation for OSCE examinations.

Peripheral neuropathies represent a challenging subject for most physicians. This is an up-to-date, comprehensive, and readable book on peripheral neuropathies that includes concise information on the clinical, electrophysiological, pathological, pathogenic, and treatment aspects of the most important disorders. New molecular and serologic diagnostic tests are discussed. Sections are devoted to nerve and skin biopsy techniques and findings, quantitative sensory and autonomic reflex tests. Case examples are used liberally throughout the text. The editors: Mendell, Kissel, and Cornblath are experienced clinicians that bring complementary knowledge to each of the subjects. Additional authors have been handpicked for specific topics which add to the value of the edition.

I found this textbook to be a real bonus for my phlebotomy class. It had plenty of illustrations that complemented the text. I wound up getting an A in the class so I think the book is worth the money!" - Amazon Reviewer "Used this whole training for phlebotomy! Such a helpful informative book!" - Stacy T., Amazon Reviewer "Great book for a phlebotomy class. …lots of tips and warnings along with pertinent information and pictures." - Amazon Reviewer Enter the classroom and the laboratory with confidence! Rely on this comprehensive resource to master the techniques you need to safely obtain quality specimens. You'll understand all the hows and whys that lead to success in this rapidly changing field. Inside, you'll find the up-to-date coverage of routine procedures and their complications as well specialized procedures, quality and infection control, state-of-the-art equipment, medical terminology, ethical and legal issues, body systems, and related diagnostic laboratory tests. Videos and animations online help you to excel.

Clinical assessment is at the heart of medicine. Health professionals working in busy clinical settings, such as general practitioners, nurse practitioners and hospital doctors on-call, often have to assess patients under considerable time constraints. This book teaches the reader how to gather clinical information effectively, accurately and safely even when time is at a premium. * Provides a systematic method of collecting and assessing relevant clinical information by suggesting step-by-step examination routines, including important patient-centred questions * Focuses on common symptoms and presentations * Treatment reflects the latest in evidence based practice (including latest NICE Guidelines) * Specifically covers the clinical skills assessment (CSA) part of the Membership of the Royal College of General Practitioners (RCGP) examination * Written by an experienced medical educator and practicing GP, in consultation with a multidisciplinary team of medical students, GPs, PG trainees, hospital doctors and nurses

This atlas is an invaluable aid for pathologists and trainees who have worked with conventional smear cytology but need to familiarize themselves with the appearance seen in liquid-based cytology, which has largely replaced conventional smears for cervical screening. It includes state of the art information on normal Pap smears, normal glandular constituents, smear patterns, and inflammation, reactive changes, and repair; it also covers pathological changes, such as typical and atypical squamous cell abnormalities, high-grade intraepithelial lesions, and glandular cell abnormalities. It will be a useful guide for practitioners who need a quick reference on cytological specimens.

Cutting-edge information on databases for research and clinical practice in neuropathy! Quantitative Electroencephalographic Analysis (QEEG) Databases for Neurotherapy: Description, Validation, and Application examines the strengths and limitations of QEEG databases as a tool for the diagnosis of neurological and psychiatric disorders. This book is written by experts who have had considerable experience in either the development of databases or in working with them. This text can improve your ability to fine-tune existing protocols and develop new ones leading to better treatment, better long-term outcome, and fewer training sessions. Quantitative Electroencephalographic Analysis (QEEG) Databases for Neurotherapy can help you differentiate cognitive states, clinical disorders, and EEG changes throughout the lifespan of a patient. This book also reveals the latest technological developments and methodological practices, and comparisons are made between EEG databases to help you determine what is best for your needs. Several controversies involving quantitative EEGs are discussed, including ethical concerns and early criticisms against the use of these methods for diagnostic purposes. This book addresses important topics such as: the development of methodology for estimating the deviance from the database norms to determine abnormal brain functioning the most widely used QEEG databasestheir construction and application as well as a comparison and contrast of their features the creation of a universal set of standards for determining which database is suitable for a researcher's or practitioner's needs the use of quantitative EEG and normative databases for clinical purposesethical concerns, advantages and limitations, and the proposal for a new clinical approach for neurotherapy the comparison of QEEG reference databases in analysis and in the evaluation of Adult Attention Deficit Hyperactivity Disorder Quantitative Electroencephalographic Analysis (QEEG) Databases for Neurotherapy is supplemented with case studies, tables, figures, and graphs to support the experts' most recent findings. Furthermore, several chapters contain topographic maps to show the effects of these databases in clinical practice. This volume will be helpful to both novice and advanced neurotherapists in professions such as medicine, psychiatry, psychology, social work, nursing, and biofeedback.

" Clinical interviewing with adults is both an art and a science. This handbook will appeal to a wide range of clinical researchers, therapists, interns, and graduate students new to the complexities of the clinical interview and diagnostic process. The comprehensive range of topics and coverage that includes case illustrations with dialogue and differential diagnosis and co morbidity will be highly attractive features to researchers, professional therapists, and graduate students. The Hersen and Thomas team is highly qualified to succeed in this ambitious set of three projects. " Carolyn Brodbeck, "Chapman University"The Handbook of Clinical Interviewing with Adults is one of three interrelated handbooks on the topic of interviewing for specific populations. It presents a combination of theory and practice plus concern with diagnostic entities for readers who work, or one day will work, with adults in clinical settings.The volume begins with general issues (structured versus unstructured interview strategies, mental status examinations, selection of treatment targets and referrals, writing up the intake interview, etc.), moves to a section on major disorders most relevant to adult clients (depression, bipolar disorder, agoraphobia, posttraumatic stress disorder, eating disorders, alcohol and drug abuse, sexual dysfunction, etc.), and concludes with a chapter on special populations and issues (neurologically impaired patients, older adults, behavioral health consultation, etc.)."

In the five years since the publication of the first edition, there have been significant changes in clinical HIV care. The growth of aids in the developing world is continuing at an alarming rate, the introduction of highly-active antiretroviral therapy has presented new complications, and the increased longevity of HIV-infected patients has changed the issues involved in long-term HIV care. The second edition has been completely revised with new clinical information, drug interactions, antiretroviral therapy, and more. The succinct explanations combined with the copious illustrations make this the essential tool for the care and management of HIV patients.

This acclaimed text has comprehensive coverage of pathologies affecting the toes and finger nails. This latest edition contains new material on podiatry and investigation techniques including histopathology, ultrasonography and MRI, and dermatoscopy making this an invaluable diagnosis aid for dermatologists and podiatrists.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Concise, evidence-based coverage of the diseases and syndromes most commonly seen in clinical practice CURRENT Diagnosis and Treatment in Family Medicine, Fifth Edition is an easy-to-use guide to the diagnosis, treatment, and management of the full range of clinical conditions seen in primary care. The book covers all age groups--from pediatric to geriatric--and includes end-of-life issues. An essential clinical reference for house staff and practicing family physicians, the book is also great for USMLE Step 3 review, board certification, and maintenance of certification. *NEW content includes coverage of genetics and precision medicine use in family medicine, telehealth in family medicine, CTE and sports injuries, Zika, the opioid epidemic, Hepatitis C, expansion of the HIV section, veteran's health and PTSD, and more*Organized according to the developmental lifespan, beginning with childhood and adolescence and progressing through adulthood and senior years*Evidence-based recommendations*Conservative and pharmacologic therapies*Complementary and alternative therapies when relevant*Attention to the mental and behavioral health of patients as solitary as well as comorbid conditions*Patient education information*End-of-life issues

Information is vital for healthcare professionals striving to keep their practice current and based on the best available evidence. The Internet is playing an increasingly crucial role in life long learning of health professionals and is becoming the most practical way to access publications on clinical guidelines systematic reviews and for updating users about the key aspects of health policy. This book covers the diversity and variable value of material available on the Internet and takes a fresh approach to coping with information overload. It illustrates how simple techniques such as making and using smart maps concept maps and mind maps can help clinicians keep up-to-date and how these methods can be applied to particular areas of healthcare. It provides numerous case studies in key areas including mental health child health primary care and care of the elderly. Mapping Health on the Internet is essential reading for all healthcare professionals and will assist in their learning and continuing professional development.

The analysis of blood, bone marrow and tissue fluid specimens requires a multi-faceted approach with the integration of scientific data from a number of disciplines. No single discipline can operate in isolation or errors will occur. Flow cytometry is in a privileged position in that it can provide rapid analysis of specimens and it is often the first definitive investigation to produce results and help formulate a working diagnosis. This companion text to Practical Flow Cytometry in Haematology Diagnosis contains 100 worked examples drawn from real clinical cases presenting to the authors institution. Cases are illustrated with peripheral blood and bone marrow cytology, tissue pathology and cytogenetic and molecular data, which are integrated to generate, where appropriate, a diagnosis based on the WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. The spectrum of clinical cases includes adult and paediatric patients, and both neoplastic and reactive disorders. The cases appear in no particular order to challenge the reader to make their own diagnosis. The reader will review May Grunwald Giemsa (MGG)-stained films of peripheral blood and bone marrow aspirates presented alongside flow cytometric data and haematoxylin and eosin (H&E)-stained bone marrow and other tissue biopsy sections. Immunohistochemistry is used to further clarify the tissue lineage and cell differentiation. Cytogenetic studies using metaphase preparations are used to identify translocations and chromosome gains and losses whilst interphase fluorescence in situ hybridisation (FISH) studies and polymerase chain reaction (PCR) are used to identify gene fusions, gene rearrangements and deletions. Each case concludes with a discussion of the features that are important to making a diagnosis. The cases are also listed according to disease classification in the appendix so that the text can also be used as a reference. Practical Flow Cytometry in Haematology: 100 Worked Examples: * Provides a practical, example-based resource for flow cytometry * Demonstrates how flow cytometry results should be interpreted and applied to optimize patient care * Includes both malignant and benign conditions * Can be used in conjunction with Practical Flow Cytometry in Haematology Diagnosis, by the same author team (ISBN 9780470671207) Practical Flow Cytometry in Haematology: 100 Worked Examples is ideal for practicing haematologists and histopathologists with an interest in haematopathology, but particularly directed at trainee haematologists and scientists preparing for FRCPath and related examinations.

The only text to focus specifically on advanced health assessment/management of women This authoritative text for busy clinicians, advanced practice students, and faculty delivers essential content focused on improving the quality of healthcare provided to women/persons with a vagina across the lifespan. Brimming with new and updated content, the fifth edition reflects the most current evidence-based clinical practice guidelines available. It includes 14 new chapters written by experts in their field and the addition of disease management content, especially medications. Chapters are enhanced with management/pharmacology summary charts and case studies with discussion questions. The use of two colors improves readability, and amplified Instructor Resources include key statistics/epidemiology, learning objectives, suggested student activities and self-assessment questions, and UAB videos. Using a clear, concise outline format, this user-friendly text delivers quick, comprehensive information regarding the health assessment and management of women/persons with a vagina. It defines the role, skills, and scope of practice of different health providers and illuminates a variety of assessment skills, techniques, and procedures used by advanced practice clinicians in everyday practice. Sample assessment forms are integrated throughout along with numerous educational handouts for patients. Discussion of techniques includes a comprehensive list of requisite equipment and information on patient prep and recommended follow-up. Boxes, tables, and figures throughout reinforce key information. Purchase includes access to eBook for use on most mobile devices or computers. New to the Fifth Edition: Fourteen new chapters Telehealth in women's health Vaginal health and vaginal microscopy Mental health screening Preconception care Complementary and alternative medical therapies Adolescent health Lactation assessment and management Female veterans Male sexual and reproductive health Amenorrhea PMS/PMDD Sexual health and related problems Human trafficking The contraceptive consult Expanded breast health including breastfeeding Transgender care Updates on screening instruments Best-practice apps Case studies Management/treatment summaries Enhanced instructor package including key statistics/epidemiology, learning objectives, student activities, and self-assessment questions Two-color printing to improve readability Step-by-step videos of five office gynecology simulations from UAB Key Features: Delivered in outline, bulleted format for speedy reference Reflects the most current evidence-based clinical practice guidelines Offers easy-to-follow, step-by-step coverage of procedures Addresses treatment/management of multiple conditions Includes detailed illustrations

The "VIP" is a user-friendly, point-in-time assessment tool which provides an 'at a glance' vocal profile for the clinician, voice coach and client. It examines the potential impact of a number of specific factors on the voice: general health; vocal history; vocal health; voice care; vocal status; voice genogram; anxiety and stress; social functioning; vocal demand; and environmental factors, and offers an overview of the theory to support this choice. The questions have been carefully designed to elicit easily-recorded information from the client about a range of factors that are known to affect vocal quality. The tick-box answers then translate into the Vocal Impact Profile, a visual presentation of the areas of greatest impact on voice. In addition to offering a point-in-time profile, the "VIP" may also be used as a template for achieving change in a specific area of vulnerability and provide a robust visual reinforcement of that change over time. It is, therefore, helpful as a therapy-monitoring tool and as an evaluation of client awareness, behavioural change and clinical effectiveness. Self-administered by the client, the questionnaire should take approximately ten to fifteen minutes to complete. The clinician or voice coach enters the responses into the computer programme (supplied on downloadable resources) or transfers them manually on to the hard copy thus offering a clear visual representation of the results. Worked examples of the VIP are included, presenting six clients with very different aetiologies and with a range of vocal problems. These examples clearly demonstrate the value of the Profile and its visual impact. As a clinical tool the "VIP" provides a subjective qualitative measure, which may be used as an adjunct to other assessment procedures. In addition, it provides a concrete method of determining and ordering the factors to be targeted in terms of therapy or voice work. Using the "VIP" should shorten the time necessary for completion of case history in the case of a voice therapy client, and, when used by a voice coach, the profile will identify areas for further discussion. The Profile is not time-sensitive so it may be repeated to evaluate client awareness of vocal change and implementation of agreed strategies. The "VIP" provides the clinician or voice coach with an efficient and effective means of auditing the therapy or coaching process and promotes a holistic partnership model of intervention.

Five Stars. "Best book available if you want to learn about molecular techniques applied to clinical pathology." - Ruben A., Amazon Reviewer Five Stars. "Easy read. helped me to pass ASCP molecular bio certification exam." - Amazon Reviewer The only book you need to become certified. "Excellent book, full of details and clinical information. In addition, it describes very complexed concepts in a very easy way to understand including comprehensive diagrams." - Ruben G., Amazon Reviewer MB(ASCP) must read. "This is a must read for those laboratory professionals trying to advance their knowledge in molecular diagnostics especially for those people taking the MB(ASCP) exam. Sure it helped me pass the exam." - JR, Amazon Reviewer Meet the challenges of this rapidly expanding field: Molecular diagnostics continues to grow in importance in the clinical laboratory. This respected text will prepare your students with a grounding in the fundamental principles of molecular biology. current methods, and their clinical applications. With a focus on the application of molecular concepts to diagnostic purposes, the text explains and illustrate the use and interpretation of molecular-based assays in patient care. Now with an expanded discussion of nucleic acid sequencing, with added emphasis on next generation sequencing (NGS), and updated coverage of proteomics and mass spectrometry applications, your students will have the most current information available today.

This is the premiere clinical textbook on neonatal ultrasound diagnosis. Profusely illustrated, including Doppler sonographs in color, it contains eleven original new chapters by prominent clinician-teachers from America s foremost medical schools and teaching hospitals. The entire text focuses on definitive, clinically relevant, how-to information on normal neonatal head ultrasound, congenital malformations of the brain, sonography in periventricular leukomalacia and intraventricular hemorrhage, ultrasound of the neonatal gastrointestinal tract, sonographic evaluation of the neonatal biliary system, the neonatal adrenal gland, kidney abnormalities including embryogenesis and imaging appearance, neonatal hydronephrosis, sonography of the neonatal ovary, developmental displacement of the neonatal hip, and sonography of the neonatal spinal canal.

This new reissue of Hands On, first published in 1994, will be welcomed by all complementary and alternative medical students and practitioners. This book presents a concise approach to clinical examination in a practical and straightforward manner, and includes step-by-step illustrations of a variety of examination techniques together with checklists designed to help students and practitioners elicit clinical information from their patients quickly and efficiently.