Assessing Psychosis: A Clinician's Guide offers both a practical guide and rich clinical resource for a broad audience of mental-health practitioners seeking to sharpen their understanding of diagnostic issues, clinical concepts, and assessment methods that aid in detecting the presence of psychotic phenomena. Practicing psychiatrists, psychologists, social workers, and psychiatric nurses will find this a valuable resource for clinical practice, training, and teaching purposes.

History taking and examination skills are vitally important in everyday practice. They are examined at all levels of the undergraduate curriculum and are constantly monitored at a postgraduate level. To become proficient in history taking, key questions should be asked to quickly understand the exact nature of the illness. This invaluable guide specifies the questions required for a focused history and details the key components of the ideal examination, resulting in the development of clinical skills that are timely, comprehensive, relevant and succinct. Clearly laid out and easy-to-read, The Practical Pocket Guide to History Taking and Clinical Examination is highly recommended for medical students and junior doctors wanting a practical, quick reference to aid confidence and develop excellent clinical consultation skills. It is also ideal as an aide-memoire for exam preparation.

Pocket Guide to Gene Level Diagnostics in Clinical Practice is an abbreviated, pocket-size, quick-reference guide that provides a point-by-point synopsis of the vast wealth of information contained in CRC Handbook of Gene Level Diagnostics in Clinical Practice. All sections and subsections in the Pocket Guide are cross-referenced to corresponding pages in the Handbook. The book works well on its own as a quick reference, but also can be used in conjunction with the larger Handbook for detailed coverage and references to specific information. Pocket Guide to Gene Level Diagnostics in Clinical Practice also includes extensive supplements featuring material not included in the Handbook. These are intended to provide an up-dated, practical source of information useful to anyone involved in molecular diagnostic research and/or service. Supplements are cross-referenced to the main text of the Pocket Guide, that complement and enhance the material covered. Pocket Guide to Gene Level Diagnostics in Clinical Practice will be a handy reference for professionals and students in pathology, biotechnology, biology, and medicine.

As healthcare costs rise, so too do the costs of assessment instruments, critical tools for mental health professionals. While some traditional assessment instruments have become prohibitively expensive, as with many other fields, the Internet offers a host of more affordable and equitable alternative assessment tools at little or no cost. The pitfall of this alternative, thus far, has been the lack of vetting and quality assessment. Assessing Common Mental Health and Addiction Issues With Free-Access Instruments fills this gap by providing the first analysis and assessment of these tools, provided by some of the leading names in mental health assessment instruments. This resource identifies the most efficient free access instruments and provides summary information about administration, scoring, interpretation, psychometric integrity, and strengths and weaknesses. The book is organized around the most common broad range issues encountered by helping professionals, and whenever possible, a link to the instrument itself is provided. This is an essential text for all mental health professionals looking to expand the scope and range of their assessment instruments.

Written by a team of medical experts, this market-leading dictionary offers clear and authoritative definitions for all aspects of medical science. It features up-to-date coverage of public health medicine, medical research and general practice, drugs and pharmacology, endocrinology, cardiology and radiology, among other specialist areas. This new edition has been revised and updated to reflect advancements in medical research and practice, while over 250 new entries have been added, including American Medical Association, burden of treatment, gaming disorder, MERS, person-centred care, and Zika virus. Recommended web links and detailed illustrations complement the text, and extensive appendices offer useful lists and tables on areas such as inherited medical conditions, units of alcohol, and abbreviations and symbols. Selling over a million copies in previous editions, this is an essential A-Z for students and those working in the medical and allied professions, including nurses, pharmacists, physiotherapists, social workers, hospital administrators, and medical secretaries. It is also an invaluable home reference guide for the general reader.

Whether you are following a problem-based, an integrated or a more traditional medical course, clinical biochemistry is often viewed as one of the more challenging subjects to grasp. What you need is a single resource that not only explains the biochemical underpinnings of metabolic medicine, but also integrates laboratory findings with clinical practice. You will find all this, and more, in the eighth edition of Clinical Biochemistry and Metabolic Medicine. This well-respected text provides comprehensive and measured guidance to this complex area, reflecting the ongoing changes in our understanding of clinical biochemistry while preserving the acknowledged strenghths of previous editions: readability, a firm basis in the underlying science and a clear focus on clinical applicability.

Sensor technologies and applications are evolving rapidly driven by the demand for new sensors for monitoring and diagnostic purposes to enable improvements in human health and safety. Simultaneously, sensors are required to consume less power, be autonomous, cost less, and be connected by the Internet of Things. New sensor technologies are being developed to fulfill these needs. This book reviews the latest developments in sensor technology and gives the reader an overview of the state-of-the-art in key areas, such as sensors for diagnostics and monitoring. Features Provides an overview of sensor technologies for monitoring and diagnostics applications. Presents state-of-the-art developments in selected topics for sensors that can be used for monitoring and diagnostics in future healthcare, structural monitoring, and smart environment applications. Features contributions from leading international experts in both industry and academia. Explores application areas that include medical diagnostics and screening, health monitoring, smart textiles, and structural monitoring.

Primary care diagnostics involves interpreting and applying information obtained directly from the patient. It re-emphasises the importance of the patient's input into the diagnostic process and of using investigations only after careful consideration has been given to the costs and benefits from both the patient's and the health service's perspectives. The first edition of this book, Patient-Centred Diagnosis, was acclaimed for returning the patient to the centre of diagnostic input and focusing on the interaction between doctor and patient. This revised and augmented new edition, Primary Care Diagnostics, expands on that success; it reflects the broader and equally important issues considered by clinicians or commissioners focusing on the diagnostic approach within primary care, and includes entirely new chapters on cancer and commissioning. Family doctors and other healthcare professionals in the primary care team will find this an enlightening guide. Private and commercial providers of primary care clinical assessment and diagnostic services will also find it of great interest, as will healthcare managers, as well as policy makers and shapers. From reviews of the First Edition: 'Even the more technical sections are expressed in a straightforward language. The style is clear, flowing and engaging. Useful.' THE BRITISH JOURNAL OF GENERAL PRACTICE 'Thought provoking. Clear, understandable and uses real examples from general practice. This is a book for GPs who wish to take a step back from daily practice and think about the reasons behind their actions.' PULSE

'...approaches the consultation intuitively ... The book oozes with patience for the patient and for the reader. What better prescription for the clinic could the practitioner need?' Glycosmedia (of the Fifth Edition) '... this is a book worth having available at the point of care for health professionals, including doctors, nurses, undergraduates and postgraduates, to help them make sense of common symptoms. With the help of the authors' opinions in combination with our own experience we should then be able to make better clinical decisions.' Sultan Qaboos University Medical Journal (of the Fourth Edition) Across its six editions, Symptom Sorter has excelled in redressing the balance between symptoms and diagnoses to become the essential handbook to accompany the consultation in primary care. Presenting a multitude of symptoms commonly encountered in primary care, these are meticulously explored using the red flags, top tips and ready reckoner format for sorting symptoms that have made previous editions so popular and respected. This revised and updated sixth edition includes several new chapters and features expanded coverage of paediatric symptoms. Key features: * Fully updated, with 'investigations' sections amended in line with latest guidelines and significant revisions throughout * Brand new chapters on acute abdominal pain in childhood, hand and wrist swellings, diarrhoea in children, loin pain, rectal bleeding in children, vomiting in babies, skinfold rash and dysuria * Consistent and logical presentation enables speedy access * Replicates accurately the experience in the consultation or clinic An invaluable reference for all general practitioners, especially GP trainers and registrars, this new edition of Symptom Sorter is also highly recommended for advanced nurse practitioners, A&E nurses and pharmacists requiring a concise, easy-to-use guide. The authors: Keith Hopcroft is a GP in Basildon, Essex, UK, an associate trainer, an editorial adviser to Pulse, and a medical writer and columnist. Vincent Forte is a former GP based in Norfolk, UK

Written specifically for urological trainees by a distinguished team of contributors, this third edition of The Scientific Basis of Urology provides the reader with a thorough coverage of urology. Every area, function, illness and treatment of the urinary tract, along with specific discussions of the relevant anatomy and physiology, is included in clearly written text, abundantly illustrated with full color photographs and diagrams. Each chapter takes the basic principles of its topic area and expands upon them to ensure maximum understanding.

Entirely new chapters in the Third Edition:

• Genetic and Biological Alterations in Cancer
• The Scientific Basis of Male Hypogonadism
• Minimally Invasive Technologies in the Treatment of Renal and Prostate Cancer
• Preoperative Assessment

Non-Invasive Instrumentation and Measurement in Medical Diagnosis, Second Edition discusses NIMD as a rapidly growing, interdisciplinary field. The contents within this second edition text is derived from Professor Robert B. Northrop's experience teaching for over 35 years in the Biomedical Engineering Department at the University of Connecticut. The text focusses on the instruments and procedures which are used for non-invasive medical diagnosis and therapy, highlighting why NIMD is the preferred procedure, whenever possible, to avoid the risks and expenses associated with surgically opening the body surface. This second edition also covers a wide spectrum of NIMD topics including: x-ray bone densitometry by the DEXA method; tissue fluorescence spectroscopy; optical interferometric measurement of nanometer tissue displacements; laser Doppler velocimetry; pulse oximetry; and applications of Raman spectroscopy in detecting cancer, to name a few. This book is intended for use in an introductory classroom course on Non-Invasive Medical Instrumentation and Measurements taken by juniors, seniors, and graduate students in Biomedical Engineering. It will also serve as a reference book for medical students and other health professionals intrigued by the topic. Practicing physicians, nurses, physicists, and biophysicists interested in learning state of the art techniques in this critical field will also find this text valuable. Non-Invasive Instrumentation and Measurement in Medical Diagnosis, Second Edition concludes with an expansive index, bibliography, as well as a comprehensive glossary for future reference and reading.

This book is a compilation of endoscopic images of the upper gastrointestinal tract. The 3rd edition is enriched with high-resolution digital images highlighting the classification and staging of endoscopically relevant diseases. Serial documentation of diseases and procedures like corrosive injury, variceal obliteration, peptic ulcer etc. provides a complete, informative and interesting perspective. Rare conditions like Dieulafoy's disease and Gastric antral vascular ectasia (GAVE) have been extensively discussed along with common diseases of the GI tract. This book outlines the technique and interpretation of endoscopic images proving to be a helpful guide to endoscopy practitioners. Key Features Explores various GI tract diseases through coloured, high resolution clinical photographs. Serves as a useful reckoner for trainee endoscopists and practitioners pursuing gastroenterology or gastrointestinal endoscopy. The text is updated with tables, flowcharts, classifications and international treatment guidelines.

There is a new trend in anti-cancer therapeutics development: a targeted therapy and precision medicine that targets a subgroup of patients with specific biomarkers. An in vitro diagnostic (IVD) assay is required to identify a subgroup of cancer patients who would benefit from the targeted therapy, or not likely benefit, or have a high risk of side effects from the specific drug treatment. This IVD or medical device is called a companion diagnostic (CDx) assay. It is key to have a robust CDx assay or device for the success of targeted therapy and precision medicine. This book covers the technical, historical, clinical, and regulatory aspects of CDx in precision medicine. Clearly, more and more newly developed oncology drugs will require accompanying CDx assays, and this book, with chapters contributed by renowned oncologists, provides a comprehensive foundation for the knowledge and application of CDx for precision medicine.

For many centuries, mankind has tried to learn about his health. Initially, during the pre-technological period, he could only rely on his senses. Then there were simple tools to help the senses. The breakthrough turned out to be the discovery of X-rays, which gave insight into the human body. Contemporary medical diagnostics are increasingly supported by information technology, which for example offers a very thorough analysis of the tissue image or the pathology differentiation. It also offers possibilities for very early preventive diagnosis. Under the influence of information technology, 'traditional' diagnostic techniques and new ones are changing. More and more often the same methods can be used for both medical and technical diagnostics. In addition, methodologies are developed that are inspired by the functioning of living organisms. Information Technology in Medical Diagnostics II is the second volume in a series showing the latest advances in information technologies directly or indirectly applied to medical diagnostics. Unlike the previous book, this volume does not contain closed chapters, but rather extended versions of presentations made during two conferences: XLVIII International Scientific and Practical Conference 'Application of Lasers in Medicine and Biology' (Kharkov, Ukraine) and the International Scientific Internet conference 'Computer graphics and image processing' (Vinnitsa, Ukriane), both held in May 2018. Information Technology in Medical Diagnostics II links technological issues to medical and biological issues, and will be valuable to academics and professionals interested in medical diagnostics and IT.

Objective Structured Clinical Examinations (OSCEs) are commonly encountered at all levels of medical school including the final MBBS examination. OSCEs also play an important role at postgraduate level and are used to assess competency in the Foundation Years. One of the fundamental requirements of passing the OSCE is an understanding of the standard which is expected and an appreciation of how to demonstrate this. This book discusses 170 commonly encountered OSCE scenarios, with a step-by-step approach to maximise your chances of success in the examination. The scenarios are presented with sufficient background information to enable candidates to tackle variations. This comprehensive book, covering both surgery and medicine, overcomes any problems of a tick-box approach and insufficient detail faced by some alternative texts. The clear, straight-forward style and logical layout make this book perfect preparation for OSCE examinations.

There are many problems in working psychotherapeutically across cultures, with numerous examples of failure to understand cultural issues. For example, the ignorance of traditional family structures can lead to major diagnostic and therapeutic errors. These errors include potentially disastrous transference relationship interpretations, the confounding of traditional beliefs with psychiatric symptoms, and a lack of awareness of differences in presenting symptomology. This book explains the theories and techniques of intercultural therapy.

The second edition retains many of the ideas and practices developed in the first edition, but has been updated throughout to include the latest literature, and includes a new introductory chapter. A range of different views on intercultural therapy are given by a group of specialists who have pioneered this developing area.

The late Jafar Kareem BSc was a member of the British Association of Psychotherapists, a member of the London Centre for Psychotherapy, and Founder and Clinical Director of Nafsiyat Intercultural Therapy Centre.

Roland Littlewood BSc, MB, DPhil, FRCPsych, is Professor of Psychiatry and Anthropology, University College London, Joint Director of the UCL Centre for Medical Anthropology, Consultant Psychiatrist, Middlesex Hospital, and Medical Advisor, Nafsiyat.

The ability to record an accurate and complete patient history, and to examine the patient appropriately in response to the history described, are fundamental skills that all student doctors need to acquire at an early stage in training. 'Making Sense of Clinical Examination of the Adult Patient' provides invaluable 'hands-on' guidance for medical students and junior doctors when presented with a new patient. Written from a very practical standpoint, Dr Douglas Model shares his extensive experience of teaching this subject. Real life scenarios are interspersed throughout the text. On reading 'Making Sense of Clinical Examination of the Adult Patient', the reader is given: practical advice on recording all aspects of a patient's history, including the present complaint, past medical history, and family history; and detailed guidance on performing an examination of each body system.

This invaluable guide for nurses improves the skills and knowledge required to consult effectively with patients. It is highly practical, easy to read and comprehend, and is designed for use in daily practice, and as an aid for professional development. The 'Consultation Assessment and Improvement Instrument for Nurses' (CAIIN) concept is introduced, and sample forms, suggested strategies and tables containing key information are also provided. The recent substantial changes that have taken place in health service structures, staffing arrangements and nursing practice have led to more nurses working in first contact roles and within nurse-led services. Nurses at all levels in primary and secondary care, including those in pre-registration training will find this guide vital, as will nurses considering taking on autonomous roles such as independent prescribing. It is also highly suitable for nurse lecturers, nurse managers, learning and health service managers, and undergraduate and postgraduate nursing students.

Evidence based medicine is defined as the conscientious explicit and judicious use of current best evidence in making decisions about the care of individual patients. This superb collection takes a critical view of this concept and examines the economic implications of its imposition.

This volume is intended to help practicing therapists and counselors, as well as students of these professions, to explore more fully and systematically the processes of self-improvement in their work and lives. It captures the reader's interest by discussing some of the therapist's personal and professional challenges in a refreshingly honest way. The book deals with a number of standard areas of self-supervision, such as self-monitoring and working with mentors, and provides a framework and a process for examining one's own strengths and weaknesses, then taking steps to improve excellence across a host of domains.

Epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) is a clinically important driver alteration affecting approximately one-third of lung cancer patients. Treatments for EGFR-exon 19 deletion and exon 21 L858R NSCLC have evolved over the last decade from first-generation reversible tyrosine kinase inhibitors (TKI) to third-generation irreversible TKIs, of which osimertinib has been the widely accepted as first-line therapy. Despite survival improvement seen with osimertinib and its efficacy against acquired T790M mutation, resistance through on-target and off-target pathways eventually develop. This Element describes the structural biology and pathophysiology of EGFR-mutant NSCLC and discusses past, current, and future treatment options in the metastatic, neoadjuvant, and adjuvant settings. It describes the biology and recently approved treatment for EGFR-exon 20 insertion mutation and the treatment for the uncommon exon 18 (G719X), 20 (S768I), and 21 (L861Q) mutations. It also outlines the promising clinical applications of circulating tumor DNA (ctDNA).

For many centuries, people have tried to learn about the state of their health. Initially, in the pre-technological period, they had to rely only on their senses. Then there were simple tools to help the human senses. The discovery of X-rays, which allowed people to look "inside" the body, turned out to be a major breakthrough. Contemporary medical diagnostics is increasingly being assisted by information technology that allows, for example, thorough image tissue analysis or pathology differentiation. They also allow very early preventive diagnostics. Influenced by information technology, "classic" diagnostic techniques change and new ones arise. Information Technology in Medical Diagnostics presents selected and extended conference papers from Polish, Ukrainian and Kazakh scientists. They address problems of the application of new methods of image processing for analysis of medical images, new methods of classification of medical data as well as new medical imaging methods. Some of the presented technologies are inspired by the functioning of living organisms. Information Technology in Medical Diagnostics is of interest not only to academics and engineers, but also to professionals involved in biomedical engineering, and seeking for solutions for issues that cannot be solved with the help of "traditional" technologies.

Examining children presents unique challenges for trainees and new doctors in paediatrics. Paediatric patients vary greatly in age and development, often find it difficult to describe their symptoms, and can behave unpredictably in clinical settings. Clinical Examination Skills in Paediatrics helps MRCPCH candidates and other practitioners learn effective history taking and fundamental examination techniques. Clear and concise chapters-with contributions from a team of paediatric specialists-demonstrate the clinical examination and questioning techniques used in daily practice. Emphasis on the intellectual processes involved in decision making assists both trainees preparing for a formal examination as well as new clinicians faced with a difficult diagnostic problem. Topics include cardiovascular and respiratory examination, examining a child with a neuromuscular disorder, musculoskeletal examination, and taking history from a child with diabetes and a rheumatological condition. Includes access to a companion website containing high-quality videos that demonstrate techniques, procedures and approaches Features commentary by experienced practitioners which offer observations and deductions at each stage of the examination process Offers tips for communicating effectively with the patients using appropriate lay terms Helps translate the symptoms and signs experienced by patients into medical-speak Covers all the skills tested in the MRCPCH Clinical exam Clinical Examination Skills in Paediatrics is the perfect study and reference guide for paediatrics trainees, MRCPCH candidates, foundation doctors, allied healthcare professionals, and anyone looking to improve their clinical and communication skills in paediatrics.

This straightforward guide to taking patient history comprehensively covers all of the commonly seen OSCE scenarios within the current undergraduate medical curriculum. The Easy Guide to Focused History Taking for OSCEs includes introductory chapters with general OSCE guidance, mapping onto the Calgary-Cambridge model. These include tips from recently qualified doctors and highly respected physicians and surgeons who commonly examine OSCEs, as well as a sample OSCE marking scheme. The book then covers 56 histories based on presenting complaints - more than any other text on the market - thoroughly testing both knowledge and examination technique. Each history is based around the exam requirements, with mnemonics, 'red flag' symptom boxes and list-based breakdowns to aid prompt recall. Common and serious differentials are highlighted, as well as investigations to help rule out the serious conditions. Each section concludes by outlining key aspects for each differential diagnosis as well as a list of investigations and management options. With this book, every student will be well equipped to tackle any clinical problem, in the OSCE examination and also in their continued professional practice.

With the development of rapidly increasing medical imaging modalities and their applications, the need for computers and computing in image generation, processing, visualization, archival, transmission, modeling, and analysis has grown substantially. Computers are being integrated into almost every medical imaging system. Medical Image Analysis and Informatics demonstrates how quantitative analysis becomes possible by the application of computational procedures to medical images. Furthermore, it shows how quantitative and objective analysis facilitated by medical image informatics, CBIR, and CAD could lead to improved diagnosis by physicians. Whereas CAD has become a part of the clinical workflow in the detection of breast cancer with mammograms, it is not yet established in other applications. CBIR is an alternative and complementary approach for image retrieval based on measures derived from images, which could also facilitate CAD. This book shows how digital image processing techniques can assist in quantitative analysis of medical images, how pattern recognition and classification techniques can facilitate CAD, and how CAD systems can assist in achieving efficient diagnosis, in designing optimal treatment protocols, in analyzing the effects of or response to treatment, and in clinical management of various conditions. The book affirms that medical imaging, medical image analysis, medical image informatics, CBIR, and CAD are proven as well as essential techniques for health care.