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Dehydrogenases - Requiring Nicotinamide Coenzymes (Paperback, Softcover reprint of the original 1st ed. 1980)
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Dehydrogenases - Requiring Nicotinamide Coenzymes (Paperback, Softcover reprint of the original 1st ed. 1980)
Series: Experientia Supplementum, 36
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This book brings together lmportant work on the structure and
function of the dehydrogenases requiring nicotinamide coenzymes.
The structure and function of lactate dehydrogen- ase, alcohol
dehydrogenase, and glyceraldehyde 3-phosphate dehydrogenase are
compared. These are the relatively simple oligomeric dehydrogenases
for which very extensive structural and mechanistic information is
available. Kinetic studies are dealt with in general terms, with
selected examples. Genetic and structural relationships revealed by
primary structure are discussed. General features of the
specificity of dehydrogen- ase reactions are described. The
pyridine nucleotide - disulphide oxidoreductases exemplify a type
of multicomponent enzyme complex. Lipoamide dehydrogenase,
glutathione reductase, and thioredoxin reduct- ase are described
and compared. The fatty acid synthesizing systems of some organ-
isms are nonaggregated, whereas in other organisms they are
multienzyme complexes containing, in animal tissues for example,
two closely related multifunctional polypeptide chains. The
dehydrogenase activities of the fatty acid syn- thesizing systems
afford many points of interest, which are described and discussed.
Hydroxymethylglutaryl-CoA reductase occupies a key position in the
synthesis of isoprenoid compounds, including cholesterol. It
probably occurs in all forms of life; in animal cells it is a
microsomal enzyme. Its properties are reviewed.
General
Imprint: |
Springer Basel
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Country of origin: |
Switzerland |
Series: |
Experientia Supplementum, 36 |
Release date: |
September 2014 |
First published: |
1980 |
Authors: |
Jonathan
|
Dimensions: |
244 x 170 x 15mm (L x W x T) |
Format: |
Paperback
|
Pages: |
276 |
Edition: |
Softcover reprint of the original 1st ed. 1980 |
ISBN-13: |
978-3-03-485421-4 |
Categories: |
Books >
Science & Mathematics >
Biology, life sciences >
Biochemistry >
Enzymology
|
LSN: |
3-03-485421-8 |
Barcode: |
9783034854214 |
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